Entry |
|
Name |
6-carboxyhexanoate---CoA ligase;
6-carboxyhexanoyl-CoA synthetase;
pimelyl-CoA synthetase
|
Class |
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
|
Sysname |
6-carboxyhexanoate:CoA ligase (AMP-forming)
|
Reaction(IUBMB) |
ATP + 6-carboxyhexanoate + CoA = AMP + diphosphate + 6-carboxyhexanoyl-CoA [RN: R03209]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
History |
EC 6.2.1.14 created 1983
|
Pathway |
|
Orthology |
K01906 | 6-carboxyhexanoate--CoA ligase |
|
Genes |
BAZ: | BAMTA208_07885(bioW) |
BSON: | S101395_00961(bioW) |
SAX: | USA300HOU_2407(bioW) |
SAUT: | SAI1T1_2017980(bioW) |
SAUJ: | SAI2T2_1017990(bioW) |
SAUK: | SAI3T3_1017980(bioW) |
SAUQ: | SAI4T8_1017990(bioW) |
SAUV: | SAI7S6_1017980(bioW) |
SAUW: | SAI5S5_1017920(bioW) |
SAUX: | SAI6T6_1017920(bioW) |
SAUY: | SAI8T7_1017960(bioW) |
SDP: | NCTC12225_00148(bioW) |
SSH: | NCTC13712_02374(bioW) |
PHAR: | NCTC13077_01223(bioW) |
VRM: | 44547418_01018(bioW) |
VDN: | NCTC11831_00891(bioW) |
DHO: | Dia5BBH33_18170(bioW) |
PFAC: | PFJ30894_02090(bioW) |
CDIP: | ERS451417_01397(bioW) |
CUN: | Cul210932_1345(bioW) |
CUQ: | Cul210931_1242(bioW) |
CUJ: | CUL131002_1273(bioW) |
CMIN: | NCTC10288_01030(bioW) |
CGRN: | 4412665_00276(bioW) |
» show all
|
Reference |
|
Authors |
Izumi Y, Morita H, Sato K, Tani Y, Ogata K. |
Title |
Synthesis of biotin-vitamers from pimelic acid and coenzyme A by cell-free extracts of various bacteria. |
Journal |
|
Reference |
2 |
Authors |
Izumi, Y., Morita, H., Tani, Y. and Ogata, K. |
Title |
The pimelyl-CoA synthetase responsible for the first step in biotin biosynthesis by microorganisms. |
Journal |
Agric Biol Chem 38:2257-2262 (1974) |
Other DBs |
ExplorEnz - The Enzyme Database: | 6.2.1.14 |
ExPASy - ENZYME nomenclature database: | 6.2.1.14 |
|