KEGG   ENZYME: 5.4.99.35
Entry
EC 5.4.99.35                Enzyme                                 
Name
taraxerol synthase;
RsM2;
(S)-2,3-epoxysqualene mutase (cyclizing, taraxerol-forming)
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, taraxerol-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = taraxerol [RN:R09476]
Reaction(KEGG)
R09476
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
taraxerol [CPD:C08637]
Comment
The enzyme gives taraxerol, beta-amyrin and lupeol in the ratio 70:17:13.
History
EC 5.4.99.35 created 2011
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K15819  taraxerol synthase
Reference
1  [PMID:17803686]
  Authors
Basyuni M, Oku H, Tsujimoto E, Kinjo K, Baba S, Takara K
  Title
Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae.
  Journal
FEBS J 274:5028-42 (2007)
DOI:10.1111/j.1742-4658.2007.06025.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.35
IUBMB Enzyme Nomenclature: 5.4.99.35
ExPASy - ENZYME nomenclature database: 5.4.99.35
BRENDA, the Enzyme Database: 5.4.99.35

DBGET integrated database retrieval system