Entry
Name
nicotianamine aminotransferase;
NAAT;
NAAT-I;
NAAT-II;
NAAT-III;
nicotianamine transaminase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
nicotianamine:2-oxoglutarate aminotransferase
Reaction(IUBMB)
nicotianamine + 2-oxoglutarate = 3''-deamino-3''-oxonicotianamine + L-glutamate [RN:
R07277 ]
Reaction(KEGG)
Substrate
Product
3''-deamino-3''-oxonicotianamine [CPD:
C15486 ];
L-glutamate [CPD:
C00025 ]
Comment
A pyridoxal-phosphate protein. This enzyme is produced by grasses. They secrete both the nicotianamine and the transaminated product into the soil around them. Both compounds chelate iron(II) and iron(III); these chelators, called mugineic acid family phytosiderophores, are taken up by the grass, which is thereby supplied with iron.
History
EC 2.6.1.80 created 2005
Pathway
ec00999 Biosynthesis of various plant secondary metabolites
ec01110 Biosynthesis of secondary metabolites
Orthology
K14271 nicotianamine aminotransferase
Genes
DOSA : Os02t0306401-00(Os02g0306401)
TDC : 119283036 119283052 119348169 119348182
TAES : 123059564 123093828 123136500 123154591 123182310 123182311
LPER : 127318045 127334708
PVIR : 120655531 120655609 120699474
» show all
Taxonomy
Reference
1
Authors
Kanazawa, K., Higuchi, K., Nishizawa, N.-K., Fushiya, S., Chino, M. and Mori, S.
Title
Nicotianamine aminotransferase activities are correlated with the phytosiderophore secretions under Fe-deficient conditions in Gramineae.
Journal
J Exp Bot 45:1903-1906 (1994)
Reference
Authors
Takahashi M, Yamaguchi H, Nakanishi H, Shioiri T, Nishizawa NK, Mori S
Title
Cloning two genes for nicotianamine aminotransferase, a critical enzyme in iron acquisition (Strategy II) in graminaceous plants.
Journal
Sequence
Reference
Authors
Schaaf G, Ludewig U, Erenoglu BE, Mori S, Kitahara T, von Wiren N.
Title
ZmYS1 functions as a proton-coupled symporter for phytosiderophore- and nicotianamine-chelated metals.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.80
ExPASy - ENZYME nomenclature database: 2.6.1.80