| Entry |
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| Name |
1,2-dihydroxynaphthalene dioxygenase;
1,2-DHN dioxygenase;
DHNDO;
1,2-dihydroxynaphthalene oxygenase;
1,2-dihydroxynaphthalene:oxygen oxidoreductase
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| Class |
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
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| Sysname |
naphthalene-1,2-diol:oxygen oxidoreductase
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| Reaction(IUBMB) |
naphthalene-1,2-diol + O2 = 2-hydroxy-2H-chromene-2-carboxylate [RN: R04117]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
2-hydroxy-2H-chromene-2-carboxylate [CPD: C06204]
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| Comment |
This enzyme is involved in naphthalene degradation. Requires Fe2+.
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| History |
EC 1.13.11.56 created 2010, modified 2010
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| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K14583 | 1,2-dihydroxynaphthalene dioxygenase |
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| Genes |
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| Reference |
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| Authors |
Kuhm AE, Stolz A, Ngai KL, Knackmuss HJ |
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| Title |
Purification and characterization of a 1,2-dihydroxynaphthalene dioxygenase from a bacterium that degrades naphthalenesulfonic acids. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Keck A, Conradt D, Mahler A, Stolz A, Mattes R, Klein J |
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| Title |
Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Patel TR, Barnsley EA |
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| Title |
Naphthalene metabolism by pseudomonads: purification and properties of 1,2-dihydroxynaphthalene oxygenase. |
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| Journal |
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| Sequence |
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| Other DBs |
| UM-BBD (Biocatalysis/Biodegradation Database): | 1.13.11.56 |
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