KEGG T00007: b2661

Escherichia coli K-12 MG1655: b2661

Entry

b2661             CDS       T00007

Symbol

gabD

Name

(RefSeq) succinate-semialdehyde dehydrogenase (NADP(+)) GabD

K00135

succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]

Organism

eco Escherichia coli K-12 MG1655

Pathway

eco00250

Alanine, aspartate and glutamate metabolism

eco00310

Lysine degradation

eco00350

Tyrosine metabolism

eco00650

Butanoate metabolism

eco00760

Nicotinate and nicotinamide metabolism

eco01100

Metabolic pathways

eco01120

Microbial metabolism in diverse environments

Module

eco_M00027

GABA (gamma-Aminobutyrate) shunt

eco_M00956

Lysine degradation, bacteria, L-lysine => succinate

Brite

KEGG Orthology (KO) [BR:eco00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    b2661 (gabD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    b2661 (gabD)
   00310 Lysine degradation
    b2661 (gabD)
   00350 Tyrosine metabolism
    b2661 (gabD)
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    b2661 (gabD)
Enzymes [BR:eco01000]
1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.16  succinate-semialdehyde dehydrogenase [NAD(P)+]
     b2661 (gabD)
    1.2.1.20  glutarate-semialdehyde dehydrogenase
     b2661 (gabD)
    1.2.1.79  succinate-semialdehyde dehydrogenase (NADP+)
     b2661 (gabD)

SSDB

Motif

Pfam:

Aldedh

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Pasteur:

RegulonDB:

ECOCYC:

ASAP:

UniProt:

Structure

Position

2791273..2792721

AA seq 482 aa
MKLNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRA
LPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA
EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK
PASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQ
LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDG
VYDRFAEKLQQAVSKLHIGDGLDNGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKA
HERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYA
RDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCI
GL

NT seq 1449 nt +upstreamnt +downstreamnt
atgaaacttaacgacagtaacttattccgccagcaggcgttgattaacggggaatggctg
gacgccaacaatggtgaagccatcgacgtcaccaatccggcgaacggcgacaagctgggt
agcgtgccgaaaatgggcgcggatgaaacccgcgccgctatcgacgccgccaaccgcgcc
ctgcccgcctggcgcgcgctcaccgccaaagaacgcgccaccattctgcgcaactggttc
aatttgatgatggagcatcaggacgatttagcgcgcctgatgaccctcgaacagggtaaa
ccactggccgaagcgaaaggcgaaatcagctacgccgcctcctttattgagtggtttgcc
gaagaaggcaaacgcatttatggcgacaccattcctggtcatcaggccgataaacgcctg
attgttatcaagcagccgattggcgtcaccgcggctatcacgccgtggaacttcccggcg
gcgatgattacccgcaaagccggtccggcgctggcagcaggctgcaccatggtgctgaag
cccgccagtcagacgccgttctctgcgctggcgctggcggagctggcgatccgcgcgggc
gttccggctggggtatttaacgtggtcaccggttcggcgggcgcggtcggtaacgaactg
accagtaacccgctggtgcgcaaactgtcgtttaccggttcgaccgaaattggccgccag
ttaatggaacagtgcgcgaaagacatcaagaaagtgtcgctggagctgggcggtaacgcg
ccgtttatcgtctttgacgatgccgacctcgacaaagccgtggaaggcgcgctggcctcg
aaattccgcaacgccgggcaaacctgcgtctgcgccaaccgcctgtatgtgcaggacggc
gtgtatgaccgttttgccgaaaaattgcagcaggcagtgagcaaactgcacatcggcgac
gggctggataacggcgtcaccatcgggccgctgatcgatgaaaaagcggtagcaaaagtg
gaagagcatattgccgatgcgctggagaaaggcgcgcgcgtggtttgcggcggtaaagcg
cacgaacgcggcggcaacttcttccagccgaccattctggtggacgttccggccaacgcc
aaagtgtcgaaagaagagacgttcggccccctcgccccgctgttccgctttaaagatgaa
gctgatgtgattgcgcaagccaatgacaccgagtttggccttgccgcctatttctacgcc
cgtgatttaagccgcgtcttccgcgtgggcgaagcgctggagtacggcatcgtcggcatc
aataccggcattatttccaatgaagtggccccgttcggcggcatcaaagcctcgggtctg
ggtcgtgaaggttcgaagtatggcatcgaagattacttagaaatcaaatatatgtgcatc
ggtctttaa

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