KEGG ENZYME: 2.4.1.258

ENZYME: 2.4.1.258

Entry

EC 2.4.1.258                Enzyme

Name

dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase;
Man5GlcNAc2-PP-Dol mannosyltransferase;
ALG3;
dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase;
Not56-like protein;
Alg3 alpha-1,3-mannosyl transferase;
Dol-P-Man:Man5GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase;
dolichyl beta-D-mannosyl phosphate:D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-mannosyltransferase

Class

Transferases;
Glycosyltransferases;
Hexosyltransferases

Sysname

dolichyl beta-D-mannosyl-phosphate:alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol 3-alpha-D-mannosyltransferase (configuration-inverting)

Reaction(IUBMB)

dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol = alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + dolichyl phosphate [RN:R06258]

Reaction(KEGG)

R06258(G)

Substrate

dolichyl beta-D-mannosyl phosphate [CPD:C03862];
alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol

Product

alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol;
dolichyl phosphate [CPD:C00110]

Comment

The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl diphosphate. Early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-dolichol to Man9Glc-NAc2-PP-dolichol on the lumenal side use dolichyl beta-D-mannosyl phosphate. The first step of this assembly pathway on the luminal side of the endoplasmic reticulum is catalysed by ALG3.

History

EC 2.4.1.258 created 1976 as EC 2.4.1.130, part transferred 2011 to EC 2.4.1.258, modified 2012

Pathway

ec00510

N-Glycan biosynthesis

ec00513

Various types of N-glycan biosynthesis

ec01100

Metabolic pathways

Orthology

K03845

alpha-1,3-mannosyltransferase

Genes

HSA:	10195(ALG3)

PTR:	460886(ALG3)

PPS:	100979287(ALG3)

GGO:	101148766(ALG3)

PON:	100448751(ALG3)

NLE:	100581760(ALG3)

HMH:	116479898(ALG3)

MCC:	703087(ALG3)

MCF:	102134126(ALG3)

MTHB:

126948431

MNI:	105480123(ALG3)

CSAB:

103221139(ALG3)

CATY:

105573975(ALG3)

PANU:

101006830(ALG3)

TGE:	112618284(ALG3)

MLEU:

105541025(ALG3)

RRO:	104664632(ALG3)

RBB:	108524997(ALG3)

TFN:	117083818(ALG3)

PTEH:

111523163(ALG3)

CANG:

105514465(ALG3)

CJC:	100390805(ALG3)

SBQ:	101045776(ALG3)

CIMI:

108311074(ALG3)

CSYR:

103265067(ALG3)

MMUR:

105855769(ALG3)

LCAT:

123630325(ALG3)

PCOQ:

105807316(ALG3)

OGA:	100942989(ALG3)

MMU:	208624(Alg3)

MCAL:

110311374(Alg3)

MPAH:

110330167(Alg3)

RNO:	287983(Alg3)

MCOC:

116085725(Alg3)

ANU:	117717519(Alg3)

MUN:	110549394(Alg3)

CGE:	100772003(Alg3)

MAUA:

101831843(Alg3)

PROB:

127226971(Alg3)

PLEU:

114683317(Alg3)

MORG:

121464949(Alg3)

MFOT:

126504192

AAMP:

119824781(Alg3)

NGI:	103732650(Alg3)

HGL:	101714764(Alg3)

CPOC:

100724786(Alg3)

CCAN:

109694096(Alg3)

DORD:

105998373(Alg3)

DSP:	122098318(Alg3)

PLOP:

125352057(Alg3)

NCAR:

124993023

MMMA:

107154320(Alg3)

OCU:

100358108

OPI:	101527523(ALG3)

TUP:	102473222(ALG3)

GVR:	103593904(ALG3)

CFA:	478653(ALG3)

CLUD:

112662786(ALG3)

VVP:	112926262(ALG3)

VLG:	121477489(ALG3)

NPO:	129498822(ALG3)

AML:	100472334(ALG3)

UMR:	103676182(ALG3)

UAH:	113254352(ALG3)

UAR:	123778957(ALG3)

ELK:

111150611

LLV:

125101266

MPUF:

101674865(ALG3)

MNP:	132011991(ALG3)

MLK:	131824794(ALG3)

NVS:	122908757(ALG3)

ORO:	101377982(ALG3)

EJU:	114207156(ALG3)

ZCA:	113916697(ALG3)

