KEGG   Escherichia coli K-12 MG1655: b0243
Entry
b0243             CDS       T00007                                 
Symbol
proA
Name
(RefSeq) glutamate-5-semialdehyde dehydrogenase
  KO
K00147  glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00330  Arginine and proline metabolism
eco00332  Carbapenem biosynthesis
eco01100  Metabolic pathways
eco01110  Biosynthesis of secondary metabolites
eco01230  Biosynthesis of amino acids
Module
eco_M00015  Proline biosynthesis, glutamate => proline
Brite
KEGG Orthology (KO) [BR:eco00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    b0243 (proA)
  09110 Biosynthesis of other secondary metabolites
   00332 Carbapenem biosynthesis
    b0243 (proA)
Enzymes [BR:eco01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.41  glutamate-5-semialdehyde dehydrogenase
     b0243 (proA)
SSDB
Motif
Pfam: Aldedh DUF1487
Other DBs
NCBI-GeneID: 946680
NCBI-ProteinID: NP_414778
Pasteur: proA
RegulonDB: ECK120000758
ECOCYC: EG10767
ASAP: ABE-0000832
UniProt: P07004
Position
261503..262756
AA seq 417 aa
MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNANAQDVADARANGLSE
AMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYE
ARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPD
RALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESVEIAEALK
VIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAK
VVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVD
SSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
NT seq 1254 nt   +upstreamnt  +downstreamnt
atgctggaacaaatgggcattgccgcgaagcaagcctcgtataaattagcgcaactctcc
agccgcgaaaaaaatcgcgtgctggaaaaaatcgccgatgaactggaagcacaaagcgaa
atcatcctcaacgctaacgcccaggatgttgctgacgcgcgagccaatggccttagcgaa
gcgatgcttgaccgtctggcactgacgcccgcacggctgaaaggcattgccgacgatgta
cgtcaggtgtgcaacctcgccgatccggtggggcaggtaatcgatggcggcgtactggac
agcggcctgcgtcttgagcgtcgtcgcgtaccgctgggggttattggcgtgatttatgaa
gcgcgcccgaacgtgacggttgatgtcgcttcgctgtgcctgaaaaccggtaatgcggtg
atcctgcgcggtggcaaagaaacgtgtcgcactaacgctgcaacggtggcggtgattcag
gacgccctgaaatcctgcggcttaccggcgggtgccgtgcaggcgattgataatcctgac
cgtgcgctggtcagtgaaatgctgcgtatggataaatacatcgacatgctgatcccgcgt
ggtggcgctggtttgcataaactgtgccgtgaacagtcgacaatcccggtgatcacaggt
ggtataggcgtatgccatatttacgttgatgaaagtgtagagatcgctgaagcattaaaa
gtgatcgtcaacgcgaaaactcagcgtccgagcacatgtaatacggttgaaacgttgctg
gtgaataaaaacatcgccgatagcttcctgcccgcattaagcaaacaaatggcggaaagc
ggcgtgacattacacgcagatgcagctgcactggcgcagttgcaggcaggccctgcgaag
gtggttgctgttaaagccgaagagtatgacgatgagtttctgtcattagatttgaacgtc
aaaatcgtcagcgatcttgacgatgccatcgcccatattcgtgaacacggcacacaacac
tccgatgcgatcctgacccgcgatatgcgcaacgcccagcgttttgttaacgaagtggat
tcgtccgctgtttacgttaacgcctctacgcgttttaccgacggcggccagtttggtctg
ggtgcggaagtggcggtaagcacacaaaaactccacgcgcgtggcccaatggggctggaa
gcactgaccacttacaagtggatcggcattggtgattacaccattcgtgcgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (36)   

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