Entry
Name
isophthalate---CoA ligase;
IPCL
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
BRITE hierarchy
Sysname
isophthalate:CoA ligase (AMP-forming)
Reaction(IUBMB)
ATP + isophthalate + CoA = AMP + diphosphate + isophthalyl-CoA [RN:
R12485 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, characterized from the bacterium Syntrophorhabdus aromaticivorans, catalyses the first step in an anaerobic isophthalate degradation pathway.
History
EC 6.2.1.58 created 2019
Reference
Authors
Junghare M, Spiteller D, Schink B
Title
Anaerobic degradation of xenobiotic isophthalate by the fermenting bacterium Syntrophorhabdus aromaticivorans.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.58
ExPASy - ENZYME nomenclature database: 6.2.1.58