MLX:	118006891(ALG3)

NSU:	110582401(ALG3)

FCA:	101087681(ALG3)

PYU:	121034083(ALG3)

PCOO:

112849710(ALG3)

PBG:	122491666(ALG3)

PVIV:

125175101(ALG3)

LRUF:

124526620

PTG:	102971503(ALG3)

PPAD:

109275223(ALG3)

PUC:

125921124

AJU:

106983810

HHV:	120238109(ALG3)

BTA:	614624(ALG3)

BOM:	102285313(ALG3)

BIU:	109557412(ALG3)

BBUB:

102402457(ALG3)

BBIS:

105000022(ALG3)

CHX:	102181899(ALG3)

OAS:	101121650(ALG3)

BTAX:

128043630(ALG3)

ODA:	120871977(ALG3)

CCAD:

122444862(ALG3)

MBEZ:

129550836(ALG3)

SSC:	100627022(ALG3)

CFR:	102504086(ALG3)

CBAI:

105063356(ALG3)

CDK:	105085886(ALG3)

VPC:	102541103(ALG3)

BACU:

103005524(ALG3)

BMUS:

118894816(ALG3)

LVE:	103084099(ALG3)

OOR:	101272032(ALG3)

DLE:	111173360(ALG3)

PCAD:

102996118(ALG3)

PSIU:

116753034(ALG3)

NASI:

112415589(ALG3)

ECB:	100059007(ALG3)

EPZ:	103554746(ALG3)

EAI:	106834523(ALG3)

MYB:	102241054(ALG3)

MYD:	102766472(ALG3)

MMYO:

118676800(ALG3)

MLF:	102418421(ALG3)

PKL:	118724345(ALG3)

EFUS:

103300644(ALG3)

MNA:	107541086(ALG3)

DRO:	112305128(ALG3)

SHON:

119004248(ALG3)

AJM:	119056434(ALG3)

PDIC:

114490914(ALG3)

PHAS:

123827272(ALG3)

MMF:	118617287(ALG3)

PPAM:

129073546(ALG3)

HAI:	109396699(ALG3)

RFQ:	117011661(ALG3)

PALE:

102890134(ALG3)

PGIG:

120592899(ALG3)

PVP:	105307072(ALG3)

RAY:	107504920(ALG3)

MJV:	108395266(ALG3)

TOD:	119257343(ALG3)

SARA:

101548640(ALG3)

LAV:	100674341(ALG3)

TMU:

101360342

ETF:	101657869(ALG3)

DNM:	101432897(ALG3)

MDO:	100025876(ALG3)

GAS:	123247575(ALG3)

SHR:	100932630(ALG3)

AFZ:

127563448

PCW:	110221182(ALG3)

OAA:	100681362(ALG3)

GGA:	424952(ALG3)

PCOC:

116235396(ALG3)

MGP:	100543165(ALG3)

CJO:	107318207(ALG3)

TPAI:

128082243(ALG3)

LMUT:

125697662(ALG3)

NMEL:

110397801(ALG3)

APLA:

101791055(ALG3)

ACYG:

106032204(ALG3)

CATA:

118247043(ALG3)

AFUL:

116492514(ALG3)

TGU:	100230731(ALG3)

LSR:	110477428(ALG3)

SCAN:

103815608(ALG3)

PMOA:

120504281(ALG3)

OTC:	121336577(ALG3)

PRUF:

121353862(ALG3)

GFR:	102039749(ALG3)

FAB:	101819823(ALG3)

OMA:	130256619(ALG3)

PHI:	102102878(ALG3)

PMAJ:

107208518(ALG3)

CCAE:

111933602(ALG3)

CCW:	104688139(ALG3)

CBRC:

103625189(ALG3)

ETL:	114060771(ALG3)

ZAB:	102064685(ALG3)

ACHL:

103805160(ALG3)

SVG:	106850402(ALG3)

MMEA:

130574120(ALG3)

HRT:	120757409(ALG3)

FPG:	101916756(ALG3)

FCH:	102050162(ALG3)

CLV:	102094667(ALG3)

EGZ:	104122229(ALG3)

NNI:	104015704(ALG3)

PCRI:

104034328(ALG3)

PLET:

104617238(ALG3)

EHS:	104506093(ALG3)

PCAO:

104046146(ALG3)

ACUN:

113483436(ALG3)

TALA:

104361301(ALG3)

