KEGG ENZYME: 5.3.1.34

ENZYME: 5.3.1.34

Entry

EC 5.3.1.34                 Enzyme

Name

D-erythrulose 4-phosphate isomerase;
eryI (gene name)

Class

Isomerases;
Intramolecular oxidoreductases;
Interconverting aldoses and ketoses, and related compounds

Sysname

D-erythrulose-4-phosphate ketose-aldose isomerase

Reaction(IUBMB)

D-erythrulose-4-phosphate = D-erythrose 4-phosphate [RN:R11333]

Reaction(KEGG)

R11333

Substrate

D-erythrulose-4-phosphate

Product

D-erythrose 4-phosphate [CPD:C00279]

Comment

The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism.

History

EC 5.3.1.34 created 2016

Orthology

K21911

D-erythrulose 4-phosphate isomerase

Genes

SPIU:

SPICUR_04435

SROS:

BBH56_05220

MMW:	Mmwyl1_3112

MME:	Marme_1598

MPRI:

MP3633_1151(eryI)

MARD:

IBG28_06505

MFOI:

JSY38_15340

MPRF:

J8N69_12395

MLN:	A9174_29235

MCI:	Mesci_5318

MCIC:

A4R28_00520

MOP:	Mesop_5783

MAM:	Mesau_05277

MAMO:

A6B35_10960

MESW:

A9K65_029070

MESM:

EJ066_15450

MHUA:

MCHK_0795

MJR:	EB229_29815

MERD:

EB233_25860

MESR:

FGU64_19825

MMEI:

LRP31_30035

SME:	SMc01613(rpiB)

SMK:	Sinme_2205

SMQ:	SinmeB_2049

SMX:	SM11_chr1034(rpiB)

SMI:	BN406_02049(rpiB)

SMEG:

C770_GR4Chr2283

SMEL:

SM2011_c01613(rpiB)

SMER:

DU99_12480

SMD:

Smed_2149

RHI:	NGR_b17380(rpiB) NGR_c06620

SFH:	SFHH103_05478(rpiB)

SFD:	USDA257_c12880(ywlF)

SIX:	BSY16_3604

SAME:

SAMCFNEI73_pC1160(rpiB)

SINO:

SS05631_b56470

ESJ:	SJ05684_c12450

ENU:	PYH37_004696

SKM:	PZL22_002561

EAD:	OV14_3638(rpiB)

EAH:	FA04_11215

ECAA:

J3R84_11370

ENP:	JVX98_08470

ARUI:

G6M88_17485

ASAL:

CFBP5507_25045

ALEG:

CFBP4996_05400

RET:	RHE_PF00039(rpiB)

REC:	RHECIAT_PC0000967(rpiB)

REL:	REMIM1_PF00043

REI:	IE4771_PA00089

RLE:	pRL120210(rpiB2)

RLT:	Rleg2_4652

RLG:

Rleg_5329

RLB:	RLEG3_09660

RTR:	RTCIAT899_PC05540

RHL:	LPU83_pLPU83c0536(rpiB)

RGA:	RGR602_PA00073 RGR602_PC00572

RHN:	AMJ98_PE00042

RPHA:

AMC79_PD00974

RHX:	AMK02_PD00045

REZ:	AMJ99_PD00042

RJG:	CCGE525_32085

RHR:	CKA34_19850

RGR:	FZ934_27750

RAD:	CO657_24140 CO657_28370

RII:	FFM53_025700

RBAN:

J2J98_21260 J2J98_22040

RRG:	J3P73_25010

RLS:	HB780_03485

RAW:	NE851_33210

RSUL:

N2599_32170

RLW:	RlegWSM1455_24535

RRHO:

PR018_27275

RTU:	PR017_26050

ARA:	Arad_7453(rpiB)

RBW:	RLCC275e_24300

SHZ:

shn_16455

SZO:	K8M09_21690

SOJ:	K6301_18155

SSUM:

Q9314_21735

BME:

BMEII0424

BMEL:

DK63_2815

BMI:	BMEA_B0849

BMZ:	BM28_B0837

BMG:	BM590_B0834

BMW:	BMNI_II0810

BMEE:

DK62_2583

BMF:

BAB2_0366

BMB:	BruAb2_0362

BMC:	BAbS19_II03440

BAA:	BAA13334_II00813

BABO:

DK55_2356

BABR:

DO74_2776

BABT:

DK49_2876

BABB:

DK48_2335

BABU:

DK53_2366

BABS:

DK51_2945

BABC:

DO78_2694

BMS:

BRA0870

BSI:	BS1330_II0863

BSF:	BSS2_II0824

BSUI:

BSSP1_II0815

BSUP:

BSPT1_II0812

BSUV:

BSPT2_II0813

BSUC:

BSSP2_II0824

BMT:	BSUIS_B0863

BSZ:

DK67_2824

BSV:	BSVBI22_B0862

BSW:	IY71_15345

BSG:	IY72_15295

BOV:

BOV_A0817

BCS:	BCAN_B0888

BSK:	BCA52141_II1814

BOL:	BCOUA_II0870

BCAR:

DK60_2561

BCAS:

DA85_14635

BMR:

BMI_II864

BPP:

BPI_II926

BPV:

DK65_2779

BCET:

V910_200422

BCEE:

V568_200474

BVL:	BF3285c2_0394

BRU:	BFS01_12145

BRJ:	BKD03_02220

OIN:	IAR37_20595

BIO:	BR141012304_20146

OAN:

Oant_2905

OAH:

DR92_3600

OPS:	A8A54_12245

BPSN:

NIK97_15385

OCH:	CES85_5813

OCR:	HGK82_17620

OCL:	GTN27_20240

LNE:	FZC33_03450 FZC33_06365

MMED:

Mame_00690(ywlF)

AUA:	M673_19605

AALA:

IGS74_12650

AALM:

LUX29_14540

LABT:

FIU93_29525(ywlF)

LAGG:

B0E33_29600

LIZ:	LGH83_10305

RDE:	RD1_3624(rpiB)

RLI:	RLO149_c008410

OAR:	OA238_c42220

CMAR:

IMCC12053_1880

MALG:

MALG_04499

TPRO:

Ga0080559_TMP2167

MALU:

KU6B_05340

PALX:

GQA70_00775

PARR:

EOJ32_06635

PAAK:

FIU66_08995

PLIA:

E4191_09960

PMAU:

CP157_02315(eryI)

PSEW:

JHW44_18110

PSAP:

JHX88_17230

PFIS:

JHX87_06730

DON:	BSK21_15600

RBZ:	B9057_14890

THW:	BMG03_00145

TEC:	AKL02_018100

GFU:	KM031_19915

PAMO:

BAR1_01160

PPAF:

I8N54_11360

PBAE:

P8S53_18485

RBX:	I3V23_01190

GOX:

GOX2218

GOH:

B932_2979

GOY:	GLS_c23670(ywlF)

GAL:	A0U94_09875

GTI:	FXF46_12665

KNA:	B0W47_16015

ABG:	Asbog_01352

KBA:	A0U89_08590

NCH:	A0U93_12980

LCK:	HN018_15875 HN018_21610

KDP:	N5W20_03480

THAC:

CSC3H3_22340

CCOM:

I6K69_15065

ROB:

CK5_24940

SCW:	TU94_04840

SAMB:

SAM23877_1304

SLE:	sle_58730(sle_58730)

SPAV:

Spa2297_04435

» show all

Reference

1 [PMID:25453104]

Authors

Barbier T, Collard F, Zuniga-Ripa A, Moriyon I, Godard T, Becker J, Wittmann C, Van Schaftingen E, Letesson JJ

Title

Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella.

Journal

Proc Natl Acad Sci U S A 111:17815-20 (2014)
DOI:10.1073/pnas.1414622111

Sequence

[bmf:BAB2_0366]

Other DBs

ExplorEnz - The Enzyme Database:

5.3.1.34

IUBMB Enzyme Nomenclature:

5.3.1.34

ExPASy - ENZYME nomenclature database:

5.3.1.34

BRENDA, the Enzyme Database:

5.3.1.34

DBGET integrated database retrieval system