KEGG   ENZYME: 2.3.1.158
Entry
EC 2.3.1.158                Enzyme                                 
Name
phospholipid:diacylglycerol acyltransferase;
PDAT
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase
Reaction(IUBMB)
phospholipid + 1,2-diacyl-sn-glycerol = lysophospholipid + triacylglycerol [RN:R05333]
Reaction(KEGG)
R05333
Substrate
phospholipid [CPD:C00865];
1,2-diacyl-sn-glycerol [CPD:C00641]
Product
lysophospholipid [CPD:C06254];
triacylglycerol [CPD:C00422]
Comment
This enzyme differs from EC 2.3.1.20, diacylglycerol O-acyltransferase, by synthesising triacylglycerol using an acyl-CoA-independent mechanism. The specificity of the enzyme for the acyl group in the phospholipid varies with species, e.g., the enzyme from castor bean (Ricinus communis) preferentially incorporates vernoloyl (12,13-epoxyoctadec-9-enoyl) groups into triacylglycerol, whereas that from the hawk's beard (Crepis palaestina) incorporates both ricinoleoyl (12-hydroxyoctadec-9-enoyl) and vernoloyl groups. The enzyme from the yeast Saccharomyces cerevisiae specifically transfers acyl groups from the sn-2 position of the phospholipid to diacylglycerol, thus forming an sn-1-lysophospholipid.
History
EC 2.3.1.158 created 2001
Pathway
ec00561  Glycerolipid metabolism
ec01100  Metabolic pathways
Orthology
K00679  phospholipid:diacylglycerol acyltransferase
Genes
ATH: AT3G44830 AT5G13640(PDAT)
ALY: 9309690 9313438
CRB: 17881928 17885438
CSAT: 104705618 104735371 104769582 104780334 104790735
EUS: EUTSA_v10002852mg EUTSA_v10012888mg
BRP: 103846553 103850885
BNA: 106372279 106377188 106406534 125579045
BOE: 106318490 106327439
RSZ: 108817295 108842067
THJ: 104799356 104809891 104814810
CPAP: 110808547 110817685 110818323
CIT: 102608065 102609133 102609799
CIC: CICLE_v10025070mg CICLE_v10025078mg CICLE_v10027727mg
PVY: 116120024 116142184 116146808
MINC: 123199205 123200792 123211318 123219550
TCC: 18588322 18590424 18596196
GRA: 105772831 105774265 105784202 105792333 105792937 105799046
GHI: 107891726 107897707 107901080 107932867 107941265 107944192 107947285 107949699 107953304 107954163 107960298 121204773
GAB: 108456991 108458391 108470153 108474009 108480395 108485128
HSYR: 120115067 120116364 120129627 120134614 120149808 120151224 120152562 120159321 120217305
DZI: 111274675 111279003 111286760 111299177 111303069 111303764
EGR: 104421248 104422999 104436439
GMX: 100779225 100800857 100803760 100806313 100812643
GSJ: 114372974 114379317 114382442 114390510 114392747 114418155
PVU: PHAVU_003G133000g PHAVU_010G132900g PHAVU_011G088800g
VRA: 106769440 106774144
VAR: 108319333 108338425
VUN: 114166844 114178533
VUM: 124823546 124846718 124846736
CCAJ: 109799093 109802310 109808306
APRC: 113846357 113849576 113860043
MTR: 25492334 25500534
TPRA: 123881556 123884317
CAM: 101497807 101499408 101505056
PSAT: 127076307 127105648
VVO: 131616401 131637879
LJA: Lj3g3v2656650.1(Lj3g3v2656650.1) Lj4g3v2179270.1(Lj4g3v2179270.1)