AFOR:

103901550(ALG3)

ACHC:

115347167(ALG3)

HLE:	104835216(ALG3)

AGEN:

126039796

GCL:

127020129

CCRI:

104158856(ALG3)

CMAC:

104473247(ALG3)

MUI:	104548129(ALG3)

BREG:

104632271(ALG3)

FGA:	104079913(ALG3)

GSTE:

104262859(ALG3)

LDI:	104354994(ALG3)

MNB:	103771693(ALG3)

OHA:	104326456(ALG3)

NNT:	104401829(ALG3)

SHAB:

115611212(ALG3)

DPUB:

104303020(ALG3)

PGUU:

104464680(ALG3)

ACAR:

104521752(ALG3)

CPEA:

104390967(ALG3)

AVIT:

104277069(ALG3)

CVF:	104284999(ALG3)

RTD:	128911031(ALG3)

CUCA:

104057868(ALG3)

TEO:	104382642(ALG3)

BRHI:

104492955(ALG3)

AAM:	106500262(ALG3)

AROW:

112968562(ALG3)

NPD:	112952394(ALG3)

TGT:	104578248(ALG3)

DNE:	112980155(ALG3)

SCAM:

104148883(ALG3)

ASN:	102369785(ALG3)

AMJ:	102560066(ALG3)

CPOO:

109308279(ALG3)

GGN:	109287758(ALG3)

PSS:	102457770(ALG3)

CMY:	102937300(ALG3)

CCAY:

125642104(ALG3)

DCC:	119861701(ALG3)

CPIC:

101941423(ALG3)

TST:	117883346(ALG3)

CABI:

116838579(ALG3)

MRV:	120371823(ALG3)

ACS:	100561775(alg3)

ASAO:

132770455(ALG3)

PVT:	110091600(ALG3)

SUND:

121926011

PBI:	103048200(ALG3)

PMUR:

107294401(ALG3)

CTIG:

120309553(ALG3)

TSR:	106552359(ALG3)

APRI:

131200883(ALG3)

PTEX:

113451367(ALG3)

VKO:	123025606(ALG3)

PMUA:

114598066(ALG3)

PRAF:

128414843(ALG3)

ZVI:	118093587(ALG3)

HCG:	128351138(ALG3)

GJA:	107123667(ALG3)

EMC:	129332199(ALG3)

XLA:	100037243(alg3.S)

XTR:	100127746(alg3)

NPR:	108804700(ALG3)

RTEM:

120936939(ALG3)

BBUF:

120998051(ALG3)

BGAR:

122933737(ALG3) 122934427

MUO:	115478417(ALG3)

GSH:	117366661(ALG3)

DRE:	553725(alg3)

SRX:	107730451 107749127

SANH:

107660011 107692886

SGH:	107557882 107600115

CCAR:

109063669(alg3)

CAUA:

113045392 113075849 113114242

CGIB:

127934919 127951188

PTET:

122361230(alg3)

LROH:

127177210(alg3)

OMC:	131522783(alg3)

PPRM:

120495309(alg3)

RKG:	130092330(alg3)

MAMB:

125250284(alg3)

CIDE:

127525758

MASI:

127440434 127441914

TROS:

130555045(alg3)

TDW:	130418504(alg3)

MANU:

129443019(alg3)

IPU:

108280746

IFU:	128624008(alg3)

PHYP:

113533332(alg3)

SMEO:

124402853(alg3)

TFD:	113640667(alg3)

TVC:	132847030(alg3)

AMEX:

103037087(alg3)

CMAO:

118796962(alg3)

EEE:	113568455(alg3)

CHAR:

105907064(alg3)

TRU:	101070707(alg3)

TFS:	130538588(alg3)

TNG:	GSTEN00028459G001

LCO:	104935094(alg3)

NCC:	104957796(alg3)

TBEN:

117488578(alg3)

CGOB:

115022850(alg3)

PGEO:

117462287(alg3)

GACU:

117532695(alg3) 117532736

EMAC:

134866155(alg3)

ELY:	117272230(alg3)

EFO:	125902852(alg3)

PLEP:

121951113(alg3)

SLUC:

116037306(alg3)

ECRA:

117954044(alg3)

ESP:	116699187(alg3)

PFLV:

114565685(alg3)

GAT:	120815564(alg3)

PPUG:

119209405(alg3)

AFB:	129089011(alg3)

