KEGG   ENZYME: 2.6.1.43
Entry
EC 2.6.1.43                 Enzyme                                 
Name
aminolevulinate transaminase;
aminolevulinate aminotransferase;
gamma,delta-dioxovalerate aminotransferase;
gamma,delta-dioxovaleric acid transaminase;
4,5-dioxovalerate aminotransferase;
4,5-dioxovaleric acid transaminase;
4,5-dioxovaleric transaminase;
5-aminolevulinic acid transaminase;
alanine-gamma,delta-dioxovalerate aminotransferase;
alanine-dioxovalerate aminotransferase;
alanine:4,5-dioxovalerate aminotransferase;
aminolevulinic acid transaminase;
dioxovalerate transaminase;
L-alanine-4,5-dioxovalerate aminotransferase;
L-alanine:4,5-dioxovaleric acid transaminase;
L-alanine:dioxovalerate transaminase;
DOVA transaminase;
4,5-dioxovaleric acid aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
Sysname
5-aminolevulinate:pyruvate aminotransferase
Reaction(IUBMB)
5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine [RN:R02271]
Reaction(KEGG)
R02271
Substrate
5-aminolevulinate [CPD:C00430];
pyruvate [CPD:C00022]
Product
4,5-dioxopentanoate [CPD:C02800];
L-alanine [CPD:C00041]
Comment
A pyridoxal-phosphate protein.
History
EC 2.6.1.43 created 1972
Pathway
ec00860  Porphyrin metabolism
Reference
1  [PMID:13898421]
  Authors
GIBSON KD, MATTHEW M, NEUBERGER A, TAIT GH.
  Title
Biosynthesis of porphyrins and chlorophylls.
  Journal
Nature 192:204-8 (1961)
DOI:10.1038/192204a0
Reference
2  [PMID:13938132]
  Authors
NEUBERGER A, TURNER JM.
  Title
gamma,delta-Dioxovalerate aminotransferase activity in Rhodopseudomonas spheroides.
  Journal
Biochim Biophys Acta 67:342-5 (1963)
DOI:10.1016/0006-3002(63)91839-0
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.43
IUBMB Enzyme Nomenclature: 2.6.1.43
ExPASy - ENZYME nomenclature database: 2.6.1.43
BRENDA, the Enzyme Database: 2.6.1.43
CAS: 9012-46-8

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