KEGG ENZYME: 5.5.1.25

ENZYME: 5.5.1.25

Entry

EC 5.5.1.25                 Enzyme

Name

3,6-anhydro-L-galactonate cycloisomerase;
3,6-anhydro-alpha-L-galactonate lyase (ring-opening);
3,6-anhydro-alpha-L-galactonate cycloisomerase

Class

Isomerases;
Intramolecular lyases;
Intramolecular lyases (only sub-subclass identified to date)

Sysname

3,6-anhydro-L-galactonate lyase (ring-opening)

Reaction(IUBMB)

3,6-anhydro-L-galactonate = 2-dehydro-3-deoxy-L-galactonate

Reaction(KEGG)

(other) R10900

Substrate

3,6-anhydro-L-galactonate [CPD:C20903]

Product

2-dehydro-3-deoxy-L-galactonate [CPD:C20680]

Comment

The enzyme, characterized from the marine bacteria Vibrio sp. EJY3 and Postechiella marina M091, is involved in a degradation pathway for 3,6-anhydro-alpha-L-galactopyranose, a major component of the polysaccharides of red macroalgae.

History

EC 5.5.1.25 created 2014, modified 2015

Orthology

K20549

3,6-anhydro-L-galactonate cycloisomerase

Genes

VEJ:	VEJY3_09370

VAS:	GT360_06845

Reference

1 [PMID:25156229]

Authors

Yun EJ, Lee S, Kim HT, Pelton JG, Kim S, Ko HJ, Choi IG, Kim KH

Title

The novel catabolic pathway of 3,6-anhydro-L-galactose, the main component of red macroalgae, in a marine bacterium.

Journal

Environ Microbiol 17:1677-88 (2015)
DOI:10.1111/1462-2920.12607

Sequence

[vej:VEJY3_09370]

Reference

Authors

Lee, S.B., Cho, S.J., Kim, J.A., Lee, S.Y., Kim, S.M. and Lim, H.S.

Title

Metabolic pathway of 3,6-anhydro-L-galactose in agar-degrading microorganisms.

Journal

Biotechnol Bioprocess Eng 19:866-878 (2014)

Other DBs

ExplorEnz - The Enzyme Database:

5.5.1.25

IUBMB Enzyme Nomenclature:

5.5.1.25

ExPASy - ENZYME nomenclature database:

5.5.1.25

BRENDA, the Enzyme Database:

5.5.1.25

DBGET integrated database retrieval system