Entry
Name
[fructose-bisphosphate aldolase]-lysine N-methyltransferase;
rubisco methyltransferase;
ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase;
ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase;
S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:[fructose-bisphosphate aldolase]-lysine N6-methyltransferase
Reaction(IUBMB)
3 S-adenosyl-L-methionine + [fructose-bisphosphate aldolase]-L-lysine = 3 S-adenosyl-L-homocysteine + [fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
Substrate
S-adenosyl-L-methionine [CPD:
C00019 ];
[fructose-bisphosphate aldolase]-L-lysine [CPD:
C21364 ]
Product
S-adenosyl-L-homocysteine [CPD:
C00021 ];
[fructose-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine [CPD:
C21365 ]
Comment
The enzyme methylates a conserved lysine in the C-terminal part of higher plant fructose-bisphosphate aldolase (EC
4.1.2.13 ). The enzyme from pea (Pisum sativum) also methylates Lys-14 in the large subunits of hexadecameric higher plant ribulose-bisphosphate-carboxylase (EC
4.1.1.39 ) [2], but that from Arabidopsis thaliana does not.
History
EC 2.1.1.259 created 2012
Orthology
K00592 [ribulose-bisphosphate carboxylase]/[fructose-bisphosphate aldolase]-lysine N-methyltransferase
Genes
CSAT : 104740061 104755697 104772851
HSYR : 120169338 120210702
EGR : 104422322 104434604 104453926 104453927 120293321
PVU : PHAVU_002G169400g PHAVU_005G037700g
LJA : Lj4g3v0684250.2(Lj4g3v0684250.2)
LANG : 109339197 109349547
CMAX : 111471356 111471861
CMOS : 111450646 111454704
CPEP : 111799237 111805617 111805618
SPEN : 107020229 107020231
SSTN : 125866777 125867676
CANN : 107847854 107848269
NTA : 107778201(RBCMT) 107809813
CSIN : 114264208 114306448
ATRI : 130809122 130820119
PSOM : 113299904 113300303
DOSA : Os09t0411650-01(Os09g0411650)
TAES : 123103906 123114815 123121680
SMO : SELMODRAFT_119151 SELMODRAFT_449995
VCN : VOLCADRAFT_109735(VRMT1)
MPP : MICPUCDRAFT_36635(JGI:MicpuC2_36635)
» show all
Taxonomy
Reference
Authors
Magnani R, Nayak NR, Mazarei M, Dirk LM, Houtz RL
Title
Polypeptide substrate specificity of PsLSMT. A set domain protein methyltransferase.
Journal
Reference
Authors
Mininno M, Brugiere S, Pautre V, Gilgen A, Ma S, Ferro M, Tardif M, Alban C, Ravanel S
Title
Characterization of chloroplastic fructose 1,6-bisphosphate aldolases as lysine-methylated proteins in plants.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.1.1.259