Entry |
|
Name |
10-hydroxydihydrosanguinarine 10-O-methyltransferase
|
Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
|
Sysname |
S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase
|
Reaction(IUBMB) |
S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine = S-adenosyl-L-homocysteine + dihydrochelirubine [RN: R04707]
|
Reaction(KEGG) |
|
Substrate |
S-adenosyl-L-methionine [CPD: C00019];
10-hydroxydihydrosanguinarine [CPD: C05247]
|
Product |
S-adenosyl-L-homocysteine [CPD: C00021];
dihydrochelirubine [CPD: C05194]
|
Comment |
This reaction is part of the pathway for synthesis of benzophenanthridine alkaloids in plants.
|
History |
EC 2.1.1.119 created 1999
|
Pathway |
ec00950 | Isoquinoline alkaloid biosynthesis |
ec01110 | Biosynthesis of secondary metabolites |
|
Reference |
1 |
Authors |
De-Eknamkul, W., Tanahashi, T. and Zenk, M.H. |
Title |
Enzymic 10-hydroxylation and 10-O-methylation of dihydrosanguinarine in dihydrochelirubine formation by Eschscholtzia. |
Journal |
Phytochemistry 31:2713-2717 (1992) |
Other DBs |
ExPASy - ENZYME nomenclature database: | 2.1.1.119 |
|