ADU: 107457657 107464761 107479082
AIP: 107618017 107634440 107643486
AHF: 112710451 112723677 112735910 112770407 112775717
LANG: 109334037 109347629 109355287 109356249
PCIN: 129288935 129309969 129315649 129321050
QSA: O6P43_022460 O6P43_027577 O6P43_028465
FVE: 101301468 101311410
RCN: 112163750 112187750
PPER: 18771381 18774807
PMUM: 103326545 103340552
PAVI: 110749222 110755303
PDUL: 117631934 117634845
MDM: 103400853 103448013 103450792
MSYL: 126591442 126604143 126606472
PXB: 103929853 103932552 103951912
ZJU: 107403549 107410573 107424140
MNT: 21396621 21397235 21409968
CSAV: 115698889 115705212 115707043
CSV: 101215610 101222563
CMO: 103497986 103500706
BHJ: 120085798 120088742
MCHA: 111011365 111018295
CMAX: 111484072 111488585 111494451
CMOS: 111448684 111456080 111464287
CPEP: 111777293 111778524 111807354
RCU: 8266990 8272509 8284674
JCU: 105631411 105637340 105637933(PDAT)
HBR: 110632849 110635770 110641537 110651489 110668138
MESC: 110612221 110613312 110613532 110626552 110626764
POP: 18098005 7475706 7490955
PEU: 105111967 105118354 105133404 105136421
PALZ: 118034818 118038074 118045532 118060023
JRE: 108985608 109000668 109005305 109008819
CILL: 122292297 122300922 122304312 122307891
CAVE: 132163820 132165699 132187250
QSU: 112012906 112023522
QLO: 115976039 115976040 115989696
TWL: 119993493 120002366 120002391
VVI: 100243077 100256634 100259274
VRI: 117915678 117922549 117925314
SLY: 101258674 101259322 101261928 101263223 101266485
SPEN: 107004164 107014474 107021662 107022891 107024408
SOT: 102586946 102590232 102597079 102597924 102606040
SSTN: 125844671 125857978 125872487 125875158 125876187
SDUL: 129893309 129894181 129900758 129900946 129904573
CANN: 107848184 107861698 107874787 107875629 107877860
LBB: 132600511 132604477 132616596 132618405 132633501
NTA: 107768032 107775478 107782802 107789323 107809139 107811062 107815607 107818243
NSY: 104220307 104221715 104236791 104239807 104240673
NTO: 104090483 104097532 104116567 104121161
NAU: 109211607 109214649 109217286 109218871 109242616
INI: 109186432 109187504 109193143
ITR: 116009903 116013955 116014715
SIND: 105157789 105163255 105169966 105173654
OEU: 111401505 111401783
EGT: 105951305 105958532 105971047 105975942
SSPL: 121744432 121745022 121767668 121790702 121794181 121797749 121811371 121811380
SMIL: 130987153 130990776 131013127 131020277
SHIS: 125186420 125205938 125208495 125210556
APAN: 127239341 127243274 127251857 127262807
HAN: 110886458 110893689 110904203 110909071 118490100
ECAD: 122595117 122595250 122603264 122607890
LSV: 111892640 111899140 111901442 111905326 111910335
CCAV: 112500771 112511716 112516913 112516986 112522263
DCR: 108192584 108206149 108213502 108223304 108227780
CSIN: 114270756 114276665 114291097 114296637
RVL: 131310725 131313469 131320048
AEW: 130770873 130782761 130784598
BVG: 104883605 104899770
SOE: 110793733 110803768
