Entry
Name
thiosulfate---thiol sulfurtransferase;
glutathione-dependent thiosulfate reductase;
sulfane reductase;
sulfane sulfurtransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfurtransferases
BRITE hierarchy
Sysname
thiosulfate:thiol sulfurtransferase
Reaction(IUBMB)
thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide [RN:
R01875 ]
Reaction(KEGG)
Substrate
Product
Comment
The primary product is glutathione hydrodisulfide, which reacts with glutathione to give glutathione disulfide and sulfide. L-Cysteine can also act as acceptor.
History
EC 2.8.1.3 created 1982
Pathway
Reference
Authors
PECK HD Jr, FISHER E Jr.
Title
The oxidation of thiosulfate and phosphorylation in extracts of