| Entry |
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| Name |
pre-alpha-onocerin synthase;
LCC
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| Class |
Isomerases;
Intramolecular transferases;
Transferring other groups
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| Sysname |
(3S,22S)-2,3:22,23-diepoxy-2,3,22,23-tetrahydrosqualene mutase (cyclizing, pre-alpha-onocerin-forming)
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| Reaction(IUBMB) |
(3S,22S)-2,3:22,23-diepoxy-2,3,22,23-tetrahydrosqualene = pre-alpha-onocerin [RN: R11867]
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| Reaction(KEGG) |
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| Substrate |
(3S,22S)-2,3:22,23-diepoxy-2,3,22,23-tetrahydrosqualene [CPD: C21732]
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| Product |
pre-alpha-onocerin [CPD: C21733]
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| Comment |
Isolated from the plant Lycopodium clavatum. The enzyme does not act on (3S)-2,3-epoxy-2,3-dihydrosqualene and does not form any alpha-onocerin.
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| History |
EC 5.4.99.65 created 2017
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| Orthology |
| K22964 | pre-alpha-onocerin synthase |
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| Reference |
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| Authors |
Araki T, Saga Y, Marugami M, Otaka J, Araya H, Saito K, Yamazaki M, Suzuki H, Kushiro T |
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| Title |
Onocerin Biosynthesis Requires Two Highly Dedicated Triterpene Cyclases in a Fern Lycopodium clavatum. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 5.4.99.65 |
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