KEGG ENZYME: 2.4.1.13

ENZYME: 2.4.1.13

Entry

EC 2.4.1.13                 Enzyme

Name

sucrose synthase;
UDPglucose-fructose glucosyltransferase;
sucrose synthetase;
sucrose-UDP glucosyltransferase;
sucrose-uridine diphosphate glucosyltransferase;
uridine diphosphoglucose-fructose glucosyltransferase;
NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase

Class

Transferases;
Glycosyltransferases;
Hexosyltransferases

Sysname

NDP-alpha-D-glucose:D-fructose 2-alpha-D-glucosyltransferase (configuration-retaining)

Reaction(IUBMB)

NDP-alpha-D-glucose + D-fructose = NDP + sucrose [RN:R07256]

Reaction(KEGG)

R07256 > R00806 R06036(G) R08676

Substrate

NDP-alpha-D-glucose [CPD:C15541];
D-fructose [CPD:C00095]

Product

NDP [CPD:C00454];
sucrose [CPD:C00089]

Comment

Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose [3-9]. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis) [10].

History

EC 2.4.1.13 created 1961, modified 2003

Pathway

ec00500

Starch and sucrose metabolism

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K00695

sucrose synthase

Genes

AJM:

119037065

ATH:	AT1G73370(SUS6) AT3G43190(SUS4) AT4G02280(SUS3) AT5G20830(SUS1) AT5G37180(SUS5) AT5G49190(SUS2)

ALY:	9301791 9304569 9308917 9310083 9311669 9324989

CRB:	17877054 17877643 17881746 17882355 17887544 17895033

CSAT:

104702036 104706429 104707872 104712951 104713942 104719340 104723601 104724082 104725413 104732612 104736154 104737553 104751189 104763273 104770460

EUS:	EUTSA_v10003667mg EUTSA_v10012719mg EUTSA_v10018094mg EUTSA_v10027639mg EUTSA_v10028435mg

BRP:	103830752 103831821 103836763 103845641 103856465 103868315 103875021

BNA:	106345241 106348876 106354279 106365510 106371709 106386990 106391382 106402327 106406752 106407384 106434916 106451551 111210221 111211726 125595989 125603413

BOE:	106296231 106296386 106296521 106304017 106318311 106319066 106336052

RSZ:	108814119 108814255 108817509 108823863 108828189 108847491 108852315 130503214 130504406

THJ:	104799606 104805659 104810983 104812185 104825963 104827331

CPAP:

110807262 110812012 110815045 110825587

CIT:	102615040 102615807 102616003 102626007 102627856 102629055

CIC:	CICLE_v10004341mg CICLE_v10007483mg CICLE_v10010343mg CICLE_v10011062mg CICLE_v10018889mg

PVY:	116106406 116120517 116121153 116135571 116142065 116146707

MINC:

123194710 123200616 123204669 123206792 123216592 123219960 123226044

TCC:	18588220 18588224 18601247 18603545 18604515 18613599

GRA:	105767999 105773086 105774032 105782817 105788781 105791444 105797719 105802152

GHI:	107893375 107899372 107901027 107901030 107907080 107910106 107924200 107926875 107929861 107937480 107942366 107953943 107958826 107962183 121212571

GAB:	108463993 108466049 108466051 108468821 108469697 108479546 108481007 108489178

HSYR:

120113930 120132153 120135999 120153557 120154030 120157047 120161678 120164684 120166598 120181470 120182243 120183607 120199634

DZI:	111285632 111286797 111289721 111299212 111303031 111305045 111314106 111314681

EGR:	104422202 104425866 104426782 104436385 104437963 104437966 104440058 104440059 104440060 104449054 104456736

GMX:	100783965 100788584 100788717 100792097 100793371 100802045 100805344 100806761 100808482 100809674 100819730 547508(SS)

GSJ:	114367734 114380841 114381373 114383518 114386366 114387590 114390127 114394232 114397685 114398239 114407393 114425696

PVU:	PHAVU_001G209600g PHAVU_003G127500g PHAVU_004G142800g PHAVU_006G087300g PHAVU_008G241300g PHAVU_009G223800g PHAVU_009G250800g

VRA:	106757631 106762013 106762931 106768289 106774050 106775028

VAR:	108328968 108331593 108336175 108341918 108343245 108343673

VUN:	114162257 114162957 114178360 114180338 114185026 114186592 114193263

VUM:	124821239 124828545 124830145 124834271 124842285 124842733 124842736

CCAJ:

109800571 109803338 109807766 109809843 109812209 109814177 109819188

APRC:

113846477 113848337 113849368 113852999 113853320 113863028 113866733

MTR:	11414896 11419005 11433144 11446733 25486575 25499615

TPRA:

123882187 123891152 123907155 123910155 123916258 123920206 123920691

CAM:	101490898 101491581 101494314 101509229 101511421 101514095 101514674

PSAT:

127084279 127091212 127118331 127132648 127133097 127136197 127138723

VVO:	131594970 131610820 131620908 131622082 131628295 131630023 131638133 131638405 131639843 131642242 131643942 131662093

LJA:	Lj0g3v0242009.1(Lj0g3v0242009.1) Lj1g3v4875640.1(Lj1g3v4875640.1) Lj1g3v4875640.2(Lj1g3v4875640.2) Lj2g3v2507780.1(Lj2g3v2507780.1) Lj3g3v1238910.1(Lj3g3v1238910.1) Lj4g3v2215210.1(Lj4g3v2215210.1) Lj6g3v1162830.1(Lj6g3v1162830.1) Lj6g3v1162830.2(Lj6g3v1162830.2) Lj6g3v1468270.2(Lj6g3v1468270.2)

ADU:	107479418 107481015 107490724 107492465 107496082

AIP:	107630591 107631415 107638421 107644054 107645662

AHF:	112695778 112696276 112733763 112738386 112740751 112750827 112756421 112790604 112791679 112802440

LANG:

109326830 109327632 109327633 109330009 109335230 109347960 109356508 109357071 109358788 109362433

PCIN:

129296330 129303231 129305712 129308377 129314448 129317877

QSA:	O6P43_002617 O6P43_005274 O6P43_007201 O6P43_010804 O6P43_010806 O6P43_014227 O6P43_020529 O6P43_021780 O6P43_022532 O6P43_034209

FVE:	101292831 101298794 101299138 101306372 101309357 101313949

RCN:	112169184 112176664 112186368 112188591 112194953 112198236

PPER:

18767223 18770262 18777229 18781998 18790747 18791635

PMUM:

103323061 103327363 103333990 103338879 103340632 103343570

PAVI:

110745885 110748673 110749140 110749336 110750201 110750203 110765091

PDUL:

117616724 117616772 117620602 117624116 117625045 117628670 117636070 117636939

MDM:	103400901 103409880 103414597 103414598 103426254 103444250 103449164(SS) 103453958 103455689

MSYL:

126591295 126596199 126598550 126603861 126606390 126608024 126608040 126612519 126625034 126634136

PXB:	103933877 103935319 103935320 103939687 103940505 103940506 103943695 103946870 103948072 103950289 103956794 103956799 103959924 103959925 103967199

ZJU:	107406759 107416188 107419708 107426335 107433125

MNT:	21386815 21391172 21394396 21402491 21407811

CSAV:

115705430 115705483 115714498 115721870 115722614

CSV:	101203847 101211461 101213767 101216865

CMO:	103483781 103492399 103494755 103501373

BHJ:	120067696 120070539 120084220 120091208

MCHA:

111008572 111011768 111016476 111022442

CMAX:

111466367 111484831 111487031 111489205 111492795 111493280 111495515

CMOS:

111431589 111438640 111444757 111452459 111452903 111461509 111462013

CPEP:

111779778 111782779 111787525 111788999 111793310 111803958 111809443

RCU:	8259046 8259900 8275091 8278014 8278767

JCU:	105636138 105636179 105636921 105642561 105643468

HBR:	110636873 110637152 110637531 110638834 110644580 110653739 110659273

MESC:

110602887 110603638 110610584 110611700 110612799 110617712 110630948

POP:	18100284 18105619 7454032 7461280 7478850 7487419 7490531

PEU:	105110371 105112458 105115703 105135236 105136321 105139213 105142024

PALZ:

118030349 118031772 118044357 118046817 118048507 118056701 118057271

JRE:	108981886 108988247 108990945 108993242 108994129 108994212

CILL:

122296245 122299226 122302940 122304228 122306732 122307734 122314839

CAVE:

132164910 132172810 132181029 132183910

QSU:	111984605 111984866 111993270 112018943 112019923 112020114 112028228

QLO:	115962644 115968544 115969012 115969119 115970897 115976201 115995023

TWL:	119982744 119986680 119996757 120004142 120005735 120012929

VVI:	100243135 100249279 100252799 100266759 100267606

VRI:	117912209 117914836 117917576 117924712 117934381

SLY:	101253025(SUS4) 101255377 101266782 101267720 543731(sus3) 543961

SPEN:

