Oxidoreductases;
Acting on a sulfur group of donors;
With a cytochrome as acceptor
BRITE hierarchy

thiosulfate:ferricytochrome-c oxidoreductase

2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c [RN:R00029]

R00029
Reaction

thiosulfate [CPD:C00320];
ferricytochrome c [CPD:C00125]

The enzyme catalyses the reversible formation of a sulfur-sulfur bond between the sulfane atoms of two thiosulfate molecules, yielding tetrathionate and releasing two electrons. In many bacterial species the enzyme is a diheme c-type cytochrome. In a number of organisms, including Thiomonas intermedia and Sideroxydans lithotrophicus, a second diheme cytochrome (TsdB) acts as the electron acceptor. However, some organisms, such as Allochromatium vinosum, lack TsdB. The electron acceptor in these organisms may be the high-potential iron-sulfur protein (HiPIP).

EC 1.8.2.2 created 1990

1

2

3  [PMID:23421726]

4  [PMID:25673691]

5  [PMID:27694441]