CLUM:

117746734(alg3)

PSWI:

130198585(alg3)

MSAM:

119902871(alg3)

SCHU:

122886685(alg3)

CUD:	121519641(alg3)

ALAT:

119010979(alg3)

MZE:	101479101(alg3)

ONL:	100699348(alg3)

OAU:	116323406(alg3)

OLA:	101167399(alg3)

OML:	112147515(alg3)

CSAI:

133452662(alg3)

XMA:	102230775(alg3)

XCO:	114147052(alg3)

XHE:	116716593 116716595 116716599

PRET:

103479375(alg3)

PFOR:

103148942(alg3)

PLAI:

106953689(alg3)

PMEI:

106916472(alg3)

GAF:	122841583(alg3)

PPRL:

129362100(alg3)

CVG:	107101045(alg3)

CTUL:

119798975(alg3)

GMU:	124870039(alg3)

NFU:	107384062(alg3)

KMR:	108239541(alg3)

ALIM:

106528976(alg3)

NWH:	119414586(alg3)

AOCE:

111582584(alg3)

MCEP:

125010756(alg3)

CSEM:

103395988(alg3)

POV:	109645187(alg3)

SSEN:

122760436 122778844 122780059

HHIP:

117778792(alg3)

HSP:	118117529(alg3)

SMAU:

118310759(alg3)

LCF:

108883543

SDU:	111229092(alg3)

SLAL:

111654479(alg3)

XGL:	120799092(alg3)

HCQ:	109524102(alg3)

SSCV:

125985354

SBIA:

133511506(alg3)

PEE:	133411884(alg3)

PTAO:

133488953(alg3)

BPEC:

110158566(alg3)

MALB:

109957667(alg3)

BSPL:

114844849(alg3)

SJO:	128369305(alg3)

SASA:

106600580(alg3)

STRU:

115157451 115169348

OTW:	112226542(alg3) 112260872

OMY:	110508350(alg3) 110530733

OGO:	124009717 124041654

ONE:	115102851(alg3) 115124626

OKI:	109865349(alg3) 109885732

OKE:	118373383 118394916(alg3)

SALP:

111957003 111979135

SNH:	120020124(alg3) 120056216

CCLU:

121581232(alg3)

ELS:	105021055(alg3)

SFM:	108935289(alg3)

PKI:	111847388(alg3)

AANG:

118230487(alg3)

LOC:	102686367(alg3)

PSPA:

121323704 121326846

ARUT:

117417177(alg3) 117423052

PSEX:

120536858(alg3)

LCM:	102361691(ALG3)

CMK:	103182887(alg3)

RTP:	109916296(alg3)

CPLA:

122556045(alg3)

HOC:	132821833(alg3)

LERI:

129703240(alg3)

PMRN:

116946889(ALG3)

LRJ:	133351143(ALG3)

BFO:

118430771

BBEL:

109472651

CIN:

100176327

SCLV:

120337103

SPU:

576672

LPIC:

129276410

APLC:

110978953

AJC:

117115478

SKO:

100370088

DME:	Dmel_CG4084(Alg3)

DER:

6547893

DSE:

6615760

DSI:	Dsimw501_GD25022(Dsim_GD25022)

DYA:	Dyak_GE11542

DAN:

6494688

DSR:

110176926

DPO:

4804526

DPE:

6593024

DMN:

108158679

DWI:

6652196

DGR:

6560212

DMO:	Dmoj_GI19772

DAZ:

108616984

DNV:

108654695

DHE:

111599911

CCAT:

101451105

BOD:

106624768

BDR:

105230716

RZE:	108353985 108363606

AOQ:

129244433

TDA:

119677809

MDE:

101887633

SCAC:

106087967

LCQ:

111680079

LSQ:

119610867

GFS:

119635801

ECOE:

129941184

CLON:

129612288

HIS:

119646489

AGA:

1269946

ACOZ:

120949007

AARA:

120895199

AMER:

121594307

ASTE:

118510275

AFUN:

125770663

AMOU:

128303371

AALI:

118463244

AAG:

5574793

AALB:

109415735

CQU:	CpipJ_CPIJ010838

CPII:

120418874

CNS:

116346935

BCOO:

119080440

AME:

724399

ACER:

107995893

ALAB:

122719159

ADR:

102678565

AFLR:

100863452

BIM:

100740988

BBIF:

117213763

BVK:

117234340

BVAN:

117163300

BTER:

100643648

BAFF:

126915704

BPYO:

122568673

BPAS:

132908641

FVI:

122532675

CCAL:

113464335

OBB:

114873283

OLG:

117610842

MGEN:

117230112

NMEA:

116430340

CGIG:

122397280

SOC:

105199092

MPHA:

105833095

AEC:

105152598

ACEP:

105617243

PBAR:

105433742

VEM:

105563964

HST:

105182205

DQU:

106748045

CFO:

105251420

FEX:

115239308

LHU:

105668510

PGC:

109859340

OBO:

105280429

PCF:

106784472

PFUC:

122520252

VPS:

122630613

VCRB:

124424123

VVE:

124950358

NVI:

100115752

CSOL:

105360913

TPRE:

106660221

LHT:

122504968

LBD:

127290027

MDL:

103575039

CGLO:

123259474

FAS:

105271037

DAM:

107043474

AGIF:

122851287

CINS:

118069260

VCAN:

122412576

CCIN:

107264738

NPT:

124215729

NFB:

124178038

NLO:

107226931

NVG:

124299794

AROA:

105688486

TCA:

655451

DPA:

109539990

SOY:

115882123

AGRG:

126745204

ATD:

109600158

CSET:

123319991

AGB:

108904073

LDC:

111517904

NVL:

108558978

APLN:

108743272

PPYR:

116161218

OTU:

111418690

BMOR:

101741427

BMAN:

114241636

MSEX:

115445089

DPL:	KGM_204299

BANY:

112043297

MJU:

123864859

NIQ:

126777907

VCD:

124539679

MCIX:

123664013

PMAC:

106712323

PPOT:

106111036

PXU:

106116985

PRAP:

111002964

PBX:

123717868

PNAP:

125061837

ZCE:

119830376

CCRC:

123705685

LSIN:

126971235

HAW:

110384151

HZE:

124642829

TNL:

113492747

SLIU:

111353507

OFU:

114355516

PXY:	105382453 105398112

PGW:

126381894

CFEL:

113375722 113377819

CCRN:

123305354

API:

103308067

DNX:

107172979

AGS:

114129907

RMD:

113554562

ACOO:

126843808

DVT:

126900158

BTAB:

109033224

DCI:

103504828

CLEC:

106663453

HHAL:

106681724

NLU:

111052776

HVI:

124360574

MQU:	128995053 128995161

PHU:	Phum_PHUM128470

FOC:

113202432

TPAL:

117653890

ZNE:

110833535

CSEC:

111864641

SGRE:

126331753

BROR:

134537737

IEL:

124171436

FCD:

110846318

DPX:	DAPPUDRAFT_299865

DMK:

116919159

DPZ:

124343259

PVM:

113822625

PJA:

122260348

PCHN:

125030786

PMOO:

119576205

HAME:

121861329

PCLA:

123775164

CQD:

128694224

PTRU:

123514680

ESN:

126982713

HAZT:

108680358

EAF:

111696599

LSM:

121125786

TCF:

131887338

PPOI:

119098936 119106953

DSV:

119446845

RSAN:

119389332

RMP:

119184181

VDE:

111253320

VJA:

111271896

DPTE:

113791018

DFR:

124497628

CSCU:

111622730

PTEP:

107456683

ABRU:

129968847

UDV:

129229312

SDM:

118181742

LPOL:

106474785

PMEO:

129597096

CEL:	CELE_K09E4.2(algn-3)

CBR:

CBG_20997

LOA:	LOAG_03675

TSP:

Tsp_08712

HRO:	HELRODRAFT_185299

LGI:	LOTGIDRAFT_231054

PVUL:

126826692

PCAN:

112557649

BGT:

106078344

GAE:

121390238

HRF:

124116910

HRJ:

124287112

CRG:

105346658

CVN:	111136555 111137190

CANU:

128188853

OED:

125664535

PMAX:

117345390

MCAF:

127719412

MMER:

123527234

RPHI:

132716058 132757332

DPOL:

127832217

OBI:

106874294

OSN:

115216401

LAK:

106174922

SMM:	Smp_150200

SHX:	MS3_00005373(ALG3_1)

OVI:	T265_08463

EGL:	EGR_05095 EGR_05102

NVE:

5518637

EPA:

110251455

ATEN:

116299235

ADF:

107332168

AMIL:

114965518

PDAM:

113686199

SPIS:

111328572

DGT:

114518083

XEN:

124444254

HMG:

100214877

HSY:

130614564

AQU:	100637852 100641948

ATH:	AT2G47760(ALG3)

ALY:

9318197

CRB:

17890265

CSAT:

104783359 104784524 104793766

EUS:	EUTSA_v10001458mg

BRP:

103866347

BNA:	106390417 106450414

BOE:

106337396

RSZ:

108813443

THJ:

104802172

CPAP:

110821460

CIT:

102617688

CIC:	CICLE_v10020260mg

PVY:

116139023

MINC:

123217140

TCC:

18613533

GRA:

105762674

GHI:	107929848 107940990

GAB:	108468799 108477307

HSYR:

120152062 120173689

DZI:

111314136

EGR:

104456792

GMX:	100785253 100793743

GSJ:	114400170 114407354

PVU:	PHAVU_001G205800g

VRA:

106758012

VAR:

108329708

VUN:

114186261

VUM:

124836247

CCAJ:

109812263

APRC:

113862765

MTR:

11434786

TPRA:

123892689 123897907

CAM:

101509815

PSAT:

127132684

VVO:

131610839

LJA:	Lj1g3v4899050.1(Lj1g3v4899050.1)

ADU:

107492492

AIP:

107645621

AHF:	112695809 112756385

LANG:

109331564 109331577

PCIN:

129307346

QSA:	O6P43_007155

FVE:

101310494

RCN:

112172534

PPER:

18767523

PMUM:

103333910

PAVI:

110761861

PDUL:

117637036

MDM:	103432570 103449140

MSYL:

126589764 126614327

PXB:	103934136 103934145

ZJU:

107426367

MNT:

21392434

CSAV:

115695222

CSV:

101211394

CMO:

103492832

BHJ:

120087178

MCHA:

111020823

CMAX:

111488806

CMOS:

111456562

CPEP:

111807027

RCU:

8271753

JCU:

105642496

HBR:

110660934

MESC:

110615603

POP:

7457948

PEU:

105132014

PALZ:

118041494

JRE:

109003856

CILL:

122316532

CAVE:

132170750

QSU:	112019579 112033577

QLO:

115972020

TWL:

119983571

VVI:

100253790

VRI:

117917250

SLY:

101251511

SPEN:

107029293

SOT:

102598887

SSTN:

125871518

SDUL:

129882920

CANN:

107864015

LBB:	132608987 132609582

NTA:	107792795 107810286

NSY:

104225504

NTO:

104099176

NAU:	109232022 109243184

INI:

109160269

ITR:

116014836

SIND:

105165232

OEU:

111394355

EGT:

105954033

SSPL:

121742021

SMIL:

131000456

SHIS:

125210895 125222456

APAN:

127251723

HAN:

110895982

ECAD:

122582293

LSV:

111917946

CCAV:

112513534

DCR:

108224117

CSIN:

114310377

RVL:

131315088

AEW:	130752131 130770864

BVG:

104906606

SOE:

110797544

CQI:	110703835 110720342

ATRI:

130802245

MOF:

131156152

NNU:

104610985

MING:

122064043

TSS:

122669677

PSOM:

113357561

OSA:

9266078

OBR:

102705966

OGL:

127760816

BDI:

100822122

ATS:

109779517

TDC:	119271920 119279341

TAES:

123060251 123076127

TUA:

125546644

LPER:

127341195

LRD:	124661460 124665757

SBI:

8056549

ZMA:

100276684

SITA:

101768406

SVS:

117857423

PVIR:

120672571 120705850

PHAI:

112893636

PDA:	103712729 120106333

EGU:

105060271

MUS:

103981289

ZOF:	121967403 122036790 122047205

DCT:

110101639

PEQ:

110026944

AOF:

109841030

MSIN:

131224774

NCOL:

116254698

ATR:

18430288

SMO:	SELMODRAFT_96090(GT58A1)

PPP:

112287567

CSL:	COCSUDRAFT_30276

APRO:

F751_3769

OLU:	OSTLU_47741

OTA:	OT_ostta17g01080

BPG:	Bathy06g00560

MIS:	MICPUN_68602

MPP:	MICPUCDRAFT_3334(JGI:MicpuC2_3334)

CME:	CYME_CMK113C

GSL:	Gasu_08400

CCP:	CHC_T00009519001

SCE:	YBL082C(ALG3)

