Entry Name rosmarinate synthase;
Class Transferases;BRITE hierarchy
Sysname caffeoyl-CoA:(R)-3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyl-transferase
Reaction(IUBMB) caffeoyl-CoA + (R)-3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate [RN:
R03374 ]
Reaction(KEGG) Substrate caffeoyl-CoA [CPD:
C00323 ];
(R)-3-(3,4-dihydroxyphenyl)lactate [CPD:
C22038 ]
Product Comment Involved, with EC
1.1.1.237 (hydroxyphenylpyruvate reductase) in the biosynthesis of rosmarinic acid. Characterized from the plant Melissa officinalis L. (lemon balm).
History EC 2.3.1.140 created 1992, modified 2013
Pathway Orthology Genes SSPL : 121747317 121753299
Taxonomy Reference 1
Authors Petersen, M. and Alfermann, A.W.
Title Two new enzymes of rosmarinic acid biosynthesis from cell cultures of Coleus blumei: hydroxyphenylpyruvate reductase and rosmarinic acid synthase.
Journal Z Naturforsch C: Biosci 43:501-504 (1988)
Reference 2
Authors Petersen, M. S.
Title Characterization of rosmarinic acid synthase from cell cultures of Coleus blumei.
Journal Phytochemistry 30:2877-2881 (1991)
Reference Authors Weitzel C, Petersen M
Title Cloning and characterisation of rosmarinic acid synthase from Melissa officinalis L.
Journal Sequence Other DBs ExPASy - ENZYME nomenclature database: 2.3.1.140
