KEGG   ENZYME: 2.3.1.100
Entry
EC 2.3.1.100                Enzyme                                 
Name
[myelin-proteolipid] O-palmitoyltransferase;
myelin PLP acyltransferase;
acyl-protein synthetase;
myelin-proteolipid O-palmitoyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase
Reaction(IUBMB)
palmitoyl-CoA + [myelin proteolipid] = CoA + O-palmitoyl-[myelin proteolipid] [RN:R04022]
Reaction(KEGG)
R04022
Substrate
palmitoyl-CoA [CPD:C00154];
myelin proteolipid [CPD:C02706]
Product
CoA [CPD:C00010];
O-palmitoyl-[myelin proteolipid] [CPD:C04386]
Comment
The enzyme in brain transfers long-chain acyl residues to the endogenous myelin proteolipid
History
EC 2.3.1.100 created 1989
Reference
1  [PMID:3818589]
  Authors
Bizzozero OA, McGarry JF, Lees MB.
  Title
Acylation of endogenous myelin proteolipid protein with different acyl-CoAs.
  Journal
J Biol Chem 262:2138-45 (1987)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.100
IUBMB Enzyme Nomenclature: 2.3.1.100
ExPASy - ENZYME nomenclature database: 2.3.1.100
BRENDA, the Enzyme Database: 2.3.1.100
CAS: 82657-98-5

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