Entry
Name
pyrrole-2-carboxylate monooxygenase;
pyrrole-2-carboxylate oxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
pyrrole-2-carboxylate,NADH:oxygen oxidoreductase (5-hydroxylating)
Reaction(IUBMB)
pyrrole-2-carboxylate + NADH + H+ + O2 = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O [RN:
R09586 ]
Reaction(KEGG)
Substrate
Product
Comment
A flavoprotein (FAD). The enzyme initiates the degradation of pyrrole-2-carboxylate.
History
EC 1.14.13.130 created 2011
Reference
Authors
Hormann K, Andreesen JR
Title
Purification and characterization of a pyrrole-2-carboxylate oxygenase from Arthrobacter strain Py1.
Journal
Biol Chem Hoppe Seyler 375:211-8 (1994)
Reference
Authors
Becker D, Schrader T, Andreesen JR
Title
Two-component flavin-dependent pyrrole-2-carboxylate monooxygenase from Rhodococcus sp.
Journal
Other DBs