KEGG ENZYME: 7.5.2.1

ENZYME: 7.5.2.1

Entry

EC 7.5.2.1                  Enzyme

Name

ABC-type maltose transporter;
maltose ABC transporter;
maltose-transporting ATPase

Class

Translocases;
Catalysing the translocation of carbohydrates and their derivatives;
Linked to the hydrolysis of a nucleoside triphosphate

Sysname

ATP phosphohydrolase (ABC-type, maltose-importing)

Reaction(IUBMB)

ATP + H2O + maltose-[maltose-binding protein][side 1] = ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]

Substrate

ATP [CPD:C00002];
H2O [CPD:C00001];
maltose-[maltose-binding protein][side 1]

Product

ADP [CPD:C00008];
phosphate [CPD:C00009];
maltose[side 2];
[maltose-binding protein][side 1]

Comment

An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme, found in bacteria, interacts with an extracytoplasmic substrate binding protein and mediates the import of maltose and maltose oligosaccharides.

History

EC 7.5.2.1 created 2000 as EC 3.6.3.19, transferred 2018 to EC 7.5.2.1

Reference

1 [PMID:1282354]

Authors

Higgins CF.

Title

ABC transporters: from microorganisms to man.

Journal

Annu Rev Cell Biol 8:67-113 (1992)
DOI:10.1146/annurev.cb.08.110192.000435

Reference

2 [PMID:8437518]

Authors

Dassa E, Muir S.

Title

Membrane topology of MalG, an inner membrane protein from the maltose transport system of Escherichia coli.

Journal

Mol Microbiol 7:29-38 (1993)
DOI:10.1111/j.1365-2958.1993.tb01094.x

Sequence

[eco:b4034 b4033 b4032 b4035]

Reference

3 [PMID:7569321]

Authors

Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr.

Title

Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases.

Journal

Res Microbiol 146:271-8 (1995)
DOI:10.1016/0923-2508(96)81050-3

Reference

4 [PMID:9889977]

Authors

Saier MH Jr.

Title

Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya.

Journal

Adv Microb Physiol 40:81-136 (1998)
DOI:10.1016/s0065-2911(08)60130-7

Reference

Authors

Griffiths, J.K. and Sansom, C.E.

Title

The Transporter Factsbook, Academic Press, San Diego, 1998

Other DBs

ExplorEnz - The Enzyme Database:

7.5.2.1

IUBMB Enzyme Nomenclature:

7.5.2.1

ExPASy - ENZYME nomenclature database:

7.5.2.1

BRENDA, the Enzyme Database:

7.5.2.1

All links

Protein sequence (16483)   
   UniProt (27)   
   SWISS-PROT (27)   
   RefSeq(pep) (16429)   
DNA sequence (120889)   
   RefSeq(nuc) (110424)   
   GenBank (5661)   
   EMBL (4804)   
Protein domain (10)   
   InterPro (10)   
All databases (137382)   

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