2 ATP + 2 N1-hydroxy-N1-succinylcadaverine = 2 AMP + 2 diphosphate + bisucaberin (overall reaction);
(1a) ATP + 2 N1-hydroxy-N1-succinylcadaverine = AMP + diphosphate + bisucaberin B;
(1b) ATP + bisucaberin B = AMP + diphosphate + bisucaberin
Substrate
ATP [CPD:C00002];
N1-hydroxy-N1-succinylcadaverine;
bisucaberin B
Product
AMP [CPD:C00020];
diphosphate [CPD:C00013];
bisucaberin;
bisucaberin B
Comment
Requires Mg2+. The enzyme, characterized from the bacterium Aliivibrio salmonicida, catalyses the last step in the biosynthesis of the siderophore bisucaberin. The enzyme catalyses the reaction in two steps - concatenation of two molecules of N1-hydroxy-N1-succinylcadaverine, followed by cyclization.