KEGG   Escherichia coli K-12 MG1655: b2234
Entry
b2234             CDS       T00007                                 
Symbol
nrdA
Name
(RefSeq) ribonucleoside-diphosphate reductase 1 subunit alpha
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00230  Purine metabolism
eco00240  Pyrimidine metabolism
eco01100  Metabolic pathways
eco01232  Nucleotide metabolism
Module
eco_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
eco_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:eco00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    b2234 (nrdA)
   00240 Pyrimidine metabolism
    b2234 (nrdA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:eco03400]
    b2234 (nrdA)
Enzymes [BR:eco01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     b2234 (nrdA)
DNA repair and recombination proteins [BR:eco03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    b2234 (nrdA)
SSDB
Motif
Pfam: Ribonuc_red_lgC Ribonuc_red_lgN ATP-cone
Other DBs
NCBI-GeneID: 946612
NCBI-ProteinID: NP_416737
Pasteur: nrdA
RegulonDB: ECK120000653
ECOCYC: EG10660
ASAP: ABE-0007383
UniProt: P00452
Structure
Position
2344865..2347150
AA seq 761 aa
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHE
TIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLL
EDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACL
FSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINAT
SSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGG
AATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSD
VPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHC
NTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEE
LAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLT
HKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWE
ALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYE
HLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLT
AYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
NT seq 2286 nt   +upstreamnt  +downstreamnt
atgaatcagaatctgctggtgacaaagcgcgacggtagcacagagcgcatcaatctcgac
aaaatccatcgcgttctggattgggcggcagaaggactgcataacgtttcgatttcccag
gtcgagctgcgctcccacattcagttttatgacggtatcaagacctctgacatccacgaa
accattatcaaggctgccgcagacctgatctcccgtgatgcgccggattatcagtatctc
gccgcgcgcctggcgatcttccacctgcgtaaaaaagcctacggccagtttgagccgcct
gcgctgtacgaccacgtggtgaaaatggtcgagatgggcaaatacgataatcatctgctg
gaagactacacggaagaagagttcaagcagatggacacctttatcgatcacgaccgtgat
atgaccttctcttatgctgccgttaagcagctggaaggcaaatatctggtacagaaccgc
gtgaccggcgaaatctatgagagcgcccagttcctttatattctagttgccgcgtgcttg
ttctcgaactacccgcgtgaaacgcgcctgcaatatgtgaagcgtttttacgacgcggtt
tccacatttaaaatttcgctgccgacgccaatcatgtccggcgtgcgtaccccgactcgt
cagttcagctcctgcgtactgatcgagtgcggtgacagcctggattccatcaacgccacc
tccagcgcgattgttaaatacgtttcccagcgtgccgggatcggcatcaacgccgggcgt
attcgtgcgctgggtagcccgattcgcggtggtgaagcgttccataccggctgcattccg
ttctacaaacatttccagacagcggtgaaatcctgctctcagggcggtgtgcgcggcggt
gcggcaacgctgttctacccgatgtggcatctggaagtggaaagcctgctggtgttgaaa
aacaaccgtggtgtggaaggcaaccgcgtgcgtcatatggactacggggtacaaatcaac
aaactgatgtatacccgtctgctgaaaggtgaagatatcaccctgttcagcccgtccgac
gtaccggggctgtacgacgcgttcttcgccgatcaggaagagtttgaacgtctgtatacc
aaatatgagaaagacgacagcatccgcaagcagcgtgtgaaagccgttgagctgttctcg
ctgatgatgcaggaacgtgcgtctaccggtcgtatctatattcagaacgttgaccactgc
aatacccatagcccgtttgatccggccatcgcgccagtgcgtcagtctaacctgtgcctg
gagatagccctgccgaccaaaccgctgaacgacgtcaacgacgagaacggtgaaatcgcg
ctgtgtacgctgtctgctttcaacctgggcgcaattaataacctggatgaactggaagag
ctggcaattctggcggttcgtgcacttgacgcgctgctggattatcaggattacccgatc
ccggccgccaaacgtggagcgatgggtcgtcgtacgctgggtattggtgtgatcaacttc
gcttactacctggcgaagcacggtaaacgctactccgacggcagcgccaacaacctgacg
cataaaaccttcgaagccattcagtattacctgctgaaagcctctaatgagctggcgaaa
gagcaaggcgcgtgcccgtggtttaacgaaaccacttacgcgaaagggatcctgccgatc
gatacctataagaaagatctggataccatcgctaatgagccgctgcattacgactgggaa
gctctgcgtgagtcaatcaaaacgcacggtctgcgtaactccacgctttctgctctgatg
ccgtccgagacttcttcgcagatctctaacgccactaacggtattgaaccgccgcgcggt
tacgtcagcatcaaagcgtcgaaagacggtattttgcgccaggtggtgccggactacgag
cacctgcacgacgcctatgagctgctgtgggaaatgccgggtaacgatggttatctgcaa
ctggtgggtatcatgcagaaatttatcgatcagtcgatctctgccaacaccaactacgat
ccgtcacgcttcccgtcaggaaaagtgccgatgcagcagttgctgaaagacctgctcacc
gcctacaaattcggggtcaaaacactgtattatcagaacacccgtgacggcgctgaagac
gcacaagacgatctggtgccgtcaatccaggacgatggctgcgaaagcggcgcatgtaag
atctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (27)   
   PDB (27)   
Protein domain (3)   
   Pfam (3)   
All databases (75)   

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