Entry |
|
Name |
flavonoid 4'-O-methyltransferase;
SOMT-2;
4'-hydroxyisoflavone methyltransferase
|
Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
|
Sysname |
S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase
|
Reaction(IUBMB) |
S-adenosyl-L-methionine + a 4'-hydroxyflavanone = S-adenosyl-L-homocysteine + a 4'-methoxyflavanone [RN: R09792]
|
Reaction(KEGG) |
|
Substrate |
S-adenosyl-L-methionine [CPD: C00019];
4'-hydroxyflavanone [CPD: C19896]
|
Product |
S-adenosyl-L-homocysteine [CPD: C00021];
4'-methoxyflavanone [CPD: C19895]
|
Comment |
The enzyme catalyses the 4'-methylation of naringenin. In vitro it catalyses the 4'-methylation of apigenin, quercetin, daidzein and genistein.
|
History |
EC 2.1.1.231 created 2011
|
Pathway |
ec01110 | Biosynthesis of secondary metabolites |
|
Orthology |
K23053 | flavonoid 4'-O-methyltransferase |
|
Genes |
|
Reference |
|
Authors |
Kim DH, Kim BG, Lee Y, Ryu JY, Lim Y, Hur HG, Ahn JH |
Title |
Regiospecific methylation of naringenin to ponciretin by soybean O-methyltransferase expressed in Escherichia coli. |
Journal |
|
Sequence |
|
Other DBs |
ExPASy - ENZYME nomenclature database: | 2.1.1.231 |
|