SEUB:

DI49_0105

SPAO:

SPAR_B00280

AGO:	AGOS_AGL299C

ERC:

Ecym_7147

KLA:	KLLA0_E20747g

KMX:	KLMA_80379(ALG3)

LTH:	KLTH0C06314g

VPO:	Kpol_1045p31

ZRO:	ZYRO0B03696g

CGR:	CAGL0A04587g

NCS:	NCAS_0E02510(NCAS0E02510)

NDI:	NDAI_0E04080(NDAI0E04080)

TPF:	TPHA_0K00760(TPHA0K00760)

TBL:	TBLA_0D00510(TBLA0D00510)

TGB:	HG536_0B04560

TDL:	TDEL_0C02670(TDEL0C02670)

KAF:	KAFR_0L01850(KAFR0L01850)

KNG:	KNAG_0B02260(KNAG0B02260)

ZMK:	HG535_0E04460

PPA:	PAS_chr4_0712

DHA:	DEHA2A05940g

PIC:	PICST_58095(RHK1)

PGU:	PGUG_03506

SPAA:

SPAPADRAFT_63313

LEL:	PVL30_005602(ALG3)

CAL:	CAALFM_C604340WA(CaO19.1092)

CTP:	CTRG_02752

COT:	CORT_0F02090

CDU:	CD36_64690

CTEN:

CANTEDRAFT_104274

YLI:	YALI0E03190g

CLU:	CLUG_05320

CLUS:

A9F13_14g00935

CAUR:

CJI96_0001120

PKZ:	C5L36_0C09610

BNN:	FOA43_001061

BBRX:

BRETT_003635

OPA:	HPODL_04790

SLUD:

SCDLUD_000157

NCR:

NCU06552

NTE:	NEUTE1DRAFT78420(NEUTE1DRAFT_78420)

SMP:	SMAC_04688

PAN:	PODANS72p038

PBEL:

QC761_608480(ALG3)

PPSD:

QC762_608480(ALG3)

PPSP:

QC763_608480(ALG3)

PPSA:

QC764_608480(ALG3)

TTT:	THITE_32842

MTM:	MYCTH_2310419

MGR:

MGG_08010

PPEI:

PpBr36_01446

PGRI:

PgNI_03564

TMN:	UCRPA7_8118

SSCK:

SPSK_09197

FGR:	FGSG_09653

FPU:	FPSE_05935

FPOA:

FPOAC1_011994(ALG3)

FVN:	FVRRES_13062

FVR:	FVEG_06263

FOX:	FOXG_08415

NHE:	NECHADRAFT_57958

FFC:	NCS54_00231400

FKR:	NCS57_00226800

FMU:	J7337_004522(ALG3)

TRE:	TRIREDRAFT_104121

TRR:	M419DRAFT_72510

MAW:

MAC_01438

MAJ:

MAA_07040

PCHM:

VFPPC_13737

CMT:

CCM_00021

AMUS:

LMH87_012271

PLJ:	VFPFJ_06547

PTKZ:

JDV02_000015(ALG3)

VAL:	VDBG_03472

VDA:	VDAG_09914

CFJ:	CFIO01_11281

CLUP:

CLUP02_18214

CHIG:

CH63R_13579

SAPO:

SAPIO_CDS7572

ELA:	UCREL1_3732

PFY:	PFICI_04253

BFU:	BCIN_12g04720(Bcalg3)

MBE:

MBM_00831

PSCO:

LY89DRAFT_734249

GLZ:	GLAREA_09261

AFM:	AFUA_5G11990

ACT:	ACLA_015020

NFI:	NFIA_075290

AOR:	AO090120000319

ANG:	An18g02360

AFV:	AFLA_009536

ALUC:

AKAW2_31341A(ALG3)

ACHE:

ACHE_41218S(ALG3)

APUU:

APUU_12054A(ALG3)

PCS:	N7525_007182

PDP:	PDIP_59690

POU:	POX_d05305

TMF:	EYB26_001574

TRG:	TRUGW13939_05668

CIM:	CIMG_09210

CPW:	CPC735_016250

URE:	UREG_05252

PBL:	PAAG_02443

PBN:	PADG_05592

ABE:

ARB_04378

TVE:

TRV_03168

AJE:	HCAG_02634

BGH:	BDBG_07801

PNO:	SNOG_16505(SNOG_16504)

