KEGG   ENZYME: 5.4.99.34
Entry
EC 5.4.99.34                Enzyme                                 
Name
germanicol synthase;
RsM1;
(S)-2,3-epoxysqualene mutase (cyclizing, germanicol-forming)
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualenee mutase (cyclizing, germanicol-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = germanicol [RN:R09710]
Reaction(KEGG)
R09710
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
germanicol [CPD:C19833]
Comment
The enzyme produces germanicol, beta-amyrin and lupeol in the ratio 63:33:4.
History
EC 5.4.99.34 created 2011
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15818  germanicol synthase
Genes
PVY116134158
Reference
1  [PMID:17803686]
  Authors
Basyuni M, Oku H, Tsujimoto E, Kinjo K, Baba S, Takara K
  Title
Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae.
  Journal
FEBS J 274:5028-42 (2007)
DOI:10.1111/j.1742-4658.2007.06025.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.34
IUBMB Enzyme Nomenclature: 5.4.99.34
ExPASy - ENZYME nomenclature database: 5.4.99.34
BRENDA, the Enzyme Database: 5.4.99.34

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