| Entry |
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| Name |
2-aminoethylphosphonate---pyruvate transaminase;
(2-aminoethyl)phosphonate transaminase;
(2-aminoethyl)phosphonate aminotransferase;
(2-aminoethyl)phosphonic acid aminotransferase;
2-aminoethylphosphonate-pyruvate aminotransferase;
2-aminoethylphosphonate aminotransferase;
2-aminoethylphosphonate transaminase;
AEP transaminase;
AEPT
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| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
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| Sysname |
(2-aminoethyl)phosphonate:pyruvate aminotransferase
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| Reaction(IUBMB) |
(2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde + L-alanine [RN: R04152]
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| Reaction(KEGG) |
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| Substrate |
(2-aminoethyl)phosphonate [CPD: C03557];
pyruvate [CPD: C00022]
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| Product |
2-phosphonoacetaldehyde [CPD: C03167];
L-alanine [CPD: C00041]
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| Comment |
A pyridoxal-phosphate protein. 2-Aminoethylarsonate can replace 2-aminoethylphosphonate as a substrate.
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| History |
EC 2.6.1.37 created 1972, modified 1982, modified 2001
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| Pathway |
| ec00440 | Phosphonate and phosphinate metabolism |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K03430 | 2-aminoethylphosphonate-pyruvate transaminase |
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| Genes |
| SMW: | SMWW4_v1c21470(phnW) |
| SFJ: | SAMEA4384070_2177(phnW) |
| PHEI: | NCTC12003_03585(phnW) |
| VCE: | Vch1786_II0289(phnW) |
| VPL: | SA104470976_03364(phnW) |
| VSA: | VSAL_I1817 VSAL_II0812 |
| PAEB: | NCGM1900_5263(phnW) |
| PPRC: | PFLCHA0_c40240(phnW) |
| PPZ: | H045_01940 H045_11685 |
| PMAN: | OU5_0005 OU5_1264(phnW) |
| PFW: | PF1751_v1c33490(phnW) |
| PPUU: | PputUW4_01746(phnW1) PputUW4_02575(phnW2) |
| PFK: | PFAS1_02045 PFAS1_24590 |
| PSIL: | PMA3_08190 PMA3_19075 |
| PUM: | HGP31_10035 HGP31_20440 |
| PAZE: | KSS91_14155 KSS91_18855 |
| PTW: | TUM18999_09420(phnW) |
| PTAE: | NCTC10697_03154(phnW) |
| PIZ: | LAB08_R22300 LAB08_R40060 |
| PSY: | PCNPT3_05535 PCNPT3_09905 |
| MYA: | MORIYA_1338 MORIYA_2357 MORIYA_2610(phnW) |
| AEL: | NCTC12917_03271(phnW) |
| REH: | H16_B1953(h16_B1953) |
| REU: | Reut_B3718 Reut_B5871 |
| COX: | E0W60_03315 E0W60_18825 |
| CCAM: | M5D45_07515 M5D45_24775 |
| BMA: | BMAA0852 BMAA1770(phnW) |
| BMV: | BMASAVP1_0760(phnW) BMASAVP1_1756 |
