KEGG   ENZYME: 5.4.99.47
Entry
EC 5.4.99.47                Enzyme                                 
Name
parkeol synthase
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, parkeol-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = parkeol [RN:R09907]
Reaction(KEGG)
R09907
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
parkeol [CPD:C19918]
Comment
The enzyme from rice (Oryza sativa) produces parkeol as a single product [1].
History
EC 5.4.99.47 created 2011
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K19010  parkeol synthase
Genes
OSA9268610
DOSAOs11t0189600-01(Os11g0189600)
OGL127754163
SBI8060013
PHAI112902702
Reference
1  [PMID:21526825]
  Authors
Ito R, Mori K, Hashimoto I, Nakano C, Sato T, Hoshino T
  Title
Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases.
  Journal
Org Lett 13:2678-81 (2011)
DOI:10.1021/ol200777d
  Sequence
[osa:9268610]
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.47
IUBMB Enzyme Nomenclature: 5.4.99.47
ExPASy - ENZYME nomenclature database: 5.4.99.47
BRENDA, the Enzyme Database: 5.4.99.47

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