Entry
Name
indoleacetate---CoA ligase;
iaaB (gene name)
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
BRITE hierarchy
Sysname
(indol-3-yl)acetate:CoA ligase (AMP-forming)
Reaction(IUBMB)
ATP + (indol-3-yl)acetate + CoA = AMP + diphosphate + (indol-3-yl)acetyl-CoA [RN:
R12968 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, characterized from the bacterium Aromatoleum aromaticum, is involved in degradation of (indol-3-yl)acetate. It is also active with phenylacetate and the non-physiological compound (2-naphthyl)acetate.
History
EC 6.2.1.75 created 2022
Orthology
K25760 indoleacetate---CoA ligase
Genes
Taxonomy
Reference
Authors
Schuhle K, Nies J, Heider J.
Title
An indoleacetate-CoA ligase and a phenylsuccinyl-CoA transferase involved in anaerobic metabolism of auxin.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.75
ExPASy - ENZYME nomenclature database: 6.2.1.75