KEGG   ENZYME: 2.4.1.48
Entry
EC 2.4.1.48                 Enzyme                                 
Name
heteroglycan alpha-mannosyltransferase;
GDP mannose alpha-mannosyltransferase;
guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase
Reaction(IUBMB)
GDP-mannose + heteroglycan = GDP + 2(or 3)-alpha-D-mannosyl-heteroglycan [RN:R03768 R03769]
Reaction(KEGG)
R03768 R03769
Substrate
GDP-mannose [CPD:C00096];
heteroglycan [CPD:C01923]
Product
GDP [CPD:C00035];
2-alpha-D-mannosyl-heteroglycan [CPD:C04097];
3-alpha-D-mannosyl-heteroglycan [CPD:C04098]
Comment
The acceptor is a heteroglycan primer containing mannose, galactose and xylose. 1,2- and 1,3-mannosyl bonds are formed.
History
EC 2.4.1.48 created 1972
Reference
1  [PMID:5492958]
  Authors
Garancis JC, Ankel H, Ankel E, Schutzbach JS.
  Title
Mannosyl transfer in Cryptococcus laurentii.
  Journal
J Biol Chem 245:3945-55 (1970)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.48
IUBMB Enzyme Nomenclature: 2.4.1.48
ExPASy - ENZYME nomenclature database: 2.4.1.48
BRENDA, the Enzyme Database: 2.4.1.48
CAS: 37277-57-9

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