ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
kinesin associated with a microtubule at position n
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
kinesin associated with a microtubule at position n-1 (toward the minus end)
Comment
Kinesins are a family of motor proteins that move unidirectionally along microtubules as they hydrolyse ATP and are involved in organelle movement. This enzyme is similar to EC 5.6.1.3, plus-end-directed kinesin ATPase, but the organization of the different domains differs, resulting in movement in the opposite direction along the microtubules.
History
EC 5.6.1.4 created 2000 as 3.6.4.5, transferred 2018 to EC 5.6.1.4