KEGG   ENZYME: 1.1.1.152
Entry
EC 1.1.1.152                Enzyme                                 
Name
3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase;
etiocholanolone 3alpha-dehydrogenase;
etiocholanolone 3alpha-dehydrogenase;
3alpha-hydroxy-5beta-steroid dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase
Reaction(IUBMB)
3alpha-hydroxy-5beta-androstane-17-one + NAD+ = 5beta-androstane-3,17-dione + NADH + H+ [RN:R04309]
Reaction(KEGG)
R04309
Substrate
3alpha-hydroxy-5beta-androstane-17-one;
NAD+ [CPD:C00003]
Product
5beta-androstane-3,17-dione [CPD:C03772];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.1.1.152 created 1972
Pathway
ec00140  Steroid hormone biosynthesis
Reference
1  [PMID:5365796]
  Authors
Roe CR, Kaplan NO.
  Title
Purification and substrate specificities of bacterial hydroxysteroid dehydrogenases.
  Journal
Biochemistry 8:5093-103 (1969)
DOI:10.1021/bi00840a063
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.152
IUBMB Enzyme Nomenclature: 1.1.1.152
ExPASy - ENZYME nomenclature database: 1.1.1.152
BRENDA, the Enzyme Database: 1.1.1.152
CAS: 37250-77-4

  All links  
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (11)   
   UniProt (11)   
DNA sequence (4)   
   GenBank (2)   
   EMBL (2)   
All databases (24)   

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