KEGG ENZYME: 1.4.1.11

ENZYME: 1.4.1.11

Entry

EC 1.4.1.11                 Enzyme

Name

L-erythro-3,5-diaminohexanoate dehydrogenase;
L-3,5-diaminohexanoate dehydrogenase

Class

Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor

Sysname

L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating)

Reaction(IUBMB)

L-erythro-3,5-diaminohexanoate + H2O + NAD+ = (S)-5-amino-3-oxohexanoate + NH3 + NADH + H+ [RN:R03349]

Reaction(KEGG)

R03349

Substrate

L-erythro-3,5-diaminohexanoate [CPD:C01186];
H2O [CPD:C00001];
NAD+ [CPD:C00003]

Product

(S)-5-amino-3-oxohexanoate [CPD:C03656];
NH3 [CPD:C00014];
NADH [CPD:C00004];
H+ [CPD:C00080]

History

EC 1.4.1.11 created 1976

Pathway

ec00310

Lysine degradation

ec01100

Metabolic pathways

Orthology

K18012

L-erythro-3,5-diaminohexanoate dehydrogenase

Genes

RFR:

Rfer_3890

NOK:	FAY22_04170

ARES:

IWH25_08660

APET:

ToN1_41350

AZA:	AZKH_1574(yhdH)

AZI:	AzCIB_1066

NOH:	G5V57_09660

DEK:	DSLASN_49450(kdd)

ADE:

Adeh_3294

ACP:	A2cp1_3414

AFW:	Anae109_3348

ANK:	AnaeK_3370

AORY:

AMOR_39750(kdd)

APAU:

AMPC_17840(kdd)

MXA:

MXAN_4391

MSD:	MYSTI_04880

MYM:	A176_002511

MFB:	MFUL124B02_26705

MYX:	QEG98_23545

CCX:	COCOR_03521

MFU:	LILAB_30045

MMAS:

MYMAC_004305

SUR:	STAUR_4751

AGE:	AA314_04545

AVM:	JQX13_36705

MBD:	MEBOL_007836

VIN:	AKJ08_2044

SCL:

sce2462

SCU:	SCE1572_14815

CCRO:

CMC5_039320

PAUU:

E8A73_026785

MRM:	A7982_05652

LLU:	AKJ09_02720

BSED:

DN745_01640

PCAY:

FRD00_14910

BBAE:

FRD01_13890

AFX:	JZ786_00845

ACUR:

JZ785_19345

ACYC:

JI721_05895

TUM:	CBW65_05635

TAB:	CIG75_01535

LFB:	C1X05_16420

TVU:	AB849_005115

KPUL:

GXN76_15770

KEB:	GXN75_17105

PABS:

JIR001_31260(kdd)

CLS:	CXIVA_06650

CPAT:

CLPA_c31490(kdd)

CPAE:

CPAST_c31490(kdd)

CEU:	A7L45_04290

CARG:

RSJ17_19910

CCAA:

KQH81_17165

CRW:	CROST_000180(kdd)

CFB:	CLFE_002820(kdd)

CAUN:

CLAUR_029770(kdd)

CTAG:

LL095_01360

CRS:	FQB35_13855

CPRF:

K7H06_00025

CRAS:

KVH43_03375

OCW:	OW730_07270

PROQ:

P6M73_04605

FPLA:

A4U99_02925 A4U99_11320

VFA:	MM35RIKEN_07350(kdd)

VCOP:

MM50RIKEN_12220(kdd)

STH:

STH34

DAI:	Desaci_1869

FWA:	DCMF_21025

AACX:

DEACI_2072

ACAE:

HYG86_10295

IBU:	IB211_00979

PROM:

QO263_00640

EUU:	ADJ67_02630

LUA:	D4A81_03620

LGG:	QJR73_02895

VGU:	HYG85_18530

VPY:	HZI73_18000

AMIJ:

EQM06_11660 EQM06_11665

AMIC:

Ami3637_09130 Ami3637_09135

ABUT:

Ami103574_15010 Ami103574_15015

ETM:	CE91St48_07370(kdd_1) CE91St48_07380(kdd_2)

AMT:

Amet_4553

AOE:

Clos_0417

GFE:	Gferi_11535

CSPO:

QNI18_05450

TEB:	T8CH_2403(kdd)

THYR:

P4S50_05140

CST:	CLOST_1383(kdd)

TTE:

TTE0722

TWI:	Thewi_0851

NTH:	Nther_1883 Nther_1902

HPK:	Hprae_1564

HALS:

D7D81_18040

IFN:	GM661_14605

AFT:	BBF96_12085 BBF96_13605

KME:	H0A61_00953(kdd)

SPOA:

EQM13_02785

KPAR:

JL105_00825

TIZ:	RBU61_15660

SEDZ:

JYG23_11300

PUF:

UFO1_1637

PFT:

JBW_02728

FCZ:	IMF26_07300

MANR:

MPAN_016010(kdd)

MBJ:	KQ51_00862(kdd)

XCL:	G4Z02_00825

TBK:	HF295_06575

TBM:	BK010_00740

TBZ:	BK011_00640

MPHL:

MPHLCCUG_04685(kdd)

ICA:	Intca_1790

ARS:	ADJ73_12520

TEH:	GKE56_04775

PHW:	G7075_06415

PEI:	H9L10_05995

TED:	U5C87_14715

ORN:	DV701_02925

OCP:	NF557_08930

NCA:

Noca_2662

NOY:	EXE57_02155

NOI:	FCL41_08525

NOO:	FE634_10510

NDP:	E2C04_09125

NSN:	EXE58_17605

NANO:

G5V58_11080

NMES:

H9L09_20195

NPI:	G7071_14785

NAQU:

ENKNEFLB_02386(kdd)

NRO:	K8W59_08680

NOQ:	LN652_02040

NCQ:	K6T13_09120

NPS:	KRR39_08640

KFL:

Kfla_3604

KQI:	F1D05_03980

KSL:	OG809_32765

TCU:

Tcur_2340

AGRA:

AGRA3207_000449

AMAZ:

LUW76_03390

ACIR:

OG979_38010

SPIQ:

OHA34_02715

ACTQ:

OG417_28725

BLAP:

MVA48_03865

MMAR:

MODMU_2629

SESP:

BN6_43200

SSYI:

EKG83_24045

KAL:

KALB_4421

KUT:	JJ691_26880(kdd)

KPHY:

AOZ06_28000

LED:	BBK82_41130

ALO:

CRK56462

ACTU:

Actkin_03088(kdd)

CROS:

N8J89_23670

STP:	Strop_2263

SAQ:

Sare_2382

MAU:	Micau_3120

MIL:

ML5_5275

MICB:

MicB006_2174

MTUA:

CSH63_09515

MICH:

FJK98_17905

MTEM:

GCE86_10820

MCAB:

HXZ27_19865

MSAG:

GCM10017556_54720(kdd)

VMA:	VAB18032_20370

VER:	HUT12_17870

MENO:

Jiend_59910(kdd)

MCHL:

PVK74_05870

MFEU:

H1D33_20965

MPRN:

Q3V37_21625

MHAW:

RMN56_27205

ASE:

ACPL_2805

AMS:	AMIS_47620

ACTN:

L083_3924

AFS:

AFR_21820

ACTS:

ACWT_2741

AIH:	Aiant_75440(kdd)

ACTR:

Asp14428_06220(kdd)

ACTL:

L3i22_031800(kdd)

ASIC:

Q0Z83_010230(kdd)

AOU:	ACTOB_002928

PLK:	CIK06_14130

PLAB:

C6361_03345

PLAT:

C6W10_18280

PFLA:

Pflav_024740

PSUU:

Psuf_079130(kdd)

ATL:	Athai_29200(kdd)

ASER:

Asera_45340(kdd)

PRY:	Prubr_60550(kdd)

CATI:

CS0771_51080(kdd)

DVC:	Dvina_27785

DFU:	Dfulv_24915

DROS:

Drose_19980

DAUR:

Daura_26265

DMAT:

Dmats_23110

NHY:	JQS43_13165

CCAZ:

COUCH_20855

SNA:

Snas_3952

NAV:	JQS30_07335

GLY:	K3N28_19465

VAB:	WPS_33200(kdd)

GEP:	Q9293_15635

FNU:

FN1867

FNC:	HMPREF0946_01615

FNT:	HMPREF0405_01363

FUS:	HMPREF0409_01395

FNE:	FSDG_01974

FHW:	RN87_00400

FPD:	CTM68_06730

FVA:	FV113G1_13770

FUL:	C4N20_15460

FGO:	C4N16_05140

FNF:	BSQ88_03855

FPEI:

C4N17_12365

FCI:	I6I83_03010(kdd)

FHO:	H9Q81_09950

FPOL:

ERS445057_00492

CSOM:

MKD34_03785

PGI:

PG_1069

PGN:

PGN_1165

PGT:	PGTDC60_1139

PAH:	Poras_0575

PCRE:

NCTC12858_01515

PCAG:

NCTC12856_01004

PEND:

LA319_06745

PSOE:

CE91St14_15590(kdd)

PET:	PEIBARAKI_4150

OSP:	Odosp_3172

BUY:	D8S85_10220 D8S85_10225

BVIR:

I6J59_05605 I6J59_05610

BFH:	F1611_19355 F1611_19360

BACC:

BRDCF_p1072 BRDCF_p1073

MBAS:

ALGA_2256

CACI:

CLOAM1348(kdd)

TLE:

Tlet_1664

PHY:	AJ81_05120

TME:

Tmel_0191

TAF:

THA_423

THP:	BG95_02090

THER:

Y592_02095

TFE:	JYK00_06040

FNO:

Fnod_0208

FPE:	Ferpe_0540

FIA:	NA23_03015

FRR:	IB67_05770

OCY:	OSSY52_05670(kdd)

PMO:

Pmob_1079

MPZ:	Marpi_0477

MARN:

LN42_02760

MAEO:

JRV97_01885

OCS:	OF820_10900

KOL:

Kole_0964

KPF:	IX53_04765

MPG:	Theba_2112

MINF:

MESINF_1635(kdd)

ASAC:

ATHSA_1333

LOB:	NEF87_002591

PSYT:

DSAG12_00557

» show all

Reference

1 [PMID:4344229]

Authors

Baker JJ, Jeng I, Barker HA.

Title

Purification and properties of L-erythro-3,5-diaminohexanoate dehydrogenase from a lysine-fermenting Clostridium.

Journal

J Biol Chem 247:7724-34 (1972)

Other DBs

ExplorEnz - The Enzyme Database:

1.4.1.11

IUBMB Enzyme Nomenclature:

1.4.1.11

ExPASy - ENZYME nomenclature database:

1.4.1.11

BRENDA, the Enzyme Database:

1.4.1.11

CAS:	37377-90-5

DBGET integrated database retrieval system