KEGG   ENZYME: 7.2.2.15
Entry
EC 7.2.2.15                 Enzyme                                 
Name
P-type Ag+ transporter;
Ag+-exporting ATPase
Class
Translocases;
Catalysing the translocation of inorganic cations;
Linked to the hydrolysis of a nucleoside triphosphate
Sysname
ATP phosphohydrolase (P-type, Ag+-exporting)
Reaction(IUBMB)
ATP + H2O + Ag+[side 1] = ADP + phosphate + Ag+[side 2]
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
Ag+[side 1]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
Ag+[side 2]
Comment
A P-type ATPase that exports Ag+ ions from some bacteria, archaea as well as from some animal tissues. The proteins also transport Cu+ ions (cf. EC 7.2.2.8, P-type Cu+ transporter).
History
EC 7.2.2.15 created 2000 as EC 3.6.3.53, transferred 2018 to EC 7.2.2.15
Orthology
K23254  P-type Ag+ transporter
Genes
ESL: O3K_01545
ESO: O3O_24100
ESM: O3M_01590
ECK: EC55989_3910(silP)
ELH: ETEC_0224
ECV: APECO1_O1R116(silP)
ECL: EcolC_3420
ELP: P12B_c3605(silP)
SENH: CFSAN002069_14200
SEEC: CFSAN002050_22065
SENC: SEET0819_01575
ENC: ECL_04885 ECL_A028
ECLE: ECNIH2_22210
ECLN: ECNIH4_01590
ECLI: ECNIH5_22410
ECLX: LI66_21485
ECLY: LI62_23505
ECLZ: LI64_20590
EHM: AB284_03340
ECLC: ECR091_23065
EKB: BFV64_23730
ECLS: LI67_022975
ECHG: FY206_23090(silP)
ENX: NI40_012330
END: A4308_05725
ENZ: G0034_21635(silP)
ENS: HWQ15_06820(silP)
ESA: ESA_04245
CSJ: CSK29544_3p0034
CSI: P262_p2070
CMJ: AFK66_020390
CTU: Ctu_3p00600(silP)
KPN: KPN_pKPN3p05945(silP)
KPU: KP1_p145(silP)
KPH: KPNIH24_27735
KPZ: KPNIH27_27870
KPV: KPNIH29_27290
KPY: KPNIH31_26300
KPG: KPNIH32_28730
KPC: KPNIH10_27070
KPO: KPN2242_25446
KPJ: N559_5295
KPA: KPNJ1_05574
KPX: PMK1_a00110(silP)
KPNE: KU54_00340
KPNU: LI86_27195
KOM: HR38_28340
KOK: KONIH1_29550
KOC: AB185_02350
KQU: AVR78_26350
KQV: B8P98_27970
KLW: DA718_29665(silP)
KGR: JJJ10_28570(silP)
RTG: NCTC13098_04593(actP_1)
CFD: CFNIH1_01975
CWE: CO701_01880
CSED: JY391_01240(silP)
CAMA: F384_23500
CAF: AL524_01700
CIR: C2U53_08300
CIE: AN232_02045
CTEL: GBC03_26455(silP)
CARS: E1B03_00520(silP)
LEI: C2U54_25110
LEH: C3F35_24465
LEE: DVA44_25385
KIN: AB182_01365 AB182_01725
PDZ: HHA33_25710(silP)
METY: MRY16398_p10100 MRY16398_p11080
PVJ: LMA04_09045(silP)
SUPE: P0H77_18265(silP)
TOE: QMG90_03880(silP)
EBC: C2U52_01690
YEE: YE5303_30421
YCA: F0T03_02185
YKI: HRD70_06600
SNEV: OI978_27415(silP)
RIU: I2123_03990(cadA)
CARU: P0E69_02090(silP)
PANP: PSNIH2_23070
SPC: Sputcn32_0264
SHN: Shewana3_4302
SDEO: D0436_24285(silP)
MMAF: GCM100_02530
ASAA: KXJ75_06325(silP)
AALM: LUX29_12290
DBK: DGMP_03980
NANN: O0S08_24185
TED: U5C87_12560
PROP: QQ658_06080
OLE: K0B96_13145(cadA) K0B96_16280
ELUT: CKA38_07445
SMAM: Mal15_55620(silP_2)
SNEP: Enr13x_73950(silP_3)
ACAF: CA12_15210(silP)
SAHN: JRG66_09620
CBAU: H1R16_01805
 » show all
Reference
1  [PMID:9930866]
  Authors
Gupta A, Matsui K, Lo JF, Silver S
  Title
Molecular basis for resistance to silver cations in Salmonella.
  Journal
Nat Med 5:183-8 (1999)
DOI:10.1038/5545
  Sequence
[ag:AAD11750]
Reference
2  [PMID:10448119]
  Authors
Bury NR, Grosell M, Grover AK, Wood CM.
  Title
ATP-dependent silver transport across the basolateral membrane of rainbow trout gills.
  Journal
Toxicol Appl Pharmacol 159:1-8 (1999)
DOI:10.1006/taap.1999.8706
Other DBs
ExplorEnz - The Enzyme Database: 7.2.2.15
IUBMB Enzyme Nomenclature: 7.2.2.15
ExPASy - ENZYME nomenclature database: 7.2.2.15
BRENDA, the Enzyme Database: 7.2.2.15

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Gene (233)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (102)   
   KEGG MGENES (130)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
DNA sequence (377)   
   GenBank (203)   
   EMBL (174)   
Protein domain (11)   
   InterPro (11)   
All databases (623)   

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