KEGG   ENZYME: 1.1.1.138
Entry
EC 1.1.1.138                Enzyme                                 
Name
mannitol 2-dehydrogenase (NADP+);
mannitol 2-dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-mannitol:NADP+ 2-oxidoreductase
Reaction(IUBMB)
D-mannitol + NADP+ = D-fructose + NADPH + H+ [RN:R00870]
Reaction(KEGG)
R00870
Substrate
D-mannitol [CPD:C00392];
NADP+ [CPD:C00006]
Product
D-fructose [CPD:C00095];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.138 created 1972
Pathway
ec00051  Fructose and mannose metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:14109183]
  Authors
EDMUNDOWICZ JM, WRISTON JC Jr.
  Title
MANNITOL DEHYDROGENASE FROM AGARICUS CAMPESTRIS.
  Journal
J Biol Chem 238:3539-41 (1963)
Reference
2  [PMID:14320506]
  Authors
STROBEL GA, KOSUGE T.
  Title
POLYOL METABOLISM IN DIPLODIA VITICOLA DESM.
  Journal
Arch Biochem Biophys 109:622-6 (1965)
DOI:10.1016/0003-9861(65)90409-1
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.138
IUBMB Enzyme Nomenclature: 1.1.1.138
ExPASy - ENZYME nomenclature database: 1.1.1.138
BRENDA, the Enzyme Database: 1.1.1.138
CAS: 37250-68-3

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Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (62)   
   UniProt (25)   
   SWISS-PROT (6)   
   RefSeq(pep) (3)   
   PDBSTR (28)   
DNA sequence (32)   
   RefSeq(nuc) (6)   
   GenBank (14)   
   EMBL (12)   
3D Structure (4)   
   PDB (4)   
Protein domain (3)   
   InterPro (3)   
All databases (112)   

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