Entry |
|
Name |
cellulose synthase (GDP-forming);
cellulose synthase (guanosine diphosphate-forming);
cellulose synthetase;
guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase;
guanosine diphosphoglucose-cellulose glucosyltransferase;
GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase
|
Class |
Transferases;
Glycosyltransferases;
Hexosyltransferases
|
Sysname |
GDP-alpha-D-glucose:(1->4)-beta-D-glucan 4-beta-D-glucosyltransferase (configuration-inverting)
|
Reaction(IUBMB) |
GDP-alpha-D-glucose + [(1->4)-beta-D-glucosyl]n = GDP + [(1->4)-beta-D-glucosyl]n+1 [RN: R02890 R06030]
|
Reaction(KEGG) |
|
Substrate |
GDP-alpha-D-glucose [CPD: C00394];
[(1->4)-beta-D-glucosyl]n
|
Product |
GDP [CPD: C00035];
[(1->4)-beta-D-glucosyl]n+1
|
Comment |
Involved in the synthesis of cellulose. A similar enzyme [EC 2.4.1.12, cellulose synthase (UDP-forming)] utilizes UDP-alpha-D-glucose.
|
History |
EC 2.4.1.29 created 1965
|
Pathway |
ec00500 | Starch and sucrose metabolism |
|
Reference |
|
Authors |
Chambers J, Elbein AD. |
Title |
Biosynthesis of glucans in mung bean seedlings. Formation of beta-(1,4)-glucans from GDP-glucose and beta-(1,3)-glucans from UDP-glucose. |
Journal |
|
Reference |
|
Authors |
Flowers HM, Batra KK, Kemp J, Hassid WZ. |
Title |
Biosynthesis of cellulose in vitro from guanosine diphosphate D-glucose with enzymic preparations from Phaseolus aureus and Lupinus albus. |
Journal |
J Biol Chem 244:4969-74 (1969) |
Other DBs |
ExplorEnz - The Enzyme Database: | 2.4.1.29 |
ExPASy - ENZYME nomenclature database: | 2.4.1.29 |
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