| BML: | BMA10229_1053(phnW) BMA10229_2208 |
| BMN: | BMA10247_A0895 BMA10247_A2028(phnW) |
| BMAI: | DM57_07155 DM57_09835 |
| BMAF: | DM51_3463 DM51_4548(phnW) |
| BMAZ: | BM44_3972 BM44_4878(phnW) |
| BMAB: | BM45_3780(phnW) BM45_4749 |
| BPM: | BURPS1710b_A1899(phnW) BURPS1710b_A2063(phnW) |
| BPL: | BURPS1106A_A0485(phnW) BURPS1106A_A0689(phnW) |
| BPD: | BURPS668_A0582(phnW) BURPS668_A0778 |
| BPSE: | BDL_3575(phnW) BDL_3733 |
| BPSM: | BBQ_5689 BBQ_5856(phnW) |
| BPSU: | BBN_3739(phnW) BBN_3907 |
| BPSD: | BBX_5413(phnW) BBX_5570 |
| BPZ: | BP1026B_II0373 BP1026B_II0562 |
| BPQ: | BPC006_II0462 BPC006_II0733 |
| BPK: | BBK_5555(phnW) BBK_5712 |
| BPSH: | DR55_4845 DR55_5004(phnW) |
| BPSA: | BBU_5540 BBU_5774(phnW) |
| BPSO: | X996_4595 X996_4773(phnW) |
| BUT: | X994_4113 X994_4273(phnW) |
| BTE: | BTH_II1910 BTH_II2055(phnW) |
| BTQ: | BTQ_5192 BTQ_5335(phnW) |
| BTJ: | BTJ_3822 BTJ_3987(phnW) |
| BTZ: | BTL_4678 BTL_4811(phnW) |
| BTD: | BTI_4387(phnW) BTI_5336 |
| BTV: | BTHA_5419(phnW) BTHA_5551 |
| BTHE: | BTN_4317 BTN_4461(phnW) |
| BTHM: | BTRA_4582 BTRA_4726(phnW) |
| BTHA: | DR62_4366 DR62_4575 |
| BTHL: | BG87_4649 BG87_4792(phnW) |
| BOK: | DM82_2523 DM82_4418(phnW) DM82_4609 |
| BOC: | BG90_2210 BG90_5982 BG90_6152(phnW) |
| BUU: | WS70_19210 WS70_20045 |
| BSAV: | WS86_03970 WS86_20555 WS86_21230 |
| BHG: | I6G56_25505 I6G56_31130 |
| BUD: | AQ610_21305 AQ610_28110 |
| BVI: | Bcep1808_3549 Bcep1808_4685 |
| BVE: | AK36_3210(phnW) AK36_4234 |
| BUR: | Bcep18194_A6497 Bcep18194_B0347 Bcep18194_B1916 |
| BCM: | Bcenmc03_3162 Bcenmc03_3400 Bcenmc03_4967 |
| BCH: | Bcen2424_4119 Bcen2424_5301 |
| BCJ: | BCAL0446 BCAM1243 BCAM2499 |
| BCEN: | DM39_3248(phnW) DM39_3755 DM39_5338(phnW) |
| BCEW: | DM40_3151(phnW) DM40_4161 |
| BCEO: | I35_3219 I35_5092 I35_6399 |
| BAC: | BamMC406_4014 BamMC406_5190 |
| BMJ: | BMULJ_00091(phnW) BMULJ_04037 BMULJ_05106(phnW) |
| BMU: | Bmul_3138 Bmul_3422 Bmul_4473 |
| BMK: | DM80_1716(phnW) DM80_3634 DM80_4805(phnW) |
| BMUL: | NP80_118(phnW) NP80_4146 NP80_5127(phnW) |
| BCT: | GEM_0286 GEM_4497 GEM_5896 |
| BCED: | DM42_1812(phnW) DM42_3848 DM42_5475(phnW) |
| BCEP: | APZ15_18460 APZ15_23050 |
| BDL: | AK34_3330(phnW) AK34_4232 |
| BPYR: | ABD05_23060 ABD05_29925 |
| BCON: | NL30_06380 NL30_16325 NL30_28890 |
| BUB: | BW23_3720(phnW) BW23_4917 |
| BDF: | WI26_15245 WI26_19315 WI26_25315 |
| BLAT: | WK25_23140 WK25_28345 |
| BTEI: | WS51_03910 WS51_09450 WS51_26140 |
| BSEM: | WJ12_15770 WJ12_26075 WJ12_32555 |
| BPSL: | WS57_01620 WS57_07800 WS57_34570 |
| BMEC: | WJ16_15960 WJ16_24700 WJ16_31030 |
| BSTG: | WT74_25005 WT74_31380 |
| BSTL: | BBJ41_12755 BBJ41_19205 BBJ41_26475 |
| BANN: | JFN94_16105 JFN94_16860 JFN94_23420 |