107005525 107010996 107012422 107026306 107026596 107029484

SOT:	102577575 102577594(SS16) 102577712 102582945 102586510 102588355

SSTN:

125846239 125852920 125860306 125861222 125875563 125876400

SDUL:

129870083 129872965 129882963 129882964 129892571 129892575 129894276

CANN:

107840883 107859646 107862814 107864054 107877893

LBB:	132608847 132617183 132618706 132623550 132632379 132636943

NTA:	107766404 107769655 107771392 107775584 107775654 107783276 107786515 107789130 107789131(SUSY) 107789475 107796229 107804066 107830010

NSY:	104212806 104220987 104236866 104239665 104243818 104246100

NTO:	104087069 104096609 104108826 104116253 104116323 104116324

NAU:	109206481 109208908 109214879 109226534 109228646 109242798

INI:	109160151 109167470 109170760 109172636 109187875 109190716 109192510

ITR:	115996551 116009826 116009928 116014398 116017109 116020876 116022397

SIND:

105157343 105161960 105163347 105168540 105173722 105175978

OEU:	111366090 111369510 111371440 111388038 111394205 111399809 111406368 111408336

EGT:	105950420 105954637 105956283 105970946

SSPL:

121747683 121748810 121752062 121752340 121785070 121787229 121805022 121807651

SMIL:

130988039 131007293 131022806 131026523

SHIS:

125188776 125193215 125213509 125214739

APAN:

127241914 127251466 127255233 127259108 127264149 127264733

HAN:	110868211 110887011 110894590 110909168 110937070 110942429

ECAD:

122582187 122582189 122584953 122585299 122590987 122591036 122602820

LSV:	111885089 111888768 111890876 111895013 111899116 111899117 111916035

CCAV:

112506455 112506605 112511753 112512080 112516432 112520775

DCR:	108196194 108196428 108199296 108202090 108204620 108214576 108216259 108222408

CSIN:

114260358 114260409 114271846 114272476 114289742 114294846

RVL:	131302702 131304639 131314772 131326610

AEW:	130757233 130762153 130767461 130770171 130777867 130790234 130792079

BVG:	104891266 104898912(SBSS1) 104900089 104901675

SOE:	110795334 110800655 110801596 110802994

CQI:	110684034 110689796 110708258 110711114 110715868 110721833 110727927

ATRI:

130814105 130814435 130823694 130827490 130828324

MOF:	131150868 131153294 131154240 131154928 131157276 131159768

NNU:	104590476 104598894 104606206 104606968 104607856

MING:

122065659 122066679 122074938 122078406 122084256 122091871

TSS:	122645961 122656559 122658495 122666254 122667141 122667939

PSOM:

113298313 113303188 113326623 113339936 113345466 113355249

OSA:	4331252 4332788 4333062 4335303 4335447 4340386 4343910

DOSA:

Os02t0831500-01(Os02g0831500) Os03t0340500-01(Os03g0340500) Os03t0401300-01(Os03g0401300) Os04t0249500-00(Os04g0249500) Os04t0309600-01(Os04g0309600) Os06t0194900-01(Os06g0194900) Os07t0616800-01(Os07g0616800)

OBR:	102705920 102706647 102712095 102712964 102716200 102717886

OGL:	127763134 127765692 127767368 127771776 127775904 127778463

BDI:	100820943 100821418 100836007 100839938 100840503 100841916

ATS:	109740648 109744619 109746065 109749305 109759549 109766888 109779202

TDC:	119285662 119288144 119296208 119318722 119325817 119327849 119327915 119331447 119335297 119337405 119353790 119356081 119362975 119365225

TAES:

123046325 123048524 123052082 123054180 123083644 123085854 123088341 123092190 123097521 123129210 123140133 123146364 123149843 123150330 123151259 123160342 123164468 123165873 123167316 123187938 123190070 542972 543390

TUA:	125508666 125518000 125521237 125525176 125531634 125536293 125539442 125551720

LPER:

127302408 127314287 127317859 127331575 127332423 127332665 127335947

LRD:	124673966 124681661 124685189 124685213 124698555 124702285 124702413 124702603

SBI:	110431014 110431016 8056263 8077078 8082319

ZMA:	100278478 103634623 103654087 542091 542247 542365

SITA:

101754478 101759310 101762615 101783222 101784175

SVS:	117838151 117840640 117841692 117852648 117852695

PVIR:

120647134 120652113 120652421 120668921 120669798 120690757 120690891 120698689 120702902

PHAI:

112874627 112875082 112879014 112888915 112888930

PDA:	103702434 103702464 103703639 103707262 103711450 103712592 103714824 103717684 120103914

EGU:	105042002 105045149 105053047 105055284 105056682 105057453 105058592 105058897

MUS:	103968600 103976736 103977164 103977647 103978224 103987501 103992334 103995302 103998528

ZOF:	121969154 121975103 121980242 121981702 121984153 121985571 121992446 121996391 122010305 122016627 122019937 122020157 122023544 122023723 122036098 122036396 122037258 122037810 122052153 122053395 122056643

DCT:	110092960 110103989 110110417 110111733

PEQ:	110026604 110026668 110029391 110029413 110035855

AOF:	109819760 109820065 109833647 109845351 109849688

MSIN:

131228225 131230255 131236949 131243083 131251790

NCOL:

116248903 116254170 116255119 116257343 116263220 116264050

ATR:	18428723 18445384

SMO:	SELMODRAFT_268237(SUS)

PPP:	112272772 112282689 112286164 112287296

MNG:

MNEG_8846

CSL:	COCSUDRAFT_38455

CVR:	CHLNCDRAFT_48488

APRO:

F751_2740 F751_2741

MMAI:

sS8_2015

MSZE:

MSZNOR_0282(ss)

NOC:

Noc_3068

NHL:

Nhal_3940

NWA:

Nwat_3123

NWR:	E3U44_04215

TEE:

Tel_14610

THIP:

N838_16105

TLR:	Thiosp_00203(mfpsA_1)

TFRI:

Thiofri_00400(mfpsA_1)

TWG:	Thiowin_05095(mfpsA_3)

HHC:	M911_00600

EBS:	ECTOBSL9_1141

TGR:

Tgr7_0177

APRS:

BI364_15090

AAEO:

BJI67_02135

TTC:	FOKN1_0258

THIC:

TspCOW1_24830(spsA)

NEU:	NE1214(ss2)

NET:

Neut_1079

NST:	Nstercoris_01925

NMU:	Nmul_A2266

NLC:	EBAPG3_014530

NIZ:	NNRS527_02425

SPLB:

SFPGR_05660(spsA)

AFR:

AFE_1552

AFE:	Lferr_1268

ACU:

Atc_1727

ACZ:	Acaty_c1477

AFI:	Acife_1678

AFJ:	AFERRID_23700

AFP:	K1Y48_11375

DLM:	DPPLL_17640

DAK:	DaAHT2_1336

DDU:	GF1_10940(spsA)

DML:	Dmul_00720

DSL:	Dacsa_2708

CYN:	Cyan7425_1752 Cyan7425_3916

CEP:	Cri9333_2952

TVN:	NIES2134_106950

AMR:

AM1_6048

ACAM:

HRE53_24995

TEL:

tlr1047

THN:	NK55_01920(spsA)

THEC:

FFX45_11480

LEN:	LEP3755_22370 LEP3755_51010

LBO:	LBWT_25690 LBWT_4830

KOV:	K9N68_24660

LSC:	KIK02_02155

LSK:	J5X98_20465

PSEU:

Pse7367_0339

PGX:	OA858_23900

GLP:	Glo7428_0408 Glo7428_4260

GDU:	P0S91_04390

HAO:	PCC7418_2272

ENN:	FRE64_14770

CYC:	PCC7424_3776

ARP:	NIES39_O01860

OXY:	HCG48_05910 HCG48_11845

MVAG:

D0A34_10375

LFS:	HFV01_09090

OAC:	Oscil6304_3602

ONI:	Osc7112_4334

MPRO:

BJP34_23510 BJP34_29155

PHOR:

JWS08_09515

PYH:	NEA10_04190

MIC:	Mic7113_2737 Mic7113_3751

GEI:	GEI7407_2715

GVI:	gll3607(spsA)

GLJ:

GKIL_2834

GML:	ISF26_13800

ANA:	all1059 all4985(susA)

NPU:	Npun_F1876 Npun_F4951

NOS:	Nos7107_1514 Nos7107_2802

NOP:	Nos7524_2894 Nos7524_5556

NON:	NOS3756_14120 NOS3756_17730(susA)

NFL:	COO91_03951 COO91_06208

NOE:	CLI64_11655 CLI64_26945

NSH:

GXM_00252

NED:	HUN01_05920 HUN01_33605

AVA:	Ava_2283 Ava_3753

NAZ:

Aazo_0215

ANB:	ANA_C11946(susA)

ACY:	Anacy_1886 Anacy_4232

AWA:	AA650_01555

ANN:	EH233_15730 EH233_28335

CSG:	Cylst_0728 Cylst_1832

RSIN:

B6N60_04009

HBQ:	QI031_00830 QI031_18525

CALO:

Cal7507_2215 Cal7507_5465

CALT:

Cal6303_2136

CALN:

NIES2098_43090 NIES2098_44440

CALS:

NIES3974_05240 NIES3974_21890

RIV:	Riv7116_3519 Riv7116_6202

FIS:	FIS3754_09190 FIS3754_45090 FIS3754_46950

NSP:	BMF81_02875 BMF81_03402

NSPH:

BDGGKGIB_01184(susA_1) BDGGKGIB_01317(susA_2)

DOU:	BMF77_00525

DFS:	HGD76_13405

DHT:	NG743_15545

STOQ:

K2F26_13340

AEE:	IM676_00380 IM676_18815

TOQ:	HCG51_14160 HCG51_28585

ALAX:

NIES50_21990 NIES50_61790

NCN:	BZZ01_03970 BZZ01_08900

CTHE:

Chro_5323

PLP:	Ple7327_0671 Ple7327_2003

SCS:	Sta7437_0897

STAN:

STA3757_10090

AMUC:

Pan181_07010(mfpsA_1)

MRI:	Mal4_00730(mfpsA_1)

VBL:	L21SP4_02012

MRO:

MROS_1314

DIN:	Selin_2399

DAP:	Dacet_2944

NLI:	G3M70_12410

NWT:	NSPWAT_1033(susA)

» show all

Reference

Authors

Avigad, G. and Milner, Y.

Title

UDP-glucose:fructose transglucosylase from sugar beet roots.

Journal

Methods Enzymol 8:341-345 (1966)

Reference

2 [PMID:14367373]

Authors

CARDINI CE, LELOIR LF, CHIRIBOGA J.

Title

The biosynthesis of sucrose.

Journal

J Biol Chem 214:149-55 (1955)

Reference

3 [PMID:4624446]

Authors

Delmer DP.

Title

The purification and properties of sucrose synthetase from etiolated Phaseolus aureus seedlings.

Journal

J Biol Chem 247:3822-8 (1972)

Reference

4 [PMID:5941994]

Authors

Murata T, Sugiyama T, Minamikawa T, Akazawa T.

Title

Enzymic mechanism of starch synthesis in ripening rice grains. 3. Mechanism of the sucrose-starch conversion.

Journal

Arch Biochem Biophys 113:34-44 (1966)
DOI:10.1016/0003-9861(66)90153-6

Reference

5 [PMID:10050318]

Authors

Nakai T, Konishi T, Zhang XQ, Chollet R, Tonouchi N, Tsuchida T, Yoshinaga F, Mori H, Sakai F, Hayashi T.

Title

An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11.

Journal

Plant Cell Physiol 39:1337-41 (1998)
DOI:10.1093/oxfordjournals.pcp.a029339

Reference

6 [PMID:10592030]

Authors

Porchia AC, Curatti L, Salerno GL.

Title

Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence.

Journal

Planta 210:34-40 (1999)
DOI:10.1007/s004250050651

Reference

7 [PMID:16653008]

Authors

Ross HA, Davies HV.

Title

Purification and Characterization of Sucrose Synthase from the Cotyledons of Vicia faba L.

Journal

Plant Physiol 100:1008-1013 (1992)
DOI:10.1104/pp.100.2.1008

Reference

8 [PMID:16661094]

Authors

Silvius JE, Snyder FW.

Title

Comparative Enzymic Studies of Sucrose Metabolism in the Taproots and Fibrous Roots of Beta vulgaris L.

Journal

Plant Physiol 64:1070-1073 (1979)
DOI:10.1104/pp.64.6.1070

Reference

9 [PMID:10845453]

Authors

Tanase K, Yamaki S.

Title

Purification and characterization of two sucrose synthase isoforms from Japanese pear fruit.

Journal

Plant Cell Physiol 41:408-14 (2000)
DOI:10.1093/pcp/41.4.408

Reference

10 [PMID:12773636]

Authors

Baroja-Fernandez E, Munoz FJ, Saikusa T, Rodriguez-Lopez M, Akazawa T, Pozueta-Romero J

Title

Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants.

Journal

Plant Cell Physiol 44:500-9 (2003)
DOI:10.1093/pcp/pcg062

Sequence

[sot:102577594]

Other DBs

ExplorEnz - The Enzyme Database:

2.4.1.13

IUBMB Enzyme Nomenclature:

2.4.1.13

ExPASy - ENZYME nomenclature database:

2.4.1.13

BRENDA, the Enzyme Database:

2.4.1.13

CAS:

9030-05-1

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