KEGG ENZYME: 2.7.7.79

ENZYME: 2.7.7.79

Entry

EC 2.7.7.79                 Enzyme

Name

tRNAHis guanylyltransferase;
histidine tRNA guanylyltransferase;
Thg1p (ambiguous);
Thg1 (ambiguous)

Class

Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases

Sysname

p-tRNAHis:GTP guanylyltransferase (ATP-hydrolysing)

Reaction(IUBMB)

p-tRNAHis + ATP + GTP + H2O = pGp-tRNAHis + AMP + 2 diphosphate (overall reaction);
(1a) p-tRNAHis + ATP = App-tRNAHis + diphosphate;
(1b) App-tRNAHis + GTP = pppGp-tRNAHis + AMP;
(1c) pppGp-tRNAHis + H2O = pGp-tRNAHis + diphosphate

Substrate

p-tRNAHis;
ATP [CPD:C00002];
GTP [CPD:C00044];
H2O [CPD:C00001];
App-tRNAHis;
pppGp-tRNAHis

Product

pGp-tRNAHis;
AMP [CPD:C00020];
diphosphate [CPD:C00013];
App-tRNAHis;
pppGp-tRNAHis

Comment

In eukarya an additional guanosine residue is added post-transcriptionally to the 5'-end of tRNAHis molecules. The addition occurs opposite a universally conserved adenosine73 and is thus the result of a non-templated 3'-5' addition reaction. The additional guanosine residue is an important determinant for aminoacylation by EC 6.1.1.21, histidine---tRNA ligase.The enzyme requires a divalent cation for activity [2]. ATP activation is not required when the substrate contains a 5'-triphosphate (ppp-tRNAHis) [3].

History

EC 2.7.7.79 created 2011

Orthology

K10761

tRNA(His) guanylyltransferase

Genes

HSA:	54974(THG1L)

PTR:	462226(THG1L)

PPS:	100985901(THG1L)

GGO:	101136725(THG1L)

PON:	100433264(THG1L)

NLE:	100602201(THG1L)

HMH:	116471774(THG1L)

MCC:	715853(THG1L)

MCF:	102115652(THG1L)

MTHB:

126956740

MNI:	105482362(THG1L)

CSAB:

103244877(THG1L)

CATY:

105581565(THG1L)

PANU:

101023046(THG1L) 116273266

TGE:	112626852(THG1L)

MLEU:

105529531(THG1L)

RRO:	104662395(THG1L)

RBB:	108518389(THG1L)

TFN:	117065551(THG1L)

PTEH:

111547170(THG1L)

CANG:

105515776(THG1L)

CJC:	100392376(THG1L)

SBQ:	101054088(THG1L)

CIMI:

108295050(THG1L)

CSYR:

103257757(THG1L)

MMUR:

105880495(THG1L)

LCAT:

123638018(THG1L)

PCOQ:

105815237(THG1L)

OGA:	100965237(THG1L)

MMU:	66628(Thg1l)

MCAL:

110305178(Thg1l)

MPAH:

110332082(Thg1l)

RNO:	303067(Thg1l)

MCOC:

116078357(Thg1l)

ANU:	117710829(Thg1l)

MUN:	110557207(Thg1l)

CGE:	100763395(Thg1l)

MAUA:

101841181(Thg1l)

PROB:

127219394(Thg1l)

PLEU:

114689823(Thg1l)

MORG:

121463799(Thg1l)

MFOT:

126499453

AAMP:

119812392(Thg1l)

NGI:	103745469(Thg1l)

HGL:	101705954(Thg1l)

CPOC:

100731482(Thg1l)

CCAN:

109696233(Thg1l)

DORD:

105996798(Thg1l)

DSP:	122125042(Thg1l)

PLOP:

125342087(Thg1l)

NCAR:

124986968

MMMA:

107148072(Thg1l)

OCU:

100353509

OPI:	101530939(THG1L)

TUP:	102469988(THG1L)

GVR:	103600571(THG1L)

CFA:	479315(THG1L)

CLUD:

112651333(THG1L)

VVP:	112926763(THG1L)

VLG:	121486158(THG1L)

NPO:	129509996(THG1L)

AML:	100476440(THG1L)

UMR:	103664539(THG1L)

UAH:	113264024(THG1L)

UAR:	123788542(THG1L)

ELK:

111141075

LLV:

125100809

MPUF:

101680089(THG1L)

MNP:	132028365(THG1L)

MLK:	131831837(THG1L)

NVS:	122893488(THG1L)

ORO:	101376826(THG1L)

EJU:	114211987(THG1L)

ZCA:	113929135(THG1L)

MLX:	118016063(THG1L)

NSU:	110587413(THG1L)

LWW:	102733443(THG1L)

FCA:	101080614(THG1L)

PYU:	121009921(THG1L)

PCOO:

112861163(THG1L)

PBG:	122493112(THG1L)

PVIV:

125176312(THG1L)

LRUF:

124520785

PTG:	102957279(THG1L)

PPAD:

109276023(THG1L)

PUC:

125934493

AJU:

106967626

HHV:	120243331(THG1L)

BTA:	507084(THG1L)

BOM:	102269225(THG1L)

BIU:	109562254(THG1L)

BBUB:

102390195(THG1L)

BBIS:

104999725(THG1L)

CHX:	102177794(THG1L)

OAS:	101113674(THG1L)