PTE:

PTT_10389

BZE:	COCCADRAFT_32716

BSC:	COCSADRAFT_32678

BOR:	COCMIDRAFT_102056

AALT:

CC77DRAFT_941634

ARAB:

EKO05_0009090

ZTR:	MYCGRDRAFT_48084

PFJ:	MYCFIDRAFT_190681

FFU:	CLAFUR5_10835

CBET:

CB0940_06798

BCOM:

BAUCODRAFT_79259

NPA:	UCRNP2_6346

TML:	GSTUM_00001398001

SPO:	SPAC7D4.06c(alg3)

SOM:	SOMG_03645(alg3)

CNE:

CNL04800

CNB:

CNBI2040

CNG:	CNAG_05142

CGI:	CGB_D2280C

CDEU:

CNBG_4549

TMS:	TREMEDRAFT_68105

TASA:

A1Q1_00798

CCAC:

CcaHIS019_0211610(ALG3)

TVS:	TRAVEDRAFT_119321

DSQ:	DICSQDRAFT_177383

PCO:	PHACADRAFT_120945

SHS:	STEHIDRAFT_50300

HIR:	HETIRDRAFT_60319

PSQ:	PUNSTDRAFT_105197

ADL:	AURDEDRAFT_81645

FME:	FOMMEDRAFT_79786

GTR:	GLOTRDRAFT_114669

RSX:	RhiXN_10823

LBC:	LACBIDRAFT_247511(ALG3)

CCI:	CC1G_13978

ABP:	AGABI1DRAFT118456(AGABI1DRAFT_118456)

ABV:	AGABI2DRAFT200258(AGABI2DRAFT_200258)

MRR:	Moror_6455

E1B28_008725

SCM:	SCHCO_02524870(SCHCODRAFT_02524870)

CPUT:

CONPUDRAFT_48179

SLA:	SERLADRAFT_475301

WSE:	WALSEDRAFT_61595

MRT:

MRET_3365

MSYM:

MSY001_3019(ALG3)

PGR:	PGTG_03346

PTRC:

PtA15_9A585

PSTR:

Pst134EA_000058

MLR:	MELLADRAFT_47521 MELLADRAFT_91322

MBR:	MONBRDRAFT_38469

SRE:	PTSG_01106

DDI:	DDB_G0268238(alg3)

DPP:	DICPUDRAFT_37084

DFA:	DFA_10860(alg3)

ACAN:

ACA1_023390

PTI:	PHATRDRAFT_10976

FCY:	FRACYDRAFT_180557(ALG3)

TPS:	THAPSDRAFT_34773

PIF:	PITG_02432

PSOJ:

PHYSODRAFT_323848

SPAR:

SPRG_04773

EHX:	EMIHUDRAFT_426313(ALG3-1) EMIHUDRAFT_521974(ALG3-2)

GTT:	GUITHDRAFT_108213

TBR:	Tb10.70.0260

TBG:	TbgDal_X7980

TCR:	510187.404

LMA:	LMJF_36_2040(ALG3)

LIF:	LINJ_36_2160(ALG3)

LDO:	LDBPK_362160

LMI:	LMXM_36_2040

LBZ:	LBRM_35_2270

LPAN:

LPMP_352120(ALG3)

» show all

Reference

1 [PMID:11308030]

Authors

Sharma CB, Knauer R, Lehle L

Title

Biosynthesis of lipid-linked oligosaccharides in yeast: the ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.

Journal

Biol Chem 382:321-8 (2001)
DOI:10.1515/BC.2001.039

Sequence

[sce:YBL082C]

Reference

2 [PMID:10660594]

Authors

Cipollo JF, Trimble RB

Title

The accumulation of Man(6)GlcNAc(2)-PP-dolichol in the Saccharomyces cerevisiae Deltaalg9 mutant reveals a regulatory role for the Alg3p alpha1,3-Man middle-arm addition in downstream oligosaccharide-lipid and glycoprotein glycan processing.

Journal

J Biol Chem 275:4267-77 (2000)
DOI:10.1074/jbc.275.6.4267

Other DBs

ExplorEnz - The Enzyme Database:

2.4.1.258

IUBMB Enzyme Nomenclature:

2.4.1.258

ExPASy - ENZYME nomenclature database:

2.4.1.258

BRENDA, the Enzyme Database:

2.4.1.258

DBGET integrated database retrieval system