Entry
Name
caldariellaquinol oxidase (H+-transporting);
SoxABCD quinol oxidase;
SoxABCD complex;
quinol oxidase SoxABCD;
SoxM supercomplex;
aa3-type quinol oxidase;
aa3 quinol oxidase;
cytochrome aa3;
terminal quinol oxidase;
terminal quinol:oxygen oxidoreductase;
caldariella quinol:dioxygen oxidoreductase;
cytochrome aa3-type oxidase;
caldariellaquinol:O2 oxidoreductase (H+-transporting)
Class
Translocases;
Catalysing the translocation of protons;
Linked to oxidoreductase reactions
BRITE hierarchy
Sysname
caldariellaquinol:oxygen oxidoreductase (H+-transporting)
Reaction(IUBMB)
2 caldariellaquinol + O2 + n H+[side 1] = 2 caldariellaquinone + 2 H2O + n H+[side 2] [RN:
R10444 ]
Reaction(KEGG)
Substrate
Product
caldariellaquinone [CPD:
C20624 ];
H2O [CPD:
C00001 ];
H+[side 2]
Comment
A copper-containing cytochrome. The enzyme from thermophilic archaea is part of the terminal oxidase and catalyses the reduction of O2 to water, accompanied by the extrusion of protons across the cytoplasmic membrane.
History
EC 7.1.1.4 created 2013 as EC 1.10.3.13, transferred 2018 to EC 7.1.1.4
Orthology
K24009 cytochrome aa3-type oxidase subunit I
K24010 cytochrome aa3-type oxidase subunit II
K24011 cytochrome aa3-type oxidase subunit I/III
Genes
STO : STK_01030(soxM) STK_01350(soxA) STK_01360(soxB) STK_23950(soxA2) STK_23960(soxB2)
SOH : D1869_13125 D1869_13130 D1869_14920 D1869_15065 D1869_15070
SSO : SSO2657(soxB) SSO2658(soxA) SSO2973(soxM)
SOL : Ssol_0467 Ssol_0468 Ssol_0765
SSOA : SULA_0458 SULA_0459 SULA_0758
SSOL : SULB_0460 SULB_0461 SULB_0760
SSOF : SULC_0458 SULC_0459 SULC_0758
SSHI : J5U23_00527 J5U23_00837 J5U23_00838
SCAS : SACC_23190 SACC_23200 SACC_30720
SAI : Saci_2088 Saci_2089(soxA) Saci_2263(soxM)
SACN : SacN8_10150 SacN8_10155 SacN8_11030
SACR : SacRon12I_10400 SacRon12I_10405 SacRon12I_11275
SACS : SUSAZ_09490 SUSAZ_09495 SUSAZ_10625
SIS : LS215_2551 LS215_2816 LS215_2817
SIA : M1425_2378 M1425_2655 M1425_2656
SIM : M1627_2456 M1627_2709 M1627_2710
SID : M164_2385 M164_2640 M164_2641
SIY : YG5714_2525 YG5714_2829 YG5714_2830
SIN : YN1551_0381 YN1551_3017 YN1551_3018
SIH : SiH_2320 SiH_2609 SiH_2610
SIR : SiRe_2267 SiRe_2548 SiRe_2549
SIC : SiL_2228 SiL_2497 SiL_2498
SULA : BFU36_06815 BFU36_09060 BFU36_09065 BFU36_12355 BFU36_12360
SULE : GFS03_00780 GFS03_00785 GFS03_12785
SULO : GFS33_04675 GFS33_05980 GFS33_05985
SULL : EWF20_01435 EWF20_01585 EWF20_01590 EWF20_14170 EWF20_14175
MSE : Msed_0289 Msed_0290 Msed_0324
MEMJ : MJ1HA_0377 MJ1HA_0378 MJ1HA_0416
MCN : Mcup_1608 Mcup_1609 Mcup_1747 Mcup_1779 Mcup_1780
MHK : DFR87_04690 DFR87_05080 DFR87_05085 DFR87_05350 DFR87_05355
MPRU : DFR88_04990 DFR88_05165 DFR88_05170
MTEN : GWK48_06590 GWK48_06595 GWK48_07690 GWK48_11330 GWK48_11335
MJN : MjAS7_0913 MjAS7_0914 MjAS7_0989 MjAS7_1218 MjAS7_1219
AMAN : B6F84_01145 B6F84_01300 B6F84_01305 B6F84_04035 B6F84_04040 B6F84_05705
ABRI : DFR85_00030 DFR85_00035 DFR85_00215 DFR85_00220 DFR85_00255 DFR85_13685
ASUL : DFR86_01170 DFR86_01295 DFR86_01300 DFR86_03935 DFR86_03940 DFR86_04800
ACIH : HS5_06620 HS5_06630 HS5_16060 HS5_16070
SACD : HS1genome_1391 HS1genome_1392 HS1genome_1398
CSTY : KN1_02430 KN1_02440 KN1_08990 KN1_23000 KN1_23010
STEP : IC006_0695 IC006_2114 IC006_2115 IC006_2153 IC006_2154
SMET : RQ359_002081(soxA) RQ359_002082(soxB) RQ359_002120(soxA)
SAHS : HS7_01640 HS7_01650
» show all
Taxonomy
Reference
Authors
Gleissner M, Kaiser U, Antonopoulos E, Schafer G
Title
The archaeal SoxABCD complex is a proton pump in Sulfolobus acidocaldarius.
Journal
Reference
Authors
Purschke WG, Schmidt CL, Petersen A, Schafer G
Title
The terminal quinol oxidase of the hyperthermophilic archaeon Acidianus ambivalens exhibits a novel subunit structure and gene organization.
Journal
Reference
Authors
Gilderson G, Aagaard A, Gomes CM, Adelroth P, Teixeira M, Brzezinski P
Title
Kinetics of electron and proton transfer during O(2) reduction in cytochrome aa(3) from A. ambivalens: an enzyme lacking Glu(I-286).
Journal
Reference
Authors
Komorowski L, Verheyen W, Schafer G
Title
The archaeal respiratory supercomplex SoxM from S. acidocaldarius combines features of quinole and cytochrome c oxidases.
Journal
Reference
Authors
Muller FH, Bandeiras TM, Urich T, Teixeira M, Gomes CM, Kletzin A
Title
Coupling of the pathway of sulphur oxidation to dioxygen reduction: characterization of a novel membrane-bound thiosulphate:quinone oxidoreductase.
Journal
Reference
Authors
Bandeiras TM, Pereira MM, Teixeira M, Moenne-Loccoz P, Blackburn NJ
Title
Structure and coordination of CuB in the Acidianus ambivalens aa3 quinol oxidase heme-copper center.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 7.1.1.4
ExPASy - ENZYME nomenclature database: 7.1.1.4
BRENDA, the Enzyme Database: 7.1.1.4