Entry
Name
2-nitrophenol 2-monooxygenase;
2-nitrophenol oxygenase;
nitrophenol oxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming)
Reaction(IUBMB)
2-nitrophenol + 2 NADPH + 2 H+ + O2 = catechol + nitrite + 2 NADP+ + H2O [RN:
R00828 ]
Reaction(KEGG)
Substrate
Product
Comment
Involved in the metabolism of nitro-aromatic compounds by a strain of Pseudomonas putida.
History
EC 1.14.13.31 created 1989
Reference
Authors
Zeyer J, Kocher HP, Timmis KN.
Title
Influence of para-substituents on the oxidative metabolism of o-nitrophenols by Pseudomonas putida B2.
Journal
Other DBs
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.13.31