BTAX:

128051466(THG1L)

ODA:	120864382(THG1L)

CCAD:

122439630(THG1L)

MBEZ:

129559255(THG1L)

SSC:	100521164(THG1L)

CFR:	102513875(THG1L)

CBAI:

105080931(THG1L)

CDK:	105095137(THG1L)

VPC:	102542813(THG1L)

BACU:

103012052(THG1L)

BMUS:

118893433(THG1L)

LVE:	103089991(THG1L)

OOR:	101281191(THG1L)

DLE:	111183160(THG1L)

PCAD:

102973236(THG1L)

PSIU:

116752030(THG1L)

NASI:

112409819(THG1L)

ECB:	100071194(THG1L)

EPZ:	103547696(THG1L)

EAI:	106832134(THG1L)

MYB:	102250438(THG1L)

MYD:	102771832(THG1L)

MMYO:

118658838(THG1L)

MLF:	102439109(THG1L)

PKL:	118711704(THG1L)

EFUS:

103291603(THG1L)

MNA:	107534435(THG1L)

DRO:	112319575(THG1L)

SHON:

119001834(THG1L)

AJM:	119054380(THG1L)

PDIC:

114510084(THG1L)

PHAS:

123809240(THG1L)

MMF:	118643593(THG1L)

PPAM:

129066361(THG1L)

HAI:	109388889(THG1L)

RFQ:	117017110(THG1L)

PALE:

102882192(THG1L)

PGIG:

120614009(THG1L)

PVP:	105289911(THG1L)

RAY:	107521934(THG1L)

MJV:	108409382(THG1L)

TOD:	119236080(THG1L)

SARA:

101541788(THG1L)

SETR:

126011974(THG1L)

LAV:	100656079(THG1L)

TMU:

101346108

ETF:	101664171(THG1L)

DNM:	101437082(THG1L)

MDO:	100025355(THG1L)

GAS:	123235578(THG1L)

SHR:	100928502(THG1L)

AFZ:

127550139

PCW:	110212399(THG1L)

OAA:	100075219(THG1L)

GGA:	416242(THG1L)

PCOC:

116232105(THG1L)

MGP:	100541621(THG1L)

CJO:	107320397(THG1L)

TPAI:

128081439(THG1L)

LMUT:

125700353(THG1L)

NMEL:

110405384(THG1L)

APLA:

101790653(THG1L)

ACYG:

106032687(THG1L)

CATA:

118254543(THG1L)

AFUL:

116494685(THG1L)

TGU:	100223262(THG1L)

LSR:	110470841(THG1L)

SCAN:

103817499(THG1L)

PMOA:

120498702(THG1L)

OTC:	121332513(THG1L)

PRUF:

121361444(THG1L)

GFR:	102037256(THG1L)

FAB:	101806182(THG1L)

OMA:	130258759(THG1L)

PHI:	102104035(THG1L)

PMAJ:

107210915(THG1L)

CCAE:

111935491(THG1L)

CCW:	104689676(THG1L)

CBRC:

103611539(THG1L)

ETL:	114058336(THG1L)

ZAB:	102067709(THG1L)

SVG:	106852949(THG1L)

MMEA:

130581358(THG1L)

HRT:	120759196(THG1L)

FPG:	101915135(THG1L)

FCH:	102051978(THG1L)

CLV:	102088249(THG1L)

EGZ:	104122569(THG1L)

NNI:	104014230(THG1L)

PLET:

104615070(THG1L)

EHS:	104510197(THG1L)

PCAO:

104051344(THG1L)

ACUN:

113485440(THG1L)

TALA:

104358983(THG1L)

PADL:

103924928(THG1L)

AFOR:

103904542(THG1L)

ACHC:

115334325(THG1L)

HALD:

104311974(THG1L)

HLE:	104838941(THG1L)

AGEN:

126051061

GCL:

127021927

CCRI:

104156324(THG1L)

CSTI:

104563865(THG1L)

MUI:	104541999(THG1L)

BREG:

104629142(THG1L)

FGA:	104078550(THG1L)

GSTE:

104252077(THG1L)

LDI:	104340059(THG1L)

MNB:	103777426(THG1L)

OHA:	104336741(THG1L)

NNT:	104400355(THG1L)

SHAB:

115615591(THG1L)

DPUB:

104303977(THG1L)

PGUU:

104457621(THG1L)

ACAR:

104519031(THG1L)

CPEA:

104392689(THG1L)

CVF:	104293900(THG1L)

RTD:	128916333(THG1L)

CUCA:

104063096(THG1L)

TEO:	104370392(THG1L)

BRHI:

104495682(THG1L)

AAM:	106493653(THG1L)

AROW:

112964851(THG1L)

NPD:	112954525(THG1L)

DNE:	112994372(THG1L)

SCAM:

104151112(THG1L)

ASN:	102385703(THG1L)

AMJ:	102571463(THG1L)

CPOO:

109310213(THG1L)

GGN:	109289843(THG1L)

PSS:	102459768(THG1L)

CMY:	102941033(THG1L)

CCAY:

125641979(THG1L)

DCC:	119860622(THG1L)

CPIC:

101950893(THG1L)

TST:	117881948(THG1L)

CABI:

116836687(THG1L)

MRV:	120370309(THG1L)

ACS:	100567729(thg1l)

ASAO:

132769006(THG1L)

