KEGG ENZYME: 2.4.1.44

ENZYME: 2.4.1.44

Entry

EC 2.4.1.44                 Enzyme

Name

lipopolysaccharide 3-alpha-galactosyltransferase;
UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase;
UDP-galactose:polysaccharide galactosyltransferase;
uridine diphosphate galactose:lipopolysaccharide alpha-3-galactosyltransferase;
uridine diphosphogalactose-lipopolysaccharide alpha,3-galactosyltransferase;
UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase

Class

Transferases;
Glycosyltransferases;
Hexosyltransferases

Sysname

UDP-alpha-D-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase

Reaction(IUBMB)

UDP-alpha-D-galactose + lipopolysaccharide = UDP + 3-alpha-D-galactosyl-[lipopolysaccharide glucose] [RN:R01997]

Reaction(KEGG)

R01997

Substrate

UDP-alpha-D-galactose [CPD:C00052];
lipopolysaccharide [CPD:C00338]

Product

UDP [CPD:C00015];
3-alpha-D-galactosyl-[lipopolysaccharide glucose] [CPD:C04473]

Comment

Transfers alpha-D-galactosyl residues to D-glucose in the partially completed core of lipopolysaccharide [cf. EC 2.4.1.56 (lipopolysaccharide N-acetylglucosaminyltransferase), EC 2.4.1.58 (lipopolysaccharide glucosyltransferase I) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)].

History

EC 2.4.1.44 created 1972, modified 2002

Orthology

K03278

UDP-D-galactose:(glucosyl)LPS alpha-1,3-D-galactosyltransferase

Genes

STY:	STY4077(waaI)

STT:	t3801(waaI)

SEX:	STBHUCCB_40120

SENT:

TY21A_19310

STM:	STM3718(rfaI)

SEO:	STM14_4479(rfaI)

SEV:	STMMW_37071

SEY:	SL1344_3684(rfaI)

SEM:	STMDT12_C37750

SEJ:	STMUK_3704(rfaI)

SEB:	STM474_3891(rfaI)

SEF:	UMN798_4038(rfaI)

SETU:

STU288_18785

SETC:

CFSAN001921_21855

SENR:

STMDT2_36041(rfaI)

SEND:

DT104_37021(waaI)

SENI:

CY43_19290

SEEN:

SE451236_02330

SPT:	SPA3570(waaI)

SEK:

SSPA3333

SPQ:	SPAB_04615

SEI:	SPC_3800(waaI)

SEC:	SCH_3641(rfaI)

SEH:	SeHA_C4043

SHB:

SU5_04195

SENH:

CFSAN002069_13450

SEEH:

SEEH1578_04675

SEE:	SNSL254_A3998

SENN:

SN31241_1620

SEW:	SeSA_A3917

SEA:	SeAg_B3936

SENS:

Q786_18180

SED:

SeD_A4105

SEG:	SG3713(rfaI)

SEL:	SPUL_3846(rfaI)

SEGA:

SPUCDC_3832(rfaI)

SET:	SEN3540(rfaI)

SENA:

AU38_18080

SENO:

AU37_18270

SENV:

AU39_18275

SENQ:

AU40_20360

SENL:

IY59_18715

SENJ:

CFSAN001992_15060

SEEC:

CFSAN002050_25560

SEEB:

SEEB0189_001275

SEEP:

I137_18450

SENB:

BN855_38130

SENE:

IA1_18075

SENC:

SEET0819_02350

SES:	SARI_03923

SBG:	SBG_3300(waaI)

SBZ:

A464_3795

SBV:	N643_16410

SALZ:

EOS98_00645

CSED:

JY391_00575(waaO)

CAMA:

F384_19595

CAF:	AL524_02360

CFAR:

CI104_00570

CIR:	C2U53_08990

CTEL:

GBC03_03770(waaO)

KCO:	BWI95_08435

KOT:	EH164_00520

KOB:	HF650_00630(waaO)

KIE:	NCTC12125_03936(rfaJ_1)

BAGE:

BADSM9389_41080

PLAR:

GII40_00124(gspA)

PSGC:

G163CM_37060(gspA)

SCOL:

KFZ77_18430(waaO)

EBF:

D782_0097

PQU:	IG609_019395(waaO)

PHAG:

PZ638_20490(waaO)

AED:	E3U36_01245

AET:	LDL57_00550

AAPC:

QG404_00670 QG404_01675(waaO) QG404_06615

» show all

Reference

1 [PMID:4898284]

Authors

Endo A, Rothfield L.

Title

Studies of a phospholipid-requiring bacterial enzyme. I. Purification and properties of uridine diphosphate galactose: lipopolysaccharide alpha-3-galactosyl transferase.

Journal

Biochemistry 8:3500-7 (1969)
DOI:10.1021/bi00837a003

Reference

2 [PMID:6403519]

Authors

Wollin R, Creeger ES, Rothfield LI, Stocker BA, Lindberg AA.

Title

Salmonella typhimurium mutants defective in UDP-D-galactose:lipopolysaccharide alpha 1,6-D-galactosyltransferase. Structural, immunochemical, and enzymologic studies of rfaB mutants.

Journal

J Biol Chem 258:3769-74 (1983)

Other DBs

ExplorEnz - The Enzyme Database:

2.4.1.44

IUBMB Enzyme Nomenclature:

2.4.1.44

ExPASy - ENZYME nomenclature database:

2.4.1.44

BRENDA, the Enzyme Database:

2.4.1.44

CAS:

9073-98-7

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