KEGG   ENZYME: 2.1.1.253
Entry
EC 2.1.1.253                Enzyme                                 
Name
[methyl-Co(III) tetramethylammonium-specific corrinoid protein]---coenzyme M methyltransferase;
methyltransferase 2 (ambiguous);
mtqA (gene name)
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
methylated tetramethylammonium-specific corrinoid protein:CoM methyltransferase
Reaction(IUBMB)
a [methyl-Co(III) tetramethylammonium-specific corrinoid protein] + CoM = methyl-CoM + a [Co(I) tetramethylammonium-specific corrinoid protein] [RN:R10000]
Reaction(KEGG)
R10000
Substrate
[methyl-Co(III) tetramethylammonium-specific corrinoid protein];
CoM [CPD:C03576]
Product
methyl-CoM [CPD:C03920];
[Co(I) tetramethylammonium-specific corrinoid protein]
Comment
The enzyme, which is involved in methanogenesis from tetramethylammonium, catalyses the transfer of a methyl group from a corrinoid protein (see EC 2.1.1.252, tetramethylammonium---corrinoid protein Co-methyltransferase), where it is bound to the cobalt cofactor, to CoM, forming the substrate for EC 2.8.4.1, coenzyme-B sulfoethylthiotransferase, the enzyme that catalyses the final step in methanogenesis.
History
EC 2.1.1.253 created 2012
Reference
1  [PMID:9732435]
  Authors
Asakawa S, Sauer K, Liesack W, Thauer RK
  Title
Tetramethylammonium:coenzyme M methyltransferase system from methanococcoides sp
  Journal
Arch Microbiol 170:220-6 (1998)
DOI:10.1007/s002030050636
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.253
IUBMB Enzyme Nomenclature: 2.1.1.253
ExPASy - ENZYME nomenclature database: 2.1.1.253
BRENDA, the Enzyme Database: 2.1.1.253

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
All databases (7)   

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