PVT:	110077850(THG1L)

SUND:

121924084(THG1L)

PBI:	103056892(THG1L)

PMUR:

107302956(THG1L)

CTIG:

120318149(THG1L)

TSR:	106552162(THG1L)

PGUT:

117654714(THG1L)

APRI:

131192081(THG1L)

PTEX:

113433848(THG1L)

NSS:	113421647(THG1L)

VKO:	123034009(THG1L)

PMUA:

114591402(THG1L)

PRAF:

128408016(THG1L)

ZVI:	118080467(THG1L)

HCG:	128343308(THG1L)

GJA:	107115677(THG1L)

STOW:

125428297(THG1L)

EMC:	129327327(THG1L)

XLA:	495483(thg1l.L)

XTR:	100487878(thg1l)

NPR:	108786333(THG1L)

RTEM:

120932585(THG1L) 120946740

BBUF:

121007762(THG1L)

BGAR:

122928432(THG1L)

MUO:	115476214(THG1L)

GSH:	117351759(THG1L)

DRE:	492814(thg1l)

SRX:	107746540 107751338

SANH:

107680932(thg1l)

SGH:	107551452(thg1l) 107580781 107587123

CCAR:

109066864 109102429

CAUA:

113057666 113078452 113098246

CGIB:

127971848 128027027

PTET:

122357321 122357791(thg1l)

LROH:

127175839(thg1l)

OMC:	131553745(thg1l)

PPRM:

120460584(thg1l)

RKG:	130072517(thg1l)

MAMB:

125259440(thg1l)

CIDE:

127494783

MASI:

127412728 127417614

TROS:

130563897(thg1l)

TDW:	130437942(thg1l)

MANU:

129422823(thg1l)

IPU:

108274462

IFU:	128618635(thg1l)

PHYP:

113529952(thg1l)

SMEO:

124391902(thg1l)

TFD:	113659877(thg1l)

TVC:	132856831(thg1l)

AMEX:

103044514(thg1l)

CMAO:

118811518(thg1l)

EEE:	113581315(thg1l)

CHAR:

105898435(thg1l)

TRU:	101073616(thg1l)

TFS:	130530984(thg1l)

TNG:	GSTEN00031660G001

LCO:	104924232(thg1l)

NCC:	104946880(thg1l)

TBEN:

117475235(thg1l)

CGOB:

115014905(thg1l)

PGEO:

117453828(thg1l)

GACU:

117545221(thg1l)

EMAC:

134860008(thg1l)

ELY:	117260561(thg1l)

EFO:	125894946(thg1l)

PLEP:

121948173(thg1l)

SLUC:

116042148(thg1l)

ECRA:

117952053(thg1l)

ESP:	116686748 116697112

PFLV:

114562907(thg1l)

GAT:	120817542(thg1l)

PPUG:

119210445(thg1l)

AFB:	129090322(thg1l)

CLUM:

117737828(thg1l)

PSWI:

130209648(thg1l)

MSAM:

119882146 119888307

SCHU:

122880851(thg1l)

CUD:	121516834(thg1l)

ALAT:

119007360(thg1l)

MZE:	101485778(thg1l)

ONL:	100707811(thg1l)

OAU:	116324599(thg1l)

OLA:	101162300(thg1l)

OML:	112153318(thg1l)

CSAI:

133446821(thg1l)

XMA:	102225768(thg1l)

XCO:	114139136(thg1l)

XHE:	116713935(thg1l)

PRET:

103470877(thg1l)

PFOR:

103154062 103154066

PLAI:

106955424(thg1l)

PMEI:

106912891 106912903

GAF:	122837550(thg1l)

PPRL:

129362620(thg1l)

CVG:	107086193(thg1l)

CTUL:

119776635(thg1l)

GMU:	124860017(thg1l)

NFU:	107396285(thg1l)

KMR:	108245800(thg1l)

ALIM:

106521918(thg1l)

NWH:	119409097(thg1l)

AOCE:

111588055(thg1l)

MCEP:

125008016(thg1l)

CSEM:

103391403(thg1l)

POV:	109625356(thg1l)

SSEN:

122778980(thg1l)

HHIP:

117769370(thg1l)

HSP:	118111970(thg1l)

SMAU:

118319738(thg1l)

LCF:

108882804

SDU:	111226618(thg1l)

SLAL:

111664660(thg1l)

XGL:	120785416(thg1l)

HCQ:	109524369(thg1l)

SSCV:

125991013

SBIA:

133508545(thg1l)

PEE:	133407616(thg1l)

PTAO:

133484875(thg1l)

BPEC:

110162409(thg1l)

MALB:

109955573(thg1l)

BSPL:

114864755(thg1l)

SJO:	128363355(thg1l)

SASA:

100195605(thg1) 106604278

STRU:

115189507

OTW:	112238099(thg1l)

OMY:	100305306(yg1g)

OGO:	124011077(thg1l)

ONE:

115120568

OKI:	109904968(thg1l)

OKE:	118372983(thg1l) 118381557

SALP:

111967214(thg1l)

SNH:	120035096 120041200

CCLU:

121536730(thg1l) 121539421

ELS:	105024422(thg1l)

SFM:	108936756(thg1l)

PKI:	111860716(thg1l)

AANG:

118222186(thg1l)

LOC:	102690540(thg1l)

PSPA:

121297291 121323830(thg1l)

ARUT:

117413410 117431376

PSEX:

120542085(thg1l)

LCM:	102352205(THG1L)

CMK:	103177299(thg1l)

RTP:	109918348(thg1l)

CPLA:

122556795(thg1l)

HOC:	132823335(thg1l)

LERI:

129701431(thg1l)

PMRN:

116947633(THG1L)

LRJ:	133351647(THG1L)

BFO:

118413890

BBEL:

109463188

CIN:

100179812

SCLV:

120335693

SPU:

587315

LPIC:

129273312

APLC:

110977035

AJC:

117105684

SKO:

100374565

DME:	Dmel_CG4103(THG)

DER:

6541952

DSE:

6611322

DSI:	Dsimw501_GD21976(Dsim_GD21976)

DYA:	Dyak_GE24732

DAN:

6497812

DSR:

110185778

DPO:

4817877

DPE:

6593697

DMN:

108162490

DWI:

6643485

DGR:

6561978

DMO:	Dmoj_GI17333

DAZ:

108611150

DNV:

115563993

DHE:

111598939

DVI:

6628657

CCAT:

101462141 111591800

BOD:

106623641

BDR:

105222564

RZE:	108365405 108380537

AOQ:

129237911

TDA:	119671222 119671231 119672674

MDE:	101889710 131802097

SCAC:

106089880

LCQ:

111675623

LSQ:

119600565

GFS:

119634302

ECOE:

129948355

CLON:

129619073

HIS:

119657679

AGA:

1280888

ACOZ:

120958749

AARA:

120903816

AMER:

121599138

ASTE:

118505980

AFUN:

125767068

AMOU:

128310854

AALI:

118462664

AAG:

5579197

AALB:

109431470

CQU:	CpipJ_CPIJ000684

CPII:

120429691

CNS:

116343915

BCOO:

119067267

AME:

410055

ACER:

108001867

ALAB:

122718963

ADR:

102672414

AFLR:

100866487

BIM:

100741551

BBIF:

117214792

BVK:

117233392

BVAN:

117166735

BTER:

100651919

BAFF:

126915765

BPYO:

122568809

BPAS:

132910140

FVI:

122530456

CCAL:

108623165

OBB:

114878398

OLG:

117611966

MGEN:

117222216

NMEA:

116429641

CGIG:

122403545

SOC:

105206596

MPHA:

105840947

AEC:

105147260

ACEP:

105625037

PBAR:

105426638

VEM:

105558558

HST:

105182218

DQU:

106749437

CFO:

105248169

FEX:

115246153

LHU:

105673503

PGC:

109856660

OBO:

105277772

PCF:

106790620

PFUC:

122525587

VPS:

122633496

VCRB:

124429322

VVE:

124953772

NVI:

100117826

CSOL:

105363895

TPRE:

106654601

LHT:

122499668

LBD:

127286173

MDL:

103569867

CGLO:

123259199

FAS:

105271581

DAM:

107048145

AGIF:

122847459

CINS:

118069273

VCAN:

122412024

CCIN:

107273640

DSM:

124405214

NPT:

124211899

NFB:

124175227

NLO:

107222222

NVG:

124297501

AROA:

105691417

TCA:

663767

DPA:

109539731

SOY:

115888846

AGRG:

126741194

ATD:

109596315

CSET:

123311278

AGB:

108908249

LDC:

111505043

NVL:

108558615

APLN:

108738094

PPYR:

116171280 116171374

OTU:

111424759

BMOR:

692885

BMAN:

114248345

MSEX:

115449397

DPL:	KGM_211096

BANY:

112051098

MJU:

123868746

NIQ:

126780921

VCD:

124531013

MCIX:

123669502

PMAC:

106719786

PPOT:

106099694

PXU:

106118225

PRAP:

110999638

PBX:

123712604

PNAP:

125056912

ZCE:

119831185

CCRC:

123705847

LSIN:

126968979

AAGE:

121725357

HAW:	110371951(thg)

HZE:

124646371

TNL:

113493474

SLIU:

111363137

OFU:

114354550

PXY:

105387318

PGW:

126369664

CFEL:

113366709 113390979

CCRN:

123299895

API:

100165160

DNX:

107174143

AGS:

114124374

RMD:

113555535

ACOO:

126838103

DVT:

126907149

BTAB:

109036128 109036130

DCI:

103505947

CLEC:

106672812

HHAL:

106685473

NLU:

111054802

HVI:	124357725 124373836

MQU:

128986231

PHU:	Phum_PHUM410370

FOC:

113206036

TPAL:

117651895

ZNE:

110836441

CSEC:

111869882

BROR:

134540732

IEL:

124168858

DPX:	DAPPUDRAFT_39947

DMK:

116919710

DPZ:

124343304

PVM:

113800668

PJA:

122246005

PMOO:

119596417

HAME:

121870528

PCLA:

123772137

CQD:

128688381

PTRU:

123498723

ESN:

127002176

MNZ:

135222951

EAF:

111697693

LSM:

121124333

DSV:

119442807

RSAN:

119387973

RMP:

119188183

VDE:

111246703

VJA:

111264075

TUT:

107368606

DPTE:

113790390

DFR:

124492640

CSCU:

111642360

PTEP:

107441137

ABRU:

129966953

UDV:

129222953

SDM:

118184226

LPOL:

106472815

PMEO:

129593503

HRO:	HELRODRAFT_155808

LGI:	LOTGIDRAFT_115350

PVUL:

126816211

PCAN:

112563855

BGT:

106061300

GAE:

121384369

HRF:

124138498

HRJ:

124267552

CRG:

105317995

CVN:

111102241

CANU:

128181776

OED:	125659329 125678058

MYI:

110452037

PMAX:

117319880 117339410

MCAF:

127735880

MMER:

123547202

RPHI:

132759858

DPOL:

127841809 127842884

OBI:

106880761

OSN:

115222557

LAK:

106164463

OVI:	T265_14691

EGL:

EGR_02605

NVE:

5520254

EPA:

110238492

ATEN:

116296288

ADF:

107345634

AMIL:

114958174 114958205

PDAM:

113673664

SPIS:

111340151

DGT:

114519637

XEN:

124448149

HMG:

100205492

HSY:

130655010

TAD:	TRIADDRAFT_32525 TRIADDRAFT_55308

AQU:

100636648

ATH:	AT2G31580 AT2G32320

ALY:	9298925 9317249

CRB:	17889197 17889432 17889503

CSAT:

104700225 104700306 104749634 104749738 104786351 104786354 104786461

EUS:	EUTSA_v10016524mg

BRP:	103857389 103867714

BNA:	106391044 106392395 106437722 106445690

BOE:	106329833 106337476

RSZ:	108807291 108813816 108827686 108828391 108845426 130504187 130509169

THJ:

104800903

CPAP:

110820238

CIT:

102626328

PVY:	116108287 116111092

MINC:

123199777

TCC:

18597151

GRA:

105768445

GHI:	107905929 107958272

GAB:

108450365

HSYR:

120190794

DZI:

111275196

EGR:

104415843

GMX:	100802539 100810659 100817433

GSJ:	114372276 114389412 114405598

PVU:	PHAVU_010G125700g

VRA:

106770861

VAR:	108324927 108339100

VUN:

114190455

CCAJ:

109789604

APRC:

113865216

MTR:

25499683

TPRA:

123889667

CAM:

101503826

PSAT:

127132228

VVO:	131603230 131610670 131632109

LJA:	Lj5g3v0523190.1(Lj5g3v0523190.1) Lj5g3v0523190.2(Lj5g3v0523190.2) Lj6g3v0291920.1(Lj6g3v0291920.1)

ADU:

107457887

AIP:

107608738

AHF:	112702536 112764412

LANG:

109326607 109329221

PCIN:

129290336 129296318

QSA:	O6P43_028649 O6P43_031237

FVE:	101307565 101314791

RCN:	112173350 112183934

PPER:

18793967

PMUM:

103318902

PAVI:

110754953 110765697

PDUL:

117627784

MDM:

103444673

MSYL:

126584884 126620985

PXB:	103931668 103965255

MNT:

21405070

CSAV:

115699264 115714696

CSV:

101208636

CMO:

103484683

BHJ:

120074586

MCHA:

111005370

CMAX:

111478015

CMOS:

111453416

CPEP:

111804307

RCU:

8264047

JCU:

105636568

HBR:	110664462 110664493 110666869

MESC:

110626806

POP:

7466188

PEU:

105138407

PALZ:

118043900

JRE:

109005357

CILL:

122295349 122304564

CAVE:

132165241 132173585

QSU:

111985114

QLO:

115995330

TWL:

120002675

VVI:

100264494

VRI:

117918916

SLY:

101259833

SPEN:

107017998

SOT:	102591786 102600251

SSTN:

125855207 125856629 125860497

SDUL:

129901755

CANN:

107840624

LBB:

132613545

NTA:	107788909 107800326 107816514

NSY:	104212755 104239181

NTO:

104086625

NAU:	109210500 109239015

INI:	109160835 109190590

ITR:	116016130 116027252 116027354

SIND:

105178315

OEU:	111394711 111397080

EGT:

105977248

SSPL:

121748281 121767258 121770937 121789395 121790126 121791829

SMIL:

130993935

SHIS:

125200830 125201700 125202562 125210589

APAN:

127263081

HAN:

110886359

ECAD:

122595645

LSV:

111881383

CCAV:

112526374

DCR:

108197562

CSIN:

114310625

RVL:	131303266 131331444

AEW:

130762524

BVG:	104894410 104909094

SOE:

110803554

CQI:	110682550 110706826 110718765

ATRI:

130823544

MOF:

131160183

NNU:

104605504

MING:

122094065

TSS:	122662391 122666606

PSOM:

113286460 113292611 113298353 113302343

OSA:

4339440

DOSA:

Os05t0535500-01(Os05g0535500)

OBR:

102722215

OGL:

127773709

BDI:	100833571 100841135

ATS:	109736984 109738565

TDC:	119267754 119275627 119293367 119299358 119307540

TAES:

123058199 123069455 123077969 123102336 123110529 123119525 123158120

TUA:	125507917 125543489

LPER:

127321797 127342139

LRD:

124674844

SBI:

8068980

ZMA:

103630654

SITA:

101774960

SVS:

117849962

PVIR:

120664812 120673520 120698011

PHAI:

112884021

PDA:

103706302

EGU:

105045590

MUS:

103993905

ZOF:	122022818 122053928

DCT:

110116034

PEQ:	110032678 110033545

AOF:

109820342

MSIN:

131223439 131243943

NCOL:

116267442

ATR:

18428407

SMO:	SELMODRAFT_105392 SELMODRAFT_232047

PPP:

112284865

CRE:	CHLRE_13g581550v5

VCN:	VOLCADRAFT_58584

MNG:

MNEG_7545

CSL:	COCSUDRAFT_37376

CVR:	CHLNCDRAFT_19326

APRO:

F751_0510

CME:	CYME_CMR286C

GSL:	Gasu_05930

CCP:	CHC_T00007905001

SCE:	YGR024C(THG1)

SEUB:

DI49_1987

SPAO:

SPAR_G02530

AGO:	AGOS_ABR031C

ERC:

Ecym_2419

KLA:	KLLA0_B06237g

KMX:	KLMA_50212(THG1)

LTH:	KLTH0G17270g

VPO:	Kpol_526p19

ZRO:	ZYRO0A12144g

CGR:	CAGL0J00209g

NDI:	NDAI_0D03900(NDAI0D03900)

TPF:	TPHA_0F00940(TPHA0F00940)

TBL:	TBLA_0G01180(TBLA0G01180)

TGB:	HG536_0C04030

TDL:	TDEL_0D02910(TDEL0D02910)

KAF:	KAFR_0F03760(KAFR0F03760)

KNG:	KNAG_0D03850(KNAG0D03850)

ZMK:	HG535_0A08420

PPA:	PAS_chr1-4_0323

DHA:	DEHA2F22880g

PIC:	PICST_60761

PGU:	PGUG_00408

SPAA:

SPAPADRAFT_144742

LEL:	PVL30_005030(THG1)

CAL:	CAALFM_C700560CA(THG1)

CTP:	CTRG_05039

COT:	CORT_0H01070

CDU:	CD36_70100

CTEN:

CANTEDRAFT_103850

YLI:	YALI0E09823g

CLU:	CLUG_03111

CLUS:

A9F13_12g01309

CAUR:

CJI96_0001596

SLB:	AWJ20_712(THG1)

PKZ:	C5L36_0B07450

BNN:	FOA43_000523(THG1)

BBRX:

BRETT_003139(THG1)

OPA:	HPODL_02988

SLUD:

SCDLUD_000628

NCR:

NCU02105

NTE:	NEUTE1DRAFT70540(NEUTE1DRAFT_70540)

SMP:	SMAC_05003

PAN:	PODANSg09507

PBEL:

QC761_102630(THG1)

PPSD:

QC762_102630(THG1)

PPSP:

QC763_102630(THG1)

PPSA:

QC764_102630(THG1)

TTT:	THITE_2156116

MTM:	MYCTH_2294522

MGR:

MGG_14742

PPEI:

PpBr36_00317

PGRI:

PgNI_04783

SSCK:

SPSK_05320

FGR:	FGSG_00914

FPU:	FPSE_12058

FPOA:

FPOAC1_000972(RGT1)

FVN:	FVRRES_01143

FVR:	FVEG_00681

FOX:	FOXG_00885

NHE:	NECHADRAFT_30739 NECHADRAFT_87153

FFC:	NCS54_00137100

FKR:	NCS57_00134300

FMU:	J7337_001305(RGT1)

TRE:	TRIREDRAFT_64065

TRR:	M419DRAFT_9549

MAW:

MAC_07406

MAJ:

MAA_00661

PCHM:

VFPPC_16072

CMT:

CCM_05483

AMUS:

LMH87_006043

PLJ:	VFPFJ_09060

PTKZ:

JDV02_009376(THG1)

VAL:	VDBG_07404

VDA:	VDAG_06112

CFJ:	CFIO01_11605

CLUP:

CLUP02_13736

CHIG:

CH63R_05835

SAPO:

SAPIO_CDS5513

PFY:	PFICI_06960

SSL:	SS1G_06165

BFU:	BCIN_05g04330(Bcthg1)

MBE:

MBM_03855

PSCO:

LY89DRAFT_713406

GLZ:	GLAREA_10834

ANI:	ANIA_00804

AFM:	AFUA_1G14630

ACT:	ACLA_020800

NFI:	NFIA_010790

AOR:	AO090003000484

ANG:	An01g12630

AFV:	AFLA_001203

ALUC:

AKAW2_10352A(THG1)

ACHE:

ACHE_30629A(THG1)

APUU:

APUU_51024A(THG1)

PCS:	N7525_010420

PDP:	PDIP_66330

POU:	POX_c03798

TMF:	EYB26_006079

CIM:	CIMG_13693(CIMG03241)

CPW:	CPC735_009350

PBL:	PAAG_05399

PBN:	PADG_06749

BGH:	BDBG_06470

PNO:	SNOG_06471 SNOG_14258

PTE:

PTT_06635

BZE:	COCCADRAFT_101248

BSC:	COCSADRAFT_32927

BOR:	COCMIDRAFT_105995

AALT:

CC77DRAFT_1020374

ARAB:

EKO05_0003891

ZTR:	MYCGRDRAFT_70961

PFJ:	MYCFIDRAFT_80470

FFU:	CLAFUR5_04360

CBET:

CB0940_11802

BCOM:

BAUCODRAFT_66046

NPA:	UCRNP2_4848

TML:	GSTUM_00002202001 GSTUM_00004516001

SPO:

SPCC63.07

SOM:	SOMG_04398(thg1)

CNE:

CNC02800

CNB:

CNBC4410

CNG:	CNAG_01788

CGI:	CGB_C4250C

CDEU:

CNBG_3316

TASA:

A1Q1_01016

CCAC:

CcaHIS019_0203610(THG1)

PPL:	POSPLDRAFT_87675 POSPLDRAFT_88866

TVS:	TRAVEDRAFT_125822

DSQ:	DICSQDRAFT_52423

PCO:	PHACADRAFT_202682

SHS:	STEHIDRAFT_149550

HIR:	HETIRDRAFT_384464

PSQ:	PUNSTDRAFT_77145

ADL:	AURDEDRAFT_107511 AURDEDRAFT_146700

FME:	FOMMEDRAFT_102750

GTR:	GLOTRDRAFT_44306

RSX:	RhiXN_11134

LBC:	LACBIDRAFT_252840

CCI:	CC1G_06232

ABP:	AGABI1DRAFT121643(AGABI1DRAFT_121643)

ABV:	AGABI2DRAFT200849(AGABI2DRAFT_200849)

PCUB:

JR316_0006409

MRR:	Moror_16124

E1B28_011739

SCM:	SCHCO_02501794(SCHCODRAFT_02501794)

CPUT:

CONPUDRAFT_51284

SLA:	SERLADRAFT_469096

WSE:	WALSEDRAFT_14367

WIC:	J056_004141

UMA:	UMAG_11605

PFP:	PFL1_06270

SGRA:

EX895_000611

MGL:

MGL_1763

MRT:

MRET_4364

MSYM:

MSY001_3400

PGR:	PGTG_09911

PTRC:

PtA15_11A394

PSTR:

Pst134EA_017553

MLR:	MELLADRAFT_39614

MBR:	MONBRDRAFT_31372

SRE:	PTSG_08280

DDI:	DDB_G0291830(thg1)

DPP:	DICPUDRAFT_152806 DICPUDRAFT_83062

DFA:	DFA_04027(thg1)

PFA:	PF3D7_0723000

PFD:	PFDG_01224

PFH:	PFHG_01261

PREI:

PRSY57_0720200

PGAB:

PGSY75_0723000

PYO:	PY17X_0623200

PCB:	PCHAS_0622200

PBE:	PBANKA_0620500

PVV:	PVVCY_0602080

PKN:	PKNH_0318400

PVX:	PVX_096205

PCY:	PCYB_032680

PMAL:

PMUG01_03029400

PREL:

PRELSG_0200400

TAN:

TA19625

TPV:

TP01_0248

TOT:	TOT_010000235

BEQ:	BEWA_032070

BBO:	BBOV_IV004960

BMIC:

BMR1_02g00695

BBIG:

BBBOND_0210020

CPV:

cgd1_1990

CHO:	Chro.10228

TET:	TTHERM_00085230 TTHERM_00373760

PTM:	GSPATT00002474001

SPAR:

SPRG_05518 SPRG_16419

EHX:	EMIHUDRAFT_467671

TVA:	TVAG_2v0553400

AGU:

AS4_41750

ABER:

BSR55_00855

MBOI:

DQF64_09160

MII:	BTJ40_20210

THIS:

HZT40_21135

TSY:	THSYN_30520

HAHE:

ENC22_29290

HAHH:

O5O45_27235

GSN:	YC6258_03570

OME:	OLMES_4077

CHJ:	NCTC10426_00034

NEL:	NELON_01025

NFV:	FAH67_02820

NPF:	LPB400_05865

NMB:	MON40_05855

JEU:	BJP62_13800

MASS:

CR152_03095

BOS:	BSY19_5401

LABR:

CHH27_16800

MXA:

MXAN_5968

MSD:	MYSTI_06577

MYM:	A176_000934

MFB:	MFUL124B02_34640

MYX:	QEG98_32785

CCX:	COCOR_06225

AGE:	AA314_08627

AVM:	JQX13_25535

CFUS:

CYFUS_009385

SCL:

sce6062

MRM:	A7982_07483

SAMY:

DB32_001442

LLU:	AKJ09_10793

PCAY:

FRD00_09285

BTG:	BTB_502p01420

BTN:	BTF1_31137

PPY:

PPE_03273

PPM:	PPSC2_17335

PPO:	PPM_3497(M1_3866)

PPQ:	PPSQR21_034940

PPOY:

RE92_19765

POD:	PODO_22980

PPEO:

ABE82_17415

PKB:	B4V02_07995

PLUT:

EI981_17945

PBK:	Back11_02720

PMAE:

LMZ02_31065

SACA:

FFV09_04480

JEO:

JMA_37590

CCL:	Clocl_2735

CMAT:

HBA49_05510

NFA:

NFA_39460

NFR:	ERS450000_05973

SSUB:

CP968_25975

ACH:

Achl_4028

ACTW:

F7P10_15920

AMAZ:

LUW76_28725

AOI:

AORI_7608

AJA:	AJAP_39670

AMYB:

BKN51_31330

AORI:

SD37_02560

AROO:

NQK81_23085

KPHY:

AOZ06_03695

CMP:	Cha6605_5557

AMR:

AM1_3767

ACAM:

HRE53_15610

LEN:	LEP3755_10150

ONI:	Osc7112_3256

MIC:	Mic7113_1706

NOE:	CLI64_06055

CSG:	Cylst_4454

CALO:

Cal7507_3479

CALT:

Cal6303_0294

CALN:

NIES2098_25310

RIV:	Riv7116_6008

TOQ:	HCG51_06885

ALAX:

NIES50_20020

HAU:

Haur_4049

DEZ:	DKM44_01045

DTAE:

LAJ19_19675

ROO:	G5S37_26735

AAGG:

ETAA8_41150

PND:	Pla175_23780

PLM:

Plim_1513

PEH:	Spb1_23210

PLS:	VT03_21820

FMR:	Fuma_00130

GIM:	F1728_23705

GPN:	Pan110_40660

SDYN:

Mal52_31350

GES:	VT84_06210

GOG:	C1280_26335

GMS:	SOIL9_55920

LRS:	PX52LOC_06101

FTJ:

FTUN_1176

AGV:	OJF2_48870

HBS:	IPV69_14825

STR:	Sterm_2087

ALQ:	C7Y71_000400

CPI:

Cpin_5797

CHIH:

GWR21_09240

CFIL:

MYF79_25070

NKO:	Niako_5206

FLN:

FLA_2484

PEK:	FFJ24_007615

PRK:	H9N25_07890

MGK:	FSB76_16880

MRUB:

DEO27_013650

MGOS:

DIU38_005605

MMAB:

HQ865_13445

MJJ:	PQO05_23845

RHOZ:

GXP67_32375

HSW:

Hsw_2181

HTB:	MTX78_11375

CHK:	D4L85_10160

CARH:

EGY05_04085

CCAU:

EG346_24030

METZ:

METMT2_1003

MST:

Msp_1147

METB:

AW729_10040

MRU:	mru_0676(thgL)

MSI:

Msm_0463

MEB:	Abm4_0407(thgL)

MMIL:

sm9_0550(thgL)

MEYE:

TL18_02585

MOL:

YLM1_0321

MEL:	Metbo_0420

MEW:	MSWAN_1955

METH:

MBMB1_1585

MFC:	BRM9_0820(thgL)

MFI:	DSM1535_0783

MCUB:

MCBB_1883

MSUB:

BK009_06920

METN:

BK008_02560

METT:

CIT01_02610

METO:

CIT02_10025

MFV:

Mfer_0042

MKA:

MK0093

MBU:

Mbur_1464

MMET:

MCMEM_1963

MMH:

Mmah_1763

MHAZ:

BHR79_04865

MEV:	Metev_1115

MPY:

Mpsy_2154

MZI:	HWN40_11460

MHZ:	Metho_2060

MTP:

Mthe_0875

MHI:

Mhar_0345

MHU:

Mhun_0610

MRTJ:

KHC33_10405

MLA:

Mlab_0759

MEM:	Memar_0402

MBG:	BN140_0199

MEMA:

MMAB1_0253

MCHK:

MchiMG62_05300

MSUM:

OH143_08705

MPI:

Mpet_2135

MBN:

Mboo_2270

MFO:	Metfor_0392

MPL:

Mpal_0151

MPD:

MCP_2556

MEZ:

Mtc_0578

RCI:

RCIX455

KCR:

Kcr_1204

BARC:

AOA65_0922

BARB:

AOA66_0326

» show all

Reference

1 [PMID:1660462]

Authors

Jahn D, Pande S

Title

Histidine tRNA guanylyltransferase from Saccharomyces cerevisiae. II. Catalytic mechanism.

Journal

J Biol Chem 266:22832-6 (1991)

Reference

2 [PMID:1660461]

Authors

Pande S, Jahn D, Soll D

Title

Histidine tRNA guanylyltransferase from Saccharomyces cerevisiae. I. Purification and physical properties.

Journal

J Biol Chem 266:22826-31 (1991)

Reference

3 [PMID:14633974]

Authors

Gu W, Jackman JE, Lohan AJ, Gray MW, Phizicky EM

Title

tRNAHis maturation: an essential yeast protein catalyzes addition of a guanine nucleotide to the 5' end of tRNAHis.

Journal

Genes Dev 17:2889-901 (2003)
DOI:10.1101/gad.1148603

Sequence

[sce:YGR024C]

Reference

4 [PMID:20660484]

Authors

Placido A, Sieber F, Gobert A, Gallerani R, Giege P, Marechal-Drouard L

Title

Plant mitochondria use two pathways for the biogenesis of tRNAHis.

Journal

Nucleic Acids Res 38:7711-7 (2010)
DOI:10.1093/nar/gkq646

Sequence

[ath:AT2G31580 AT2G32320]

Reference

5 [PMID:18366186]

Authors

Jackman JE, Phizicky EM

Title

Identification of critical residues for G-1 addition and substrate recognition by tRNA(His) guanylyltransferase.

Journal

Biochemistry 47:4817-25 (2008)
DOI:10.1021/bi702517q

Reference

6 [PMID:21059936]

Authors

Hyde SJ, Eckenroth BE, Smith BA, Eberley WA, Heintz NH, Jackman JE, Doublie S

Title

tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases.

Journal

Proc Natl Acad Sci U S A 107:20305-10 (2010)
DOI:10.1073/pnas.1010436107

Sequence

[hsa:54974]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.7.79

IUBMB Enzyme Nomenclature:

2.7.7.79

ExPASy - ENZYME nomenclature database:

2.7.7.79

BRENDA, the Enzyme Database:

2.7.7.79

DBGET integrated database retrieval system