CQI: 110683011 110684360 110688112 110715985
ATRI: 130813735 130824408
MOF: 131149791 131158209 131164485
NNU: 104600613 104609357 104612529
MING: 122064870 122086945
TSS: 122656175 122667478
PSOM: 113314070 113321076 113347605 113350354 113351133 113352849
OSA: 4347190
DOSA: Os09t0444200-01(Os09g0444200)
OBR: 102703714
OGL: 127784638
BDI: 100835274
ATS: 109745768
TDC: 119301544 119309383
TAES: 123103717 123111938 123121495
TUA: 125509275
LPER: 127301758
LRD: 124658202
SBI: 8081010
ZMA: 100191489 100273525
SITA: 101769545
SVS: 117843960
PVIR: 120660811 120680373
PHAI: 112880526
PDA: 103708654
EGU: 105041806
MUS: 103977610 103998045
ZOF: 122026964 122029496 122032825 122033498
DCT: 110096119
PEQ: 110022551
AOF: 109823033 109844472
MSIN: 131235112 131251683
NCOL: 116262343
ATR: 18439382 18441499
SMO: SELMODRAFT_164869 SELMODRAFT_171888
PPP: 112275614
CRE: CHLRE_02g106400v5
VCN: VOLCADRAFT_97885
MNG: MNEG_3131
CSL: COCSUDRAFT_37169
OLU: OSTLU_1469
OTA: OT_ostta09g03210
BPG: Bathy10g01290
MIS: MICPUN_58725
MPP: MICPUCDRAFT_58904(JGI:MicpuC2_58904)
SCE: YNR008W(LRO1)
SEUB: DI49_4743
SPAO: SPAR_N03100
AGO: AGOS_AFL179C
ERC: Ecym_2120
KLA: KLLA0_F06380g
KMX: KLMA_60455(LRO1)
LTH: KLTH0A05742g
ZRO: ZYRO0C05478g
CGR: CAGL0I05786g
NCS: NCAS_0G00980(NCAS0G00980)
NDI: NDAI_0F01110(NDAI0F01110)
TPF: TPHA_0D03660(TPHA0D03660)
TBL: TBLA_0A02430(TBLA0A02430)
TGB: HG536_0A08690
TDL: TDEL_0A07120(TDEL0A07120)
KAF: KAFR_0F00910(KAFR0F00910)
KNG: KNAG_0D00600(KNAG0D00600)
ZMK: HG535_0A06970
PPA: PAS_chr2-1_0878
DHA: DEHA2D09922g
PIC: PICST_72946(LRO1)
PGU: PGUG_04692
SPAA: SPAPADRAFT_132946
LEL: PVL30_001349(LRO1)
CAL: CAALFM_C100870WA(LRO1)
CTP: CTRG_04390
COT: CORT_0B11180
CDU: CD36_00820
CTEN: CANTEDRAFT_92085
YLI: YALI0E16797g
CLU: CLUG_00975
CLUS: A9F13_09g00253
CAUR: CJI96_0003728
SLB: AWJ20_3581(LRO1)
PKZ: C5L36_0A12660
BNN: FOA43_000117
BBRX: BRETT_000982
OPA: HPODL_01811
SLUD: SCDLUD_001195
NCR: NCU02416
NTE: NEUTE1DRAFT85933(NEUTE1DRAFT_85933)
SMP: SMAC_08306
PAN: PODANSg9241
PBEL: QC761_505600(LRO1)
PPSD: QC762_505600(LRO1)
PPSP: QC763_505600(LRO1)
PPSA: QC764_505600(LRO1)
TTT: THITE_2116760
MTM: MYCTH_2309146
CTHR: CTHT_0048370
MGR: MGG_03560
PPEI: PpBr36_06697
PGRI: PgNI_00461
TMN: UCRPA7_1931
SSCK: SPSK_00461
FGR: FGSG_06375
FPU: FPSE_12276
FPOA: FPOAC1_009372
FVN: FVRRES_10008
FVR: FVEG_05051
FOX: FOXG_08128
NHE: NECHADRAFT_59755
FFC: NCS54_00514400
FKR: NCS57_00552500
FMU: J7337_007087
TRE: TRIREDRAFT_121546
TRR: M419DRAFT_98582
MAW: MAC_04716
MAJ: MAA_04510
PCHM: VFPPC_17845
CMT: CCM_01242
AMUS: LMH87_005827
PLJ: VFPFJ_02264
PTKZ: JDV02_003712(LRO1)
VAL: VDBG_09717
VDA: VDAG_09453
CFJ: CFIO01_08076
CLUP: CLUP02_06211
CHIG: CH63R_01158
SAPO: SAPIO_CDS4514
ELA: UCREL1_3852
PFY: PFICI_03524
SSL: SS1G_11136
BFU: BCIN_02g05210(Bclro1)
MBE: MBM_06753
PSCO: LY89DRAFT_686481
GLZ: GLAREA_10021
ANI: ANIA_04992
AFM: AFUA_3G09950
ACT: ACLA_037790
NFI: NFIA_067340
AOR: AO090003000514
ANG: An16g03640
AFV: AFLA_001177
ALUC: AKAW2_70312S
ACHE: ACHE_20944S
APUU: APUU_30836S
PCS: N7525_001059
PDP: PDIP_76480
POU: POX_b03253
TMF: EYB26_001046
TRG: TRUGW13939_03288
CIM: CIMG_03952
CPW: CPC735_004070
URE: UREG_01995
PBL: PAAG_07904
PBN: PADG_08171
ABE: ARB_01216
TVE: TRV_01292
AJE: HCAG_05471
BGH: BDBG_02489
PNO: SNOG_03081
PTE: PTT_20057
BZE: COCCADRAFT_33431
BSC: COCSADRAFT_158418
BOR: COCMIDRAFT_83639
AALT: CC77DRAFT_947980
ARAB: EKO05_0000339
ZTR: MYCGRDRAFT_73528
PFJ: MYCFIDRAFT_155012
FFU: CLAFUR5_09068
CBET: CB0940_10472
BCOM: BAUCODRAFT_109446
NPA: UCRNP2_3325
TML: GSTUM_00000255001
SPO: SPBC776.14(plh1)
SOM: SOMG_01018(plh1)
CNE: CNL04710
CNB: CNBI2140
CNG: CNAG_05152
CGI: CGB_D2350W
CDEU: CNBG_4542
TMS: TREMEDRAFT_68093
TASA: A1Q1_06453
CCAC: CcaHIS019_0701660(LRO1)
TVS: TRAVEDRAFT_56169
DSQ: DICSQDRAFT_132754
PCO: PHACADRAFT_197922
SHS: STEHIDRAFT_60411
HIR: HETIRDRAFT_57041
PSQ: PUNSTDRAFT_105867
ADL: AURDEDRAFT_113617
FME: FOMMEDRAFT_16796
GTR: GLOTRDRAFT_135908
RSX: RhiXN_07200
LBC: LACBIDRAFT_156742(PDAT)
CCI: CC1G_02002
ABP: AGABI1DRAFT71227(AGABI1DRAFT_71227)
ABV: AGABI2DRAFT204119(AGABI2DRAFT_204119)
PCUB: JR316_0002060
MRR: Moror_1504
SCM: SCHCO_02631503(SCHCODRAFT_02631503)
CPUT: CONPUDRAFT_57356
SLA: SERLADRAFT_447691
WSE: WALSEDRAFT_59615
WIC: J056_003834
UMA: UMAG_00322
PFP: PFL1_03662
SGRA: EX895_000548
MGL: MGL_3157
MRT: MRET_2127
MSYM: MSY001_2834
PGR: PGTG_14693
PTRC: PtA15_4A107
PSTR: Pst134EA_011137
MLR: MELLADRAFT_88797
EHI: EHI_099180(57.t00020)
ACAN: ACA1_074840 ACA1_327920 ACA1_399790
PTI: PHATRDRAFT_8860
FCY: FRACYDRAFT_166543
TPS: THAPSDRAFT_261132(PDT1)
AAF: AURANDRAFT_1287 AURANDRAFT_23177
PIF: PITG_11965
PSOJ: PHYSODRAFT_355873
GTT: GUITHDRAFT_159571
TBR: Tb11.01.4790
TBG: TbgDal_XI14750
TCR: 506757.10 510359.340
LMA: LMJF_09_1040
LIF: LINJ_09_1100
LDO: LDBPK_091100
LMI: LMXM_09_1040
LBZ: LBRM_09_1100
LPAN: LPMP_091050
 » show all
Reference
1  [PMID:10829075]
  Authors
Dahlqvist A, Stahl U, Lenman M, Banas A, Lee M, Sandager L, Ronne H, Stymne S
  Title
Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants.
  Journal
Proc Natl Acad Sci U S A 97:6487-92 (2000)
DOI:10.1073/pnas.120067297
  Sequence
[sce:YNR008W]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.158
IUBMB Enzyme Nomenclature: 2.3.1.158
ExPASy - ENZYME nomenclature database: 2.3.1.158
BRENDA, the Enzyme Database: 2.3.1.158
CAS: 288587-47-3

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Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (1889)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (643)   
   KEGG MGENES (317)   
   RefGene (928)   
Protein sequence (284)   
   UniProt (236)   
   SWISS-PROT (4)   
   RefSeq(pep) (44)   
DNA sequence (176)   
   RefSeq(nuc) (77)   
   GenBank (57)   
   EMBL (42)   
Protein domain (2)   
   InterPro (2)   
All databases (2362)   

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