KEGG   Escherichia coli K-12 MG1655: b0184
Entry
b0184             CDS       T00007                                 
Symbol
dnaE
Name
(RefSeq) DNA polymerase III subunit alpha
  KO
K02337  DNA polymerase III subunit alpha [EC:2.7.7.7]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco03030  DNA replication
eco03430  Mismatch repair
eco03440  Homologous recombination
Brite
KEGG Orthology (KO) [BR:eco00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    b0184 (dnaE)
   03430 Mismatch repair
    b0184 (dnaE)
   03440 Homologous recombination
    b0184 (dnaE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:eco03032]
    b0184 (dnaE)
   03400 DNA repair and recombination proteins [BR:eco03400]
    b0184 (dnaE)
Enzymes [BR:eco01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     b0184 (dnaE)
DNA replication proteins [BR:eco03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    DNA polymerase III holoenzyme
     b0184 (dnaE)
DNA repair and recombination proteins [BR:eco03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    DNA polymerase III holoenzyme
     b0184 (dnaE)
SSDB
Motif
Pfam: DNA_pol3_alpha DNA_pol3_finger PHP DNA_pol_IIIA_C HHH_6 tRNA_anti-codon
Other DBs
NCBI-GeneID: 944877
NCBI-ProteinID: NP_414726
Pasteur: dnaE
RegulonDB: ECK120000232
ECOCYC: EG10238
ASAP: ABE-0000624
UniProt: P10443
Structure
Position
205126..208608
AA seq 1160 aa
MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDFTNLCGLVKFYGAGHGA
GIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIDRDW
LIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEEHFPDRYFLELIRTGRPDEES
YLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVAIHDGFTLDDPKRPRNYSPQQYM
RSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEYFLPQFPTGDMSTEDYLVKRAKEGL
EERLAFLFPDEEERLKRRPEYDERLETELQVINQMGFPGYFLIVMEFIQWSKDNGVPVGP
GRGSGAGSLVAYALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDQVIEHVAD
MYGRDAVSQIITFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPPDPGMTLAKAFEAEPQ
LPEIYEADEEVKALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQ
FDKSDVEYAGLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLDDKKSFDML
QRSETTAVFQLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREE
ISYPDVQWQHESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEM
AKQRSVFAEGAEKNGINAELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPA
EFMAAVMTADMDNTEKVVGLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKG
VGEGPIEAIIEARNKGGYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMN
SLGDALKAADQHAKAEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLY
LTGHPINQYLKEIERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLD
DRSGRLEVMLFTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKY
ARGLAISLTDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSD
RLLNDLRGLIGSEQVELEFD
NT seq 3483 nt   +upstreamnt  +downstreamnt
atgtctgaaccacgtttcgtacacctgcgggtgcacagcgactactcgatgatcgatggc
ctggccaaaaccgcaccgttggtaaaaaaggcggcggcgttgggtatgccagcactggcg
atcaccgatttcaccaacctttgtggtctggtgaagttctacggagcgggacatggcgca
gggattaagcctatcgtcggggcagattttaacgtccagtgcgacctgctgggtgatgag
ttaacccacctgacggtactggcggcgaacaataccggctatcagaatctgacgttgctg
atctcaaaagcgtatcagcgcgggtacggtgccgccgggccgatcatcgatcgcgactgg
cttatcgaattaaacgaagggttgatccttctttccggcggacgcatgggcgacgtcgga
