Entry
Name
luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase;
uridine diphosphoglucuronate-luteolin 7-O-diglucuronide glucuronosyltransferase;
UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase;
UDPglucuronate:luteolin 7-O-diglucuronide-4'-O-glucuronosyl-transferase;
LDT;
UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase (configuration-inverting)
Reaction(IUBMB)
UDP-alpha-D-glucuronate + luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] = UDP + luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide [RN:
R06828 ]
Reaction(KEGG)
Substrate
UDP-alpha-D-glucuronate [CPD:
C00167 ];
luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] [CPD:
C12632 ]
Product
UDP [CPD:
C00015 ];
luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide [CPD:
C04900 ]
Comment
The enzyme participates in the biosynthesis of luteolin triglucuronide, the major flavone found in the photosynthetically-active mesophyll of the primary leaves of Secale cereale (rye).
History
EC 2.4.1.191 created 1992, modified 2011
Pathway
ec00944 Flavone and flavonol biosynthesis
Reference
1
Authors
Schulz, M. and Weissenbock, G.
Title
3 specific UDP-glucuronate-flavone-glucuronosyl-transferases from primary leaves of Secale cereale.
Journal
Phytochemistry 27:1261-1267 (1988)
Other DBs
ExPASy - ENZYME nomenclature database: 2.4.1.191