| BARI: | NLX30_17980 NLX30_24615 NLX30_32420 |
| BAEN: | L3V59_17925 L3V59_19225 L3V59_27485 |
| BGL: | bglu_2g03890 bglu_2g13480 |
| BGU: | KS03_4593 KS03_5531(phnW) |
| BUG: | BC1001_1572 BC1001_5205 BC1001_PA6461(phnW) |
| BGD: | bgla_2g05600 bgla_2g13340 |
| BGO: | BM43_4190(phnW) BM43_5001 |
| BUE: | BRPE67_ACDS06770(phnW) |
| BUL: | BW21_3920(phnW) BW21_5016 |
| BUQ: | AC233_08585 AC233_24000 |
| BGP: | BGL_2c04810(phnW1) BGL_2c11750 BGL_2c20320(phnW2) |
| BPLA: | bpln_2g05360 bpln_2g12590 bpln_2g20570 |
| BUM: | AXG89_10170 AXG89_18200 |
| BUI: | AX768_03895 AX768_27975 |
| BURK: | DM992_19625 DM992_24180 |
| BXE: | Bxe_A2116 Bxe_B1876 Bxe_B2233 |
| BXB: | DR64_4271(phnW) DR64_4564 DR64_7186(phnW) |
| BPH: | Bphy_3820 Bphy_5064 Bphy_7778 |
| BGE: | BC1002_1613 BC1002_3395 BC1002_6647 |
| BPX: | BUPH_02084 BUPH_04749 BUPH_05876 |
| BPY: | Bphyt_2142 Bphyt_5997 |
| BUZ: | AYM40_09625 AYM40_23420 AYM40_24055 |
| BFN: | OI25_3688(phnW) OI25_4334(phnW) OI25_4866(phnW) |
| BCAI: | K788_0000149 K788_0006023 K788_0008329 |
| PSPW: | BJG93_04365 BJG93_18650 |
| PARA: | BTO02_27445 BTO02_27700 |
| PARB: | CJU94_14615 CJU94_32430 |
| PHS: | C2L64_27760 C2L64_30750 C2L64_33600 |
| PTER: | C2L65_20740 C2L65_27410 C2L65_30180 |
| PGP: | CUJ91_09200 CUJ91_19565 |
| PCJ: | CUJ87_08630 CUJ87_30250 |
| PCAF: | DSC91_002022 DSC91_003380 |
| PMEG: | FNZ07_08540 FNZ07_09275 |
| PTRO: | G5S35_07175 G5S35_19390 |
| PGIS: | I6I06_03895 I6I06_19285 |
| PACP: | FAZ97_07010 FAZ97_15200 |
| PACS: | FAZ98_06870 FAZ98_20215 |
| PEW: | KZJ38_30045 KZJ38_30300 |
| PDIO: | PDMSB3_0867.1(phnW) PDMSB3_1174.1(phnW) PDMSB3_2223(phnW) |
| PBRY: | NDK50_10820 NDK50_30790 NDK50_32640 |
| PSAA: | QEN71_14445 QEN71_20810 QEN71_21255 QEN71_42300 QEN71_42495 |
| PKF: | RW095_11990 RW095_28635 |
| PPAI: | E1956_10560 E1956_20715 E1956_23905 E1956_38190 |
| PPK: | U875_16975 U875_20750 |
| PPNO: | DA70_09045 DA70_13440 |
| PPNM: | LV28_17260 LV28_21760 |
| PRB: | X636_13425 X636_17445 |
| PPUL: | RO07_11385 RO07_16150 |
| PSPU: | NA29_07205 NA29_21000 |
| PAPI: | SG18_00150 SG18_11765 |
| PVE: | UC34_03080 UC34_07410 |
| POX: | MB84_07580 MB84_11750 |
| PFG: | AB870_14295 AB870_18100 |
| PNR: | AT302_11230 AT302_26655 |
| PAND: | DRB87_02870 DRB87_06670 |
| PFIB: | PI93_002810 PI93_020435 |
| PCOM: | NTU39_03470 NTU39_08420 |
| CABA: | SBC2_17310(phnW_1) SBC2_67620(phnW_3) |
| AXX: | ERS451415_00878(phnW) |
| LIM: | L103DPR2_01223(phnW) |
| URU: | DSM104443_01252(phnW) |
| UPL: | DSM104440_01175(phnW) |
| SMEL: | SM2011_b21537(phnW) |
| RGI: | RGI145_04325 RGI145_09775 |
| ROS: | CTJ15_07655 CTJ15_13080 |
| RMUC: | FOB66_06125 FOB66_09680 |
| RMT: | IAI58_00090 IAI58_18625 |
| RAP: | RHOA_1799(phnW) RHOA_2674(phnW) |
