| Entry |
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| Name |
glutathione---homocystine transhydrogenase
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| Class |
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor
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| Sysname |
glutathione:homocystine oxidoreductase
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| Reaction(IUBMB) |
2 glutathione + homocystine = glutathione disulfide + 2 homocysteine [RN: R01110]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
glutathione disulfide [CPD: C00127];
homocysteine [CPD: C00155]
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| Comment |
The reactions catalysed by this enzyme and by others in this subclass may be similar to those catalysed by EC 2.5.1.18 glutathione transferase.
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| History |
EC 1.8.4.1 created 1961
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| Pathway |
| ec00270 | Cysteine and methionine metabolism |
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| Reference |
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| Authors |
RACKER E. |
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| Title |
Glutathione-homocystine transhydrogenase. |
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| Journal |
J Biol Chem 217:867-74 (1955) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.8.4.1 |
| ExPASy - ENZYME nomenclature database: | 1.8.4.1 |
| BRENDA, the Enzyme Database: | 1.8.4.1 |
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