Entry
Name
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
BRITE hierarchy
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, glutinol-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = glutinol [RN:
R09909 ]
Reaction(KEGG)
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:
C01054 ]
Product
Comment
The enzyme from Kalanchoe daigremontiana also gives traces of other triterpenoids.
History
EC 5.4.99.49 created 2011
Orthology
Reference
Authors
Wang Z, Yeats T, Han H, Jetter R
Title
Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 5.4.99.49