| BMQ: | BMQ_0786 BMQ_3212(phnW) |
| BMD: | BMD_0787 BMD_3230(phnW) |
| NMK: | CHR53_02230(phnW) CHR53_16905(phnW) |
| BLEN: | NCTC4824_00279(phnW) |
| BOU: | I5818_22330 I5818_25590(phnW) |
| BCHS: | JNE38_23190(phnW) JNE38_24260(phnW) |
| BPAB: | PSE45_21075(phnW) PSE45_21750(phnW) |
| BBOR: | RFB14_06015(phnW) RFB14_13255(phnW) |
| PKB: | B4V02_00185 B4V02_16740 |
| PAIH: | ASL14_05450 ASL14_12575 |
| PLUT: | EI981_01415(phnW) EI981_13665 |
| PCHI: | PC41400_18305 PC41400_27610(phnW) |
| ADAU: | NZD86_17990(phnW) NZD86_21660 |
| EFU: | HMPREF0351_11688(phnW) |
| CBUT: | ATN24_05950 ATN24_15825 |
| BPRO: | PMF13cell1_01420(phnW) |
| BHV: | BLHYD_07740(phnW_1) BLHYD_27410(phnW_2) BLHYD_29910(phnW_3) |
| ETM: | CE91St48_24890(phnW) |
| CDF: | CD630_07400 CD630_28490(phnXW) |
| PDC: | CDIF630_00856 CDIF630_03116(phnXW) |
| CDC: | CD196_0687 CD196_2693 |
| CDL: | CDR20291_0668 CDR20291_2740 |
| PDF: | CD630DERM_07400 CD630DERM_28490(phnXW) |
| PHX: | KGNDJEFE_02124(phnW) |
| TBW: | NCTC13354_01319(phnW) |
| OBG: | Verru16b_03223(phnW) |
| BTHO: | Btheta7330_01297(phnW) |
| BFS: | BF9343_1816(aepZ) BF9343_3396 |
| BFG: | BF638R_1869 BF638R_3511 |
| BCEL: | BcellWH2_05389(phnW) |
| COPR: | Cop2CBH44_14000(phnW) |
| AALG: | AREALGSMS7_02095(phnW) |
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| Reference |
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| Authors |
La Nauze JM, Rosenberg H. |
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| Title |
The identification of 2-phosphonoacetaldehyde as an intermediate in the degradation of 2-aminoethylphosphonate by Bacillus cereus. |
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| Journal |
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| Reference |
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| Authors |
Dumora C, Lacoste AM, Cassaigne A. |
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| Title |
Purification and properties of 2-aminoethylphosphonate:pyruvate aminotransferase from Pseudomonas aeruginosa. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Lacoste AM, Dumora C, Balas L, Hammerschmidt F, Vercauteren J. |
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| Title |
Stereochemistry of the reaction catalysed by 2-aminoethylphosphonate aminotransferase. A 1H-NMR study. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Lacoste AM, Dumora C, Ali BR, Neuzil E, Dixon HB. |
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| Title |
Utilization of 2-aminoethylarsonic acid in Pseudomonas aeruginosa. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.6.1.37 |
| ExPASy - ENZYME nomenclature database: | 2.6.1.37 |
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