KEGG   ENZYME: 5.4.99.49
Entry
EC 5.4.99.49                Enzyme                                 
Name
glutinol synthase
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, glutinol-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = glutinol [RN:R09909]
Reaction(KEGG)
R09909
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
glutinol [CPD:C20188]
Comment
The enzyme from Kalanchoe daigremontiana also gives traces of other triterpenoids.
History
EC 5.4.99.49 created 2011
Orthology
K21941  glutinol synthase
Reference
1  [PMID:20610397]
  Authors
Wang Z, Yeats T, Han H, Jetter R
  Title
Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids.
  Journal
J Biol Chem 285:29703-12 (2010)
DOI:10.1074/jbc.M109.098871
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.49
IUBMB Enzyme Nomenclature: 5.4.99.49
ExPASy - ENZYME nomenclature database: 5.4.99.49
BRENDA, the Enzyme Database: 5.4.99.49

DBGET integrated database retrieval system