KEGG ENZYME: 2.3.1.73

ENZYME: 2.3.1.73

Entry

EC 2.3.1.73                 Enzyme

Name

diacylglycerol---sterol O-acyltransferase;
1,2-diacyl-sn-glycerol:sterol acyl transferase

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

1,2-diacyl-sn-glycerol:sterol O-acyltransferase

Reaction(IUBMB)

a 1,2-diacyl-sn-glycerol + sterol = a 1-acyl-sn-glycerol + sterol ester [RN:R02693]

Reaction(KEGG)

R02693 > R02692

Substrate

1,2-diacyl-sn-glycerol [CPD:C00641];
sterol [CPD:C00370]

Product

1-acyl-sn-glycerol;
sterol ester [CPD:C01958]

Comment

Cholesterol, sitosterol, campesterol and diacylglycerol can act as acceptors. Transfers a number of long-chain fatty acyl groups.

History

EC 2.3.1.73 created 1984

Pathway

ec00100

Steroid biosynthesis

Reference

Authors

Bartlett, K., Keat, M.J. and Mercer, E.I.

Title

Biosynthesis of sterol esters in Phycomyces blakesleeanus.

Journal

Phytochemistry 13:1107-1113 (1974)

Reference

2 [PMID:742884]

Authors

Garcia RE, Mudd JB.

Title

Metabolism of monoacylglycerol and diacylglycerol by enzyme preparations from spinach leaves.

Journal

Arch Biochem Biophys 191:487-93 (1978)
DOI:10.1016/0003-9861(78)90387-9

Reference

Authors

Garcia, R.E. and Mudd, J.B.

Title

1,2-Diacyl-sn-glycerol:sterol acyl transferase from spinach leaves (Spinacia oleracea L.).

Journal

Methods Enzymol 71:768-772 (1981)

Other DBs

ExplorEnz - The Enzyme Database:

2.3.1.73

IUBMB Enzyme Nomenclature:

2.3.1.73

ExPASy - ENZYME nomenclature database:

2.3.1.73

BRENDA, the Enzyme Database:

2.3.1.73

CAS:	79586-23-5

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG REACTION (2)   
   KEGG RCLASS (2)   
All databases (12)   

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