cgcagtcttttgcgtggtaacagcgcgctggtagatgagtgtgtcgcgttttatgaagaa
cacttcccggatcgctattttctcgagctgatccgcaccggcaggccggatgaagaaagc
tatctgcacgcggcggtggaactggcggaagcgcgcggtttgcccgtcgtggcgaccaac
gacgtgcgctttatcgacagcagcgactttgacgcacacgaaatccgcgtcgcgatccac
gacggctttaccctcgacgatcctaaacgcccgcgtaactattcgccgcagcaatatatg
cgtagcgaagaggagatgtgtgagctgtttgccgacatccccgaagcccttgccaacacc
gttgagatcgccaaacgctgtaacgtaaccgtgcgtcttggtgaatacttcctgccgcag
ttcccgaccggggacatgagcaccgaagattatctggtcaagcgtgcaaaagagggcctg
gaagagcgtctggcctttttattccctgatgaggaagaacgtcttaagcgccgcccggaa
tatgacgaacgtctggagactgaacttcaggttatcaaccagatgggcttcccgggctac
ttcctcatcgttatggaatttatccagtggtcgaaagataacggcgtaccggtagggcca
ggccgtggctccggtgcgggttcactggtggcctacgcgctgaaaatcaccgacctcgat
ccgctggaatttgacctgctgttcgaacgtttccttaacccggaacgtgtctccatgcct
gacttcgacgttgacttctgtatggagaaacgcgatcaggttatcgagcacgtagcggac
atgtacggtcgtgatgcggtatcgcagatcatcaccttcggtacaatggcggcgaaagcg
gtgatccgcgacgtaggccgcgtgctggggcatccgtacggctttgtcgatcgtatctcg
aaactgatcccgcccgatccggggatgacgctggcgaaagcgtttgaagccgagccgcag
ctgccggaaatctacgaagcggatgaagaagttaaggcgctgatcgacatggcgcgcaaa
ctggaaggggtcacccgtaacgccggtaagcacgccggtggggtggttatcgcgccgacc
aaaattaccgattttgcgccgctttactgcgatgaagagggcaaacatccggtcacccag
tttgataaaagcgacgttgaatacgccggactggtgaagttcgacttccttggtttgcgt
acgctcaccatcatcaactgggcgctggagatgatcaacaagcggcgggcgaagaatggc
gagccgccgctggatatcgctgcgatcccgctggatgataagaaaagcttcgacatgctg
caacgctcggaaaccacggcggtattccagcttgaatcgcgcggcatgaaggacctgatc
aagcgtctacaacctgactgcttcgaagatatgatcgccctagtggcactgttccgcccc
ggtccgttgcaatcagggatggtggataactttatcgaccgtaaacatggtcgtgaagag
atctcctatccggacgtacagtggcagcatgaaagcctgaaaccggtactggagccaacc
tacggcattatcctgtatcaggaacaggtcatgcagattgcgcaggtgctttctggttat
accctcggtggcgcggatatgctgcgtcgtgcgatgggtaagaaaaagccggaagagatg
gctaagcaacgttctgtatttgctgaaggtgcagaaaagaacggaatcaacgctgaactg
gcgatgaaaatcttcgacctggtggagaaattcgctggttacggatttaacaaatcgcac
tctgcggcctatgctttggtgtcatatcaaacgttatggctgaaagcgcactatcctgcg
gagtttatggcggcggtaatgaccgccgatatggacaacaccgagaaggtggtgggtctg
gtggatgagtgctggcggatggggctgaaaatcctgccaccagatataaactccggtctt
taccatttccacgtcaacgacgacggcgaaatcgtgtatggtattggcgcgatcaaaggg
gtcggtgaaggtccgattgaggccatcatcgaagcccgtaataaaggcggctacttccgc
gaactgtttgatctctgcgcccgtaccgacaccaaaaagttgaaccgtcgcgtgctggaa
aaactgatcatgtccggggcgtttgaccgtcttgggccacatcgcgcagcgctgatgaac
tcgctgggcgatgcgttaaaagcggcagatcaacacgcgaaagcggaagctatcggtcag
gccgatatgttcggcgtgctggccgaagagccggaacaaattgaacaatcctacgccagc
tgccaaccgtggccggagcaggtggtattagatggggaacgtgaaacgttaggcctgtac
ctgaccggacaccctatcaaccagtatttaaaagagattgagcgttatgtcggaggcgta
aggctgaaagacatgcacccgacagaacgtggtaaagtcatcacggctgcggggctcgtt
gttgccgcgcgggttatggtcaccaagcgcggcaatcgtatcggtatctgcacgctggat
gaccgttccgggcggctggaagtgatgttgtttactgacgccctggataaataccagcaa
ttgctggaaaaagaccgcatacttatcgtcagcggacaggtcagctttgatgacttcagc
ggtgggcttaaaatgaccgctcgcgaagtgatggatattgacgaagcccgggaaaaatat
gctcgcgggcttgctatctcgctgacggacaggcaaattgatgaccagcttttaaaccga
ctccgtcagtctctggaaccccaccgctctgggacaattccagtacatctctactatcag
agggcggatgcacgcgcgcggttgcgttttggcgcgacgtggcgtgtctctccgagcgat
cgtttattaaacgatctccgtggcctcattggttcggagcaggtggaactggagtttgac
taa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (9)   
   PDB (9)   
Protein domain (6)   
   Pfam (6)   
All databases (40)   

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