KEGG   Escherichia coli K-12 MG1655: b0642
Entry
b0642             CDS       T00007                                 
Symbol
leuS
Name
(RefSeq) leucine--tRNA ligase
  KO
K01869  leucyl-tRNA synthetase [EC:6.1.1.4]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00970  Aminoacyl-tRNA biosynthesis
Brite
KEGG Orthology (KO) [BR:eco00001]
 09120 Genetic Information Processing
  09122 Translation
   00970 Aminoacyl-tRNA biosynthesis
    b0642 (leuS)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:eco01007]
    b0642 (leuS)
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:eco03016]
    b0642 (leuS)
   03029 Mitochondrial biogenesis [BR:eco03029]
    b0642 (leuS)
Enzymes [BR:eco01000]
 6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.1  Ligases forming aminoacyl-tRNA and related compounds
    6.1.1.4  leucine---tRNA ligase
     b0642 (leuS)
Amino acid related enzymes [BR:eco01007]
 Aminoacyl-tRNA synthetase
  Class I (U)
   b0642 (leuS)
Transfer RNA biogenesis [BR:eco03016]
 Eukaryotic type
  Aminoacyl-tRNA synthetases (AARSs)
   Multi-aminoacyl-tRNA synthetase complex (MSC)
    b0642 (leuS)
 Prokaryotic type
    b0642 (leuS)
Mitochondrial biogenesis [BR:eco03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial transcription and translation factors
   Other mitochondrial DNA transcription and translation factors
    b0642 (leuS)
SSDB
Motif
Pfam: tRNA-synt_1_2 tRNA-synt_1 tRNA-synt_1g Anticodon_1 tRNA-synt_1f tRNA-synt_1e
Other DBs
NCBI-GeneID: 947497
NCBI-ProteinID: NP_415175
Pasteur: leuS
RegulonDB: ECK120000525
ECOCYC: EG10532
ASAP: ABE-0002196
UniProt: P07813
Structure
Position
complement(672201..674783)
AA seq 860 aa
MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGD
VIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYD
WSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCD
TKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYD
NTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEK
KGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVI
LAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDW
GVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG
MPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLY
FRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGR
IVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQE
SGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQ
TFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEG
DIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLD
GVTVRKVIYVPGKLLNLVVG
NT seq 2583 nt   +upstreamnt  +downstreamnt
atgcaagagcaataccgcccggaagagatagaatccaaagtacagcttcattgggatgag
aagcgcacatttgaagtaaccgaagacgagagcaaagagaagtattactgcctgtctatg
cttccctatccttctggtcgactacacatgggccacgtacgtaactacaccatcggtgac
gtgatcgcccgctaccagcgtatgctgggcaaaaacgtcctgcagccgatcggctgggac
gcgtttggtctgcctgcggaaggcgcggcggtgaaaaacaacaccgctccggcaccgtgg
acgtacgacaacatcgcgtatatgaaaaaccagctcaaaatgctgggctttggttatgac
tggagccgcgagctggcaacctgtacgccggaatactaccgttgggaacagaaattcttc
accgagctgtataaaaaaggcctggtatataagaagacttctgcggtcaactggtgcccg
aacgaccagaccgtactggcgaacgaacaagttatcgacggctgctgctggcgctgcgat
accaaagttgaacgtaaagagatcccgcagtggtttatcaaaatcactgcttacgctgac
gagctgctcaacgatctggataaactggatcactggccagacaccgttaaaaccatgcag
cgtaactggatcggtcgttccgaaggcgtggagatcaccttcaacgttaacgactatgac
aacacgctgaccgtttacactacccgcccggacacctttatgggttgtacctacctggcg
gtagctgcgggtcatccgctggcgcagaaagcggcggaaaataatcctgaactggcggcc
tttattgacgaatgccgtaacaccaaagttgccgaagctgaaatggcgacgatggagaaa
aaaggcgtcgatactggctttaaagcggttcacccattaacgggcgaagaaattcccgtt
tgggcagcaaacttcgtattgatggagtacggcacgggcgcagttatggcggtaccgggg
cacgaccagcgcgactacgagtttgcctctaaatacggcctgaacatcaaaccggttatc
ctggcagctgacggctctgagccagatctttctcagcaagccctgactgaaaaaggcgtg
ctgttcaactctggcgagttcaacggtcttgaccatgaagcggccttcaacgccatcgcc
gataaactgactgcgatgggcgttggcgagcgtaaagtgaactaccgcctgcgcgactgg
ggtgtttcccgtcagcgttactggggcgcgccgattccgatggtgacgctggaagacggt
accgtaatgccgaccccggacgaccagctgccggtgatcctgccggaagatgtggtaatg
gacggcattaccagcccgattaaagcagatccggagtgggcgaaaactaccgttaacggt
atgccagcactgcgtgaaaccgacactttcgacacctttatggagtcctcctggtactat
gcgcgctacacttgcccgcagtacaaagaaggtatgctggattccgaagcggctaactac
tggctgccggtggatatctacattggtggtattgaacacgccattatgcacctgctctac
ttccgcttcttccacaaactgatgcgtgatgcaggcatggtgaactctgacgaaccagcg
aaacagttgctgtgtcagggtatggtgctggcagatgccttctactatgttggcgaaaac
ggcgaacgtaactgggtttccccggttgatgctatcgttgaacgtgacgagaaaggccgt
atcgtgaaagcgaaagatgcggcaggccatgaactggtttataccggcatgagcaaaatg
tccaagtcgaagaacaacggtatcgacccgcaggtgatggttgaacgttacggcgcggac
accgttcgtctgtttatgatgtttgcttctccggctgatatgactctcgaatggcaggaa
tccggtgtggaaggggctaaccgcttcctgaaacgtgtctggaaactggtttacgagcac
acagcaaaaggtgatgttgcggcactgaacgttgatgcgctgactgaaaatcagaaagcg
ctgcgtcgcgatgtgcataaaacgatcgctaaagtgaccgatgatatcggccgtcgtcag
accttcaacaccgcaattgcggcgattatggagctgatgaacaaactggcgaaagcacca
accgatggcgagcaggatcgcgctctgatgcaggaagcactgctggccgttgtccgtatg
cttaacccgttcaccccgcacatctgcttcacgctgtggcaggaactgaaaggcgaaggc
gatatcgacaacgcgccgtggccggttgctgacgaaaaagcgatggtggaagactccacg
ctggtcgtggtgcaggttaacggtaaagtccgtgccaaaatcaccgttccggtggacgca
acggaagaacaggttcgcgaacgtgctggccaggaacatctggtagcaaaatatcttgat
ggcgttactgtacgtaaagtgatttacgtaccaggtaaactcctcaatctggtcgttggc
taa

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (16)   
   PDB (16)   
Protein domain (6)   
   Pfam (6)   
All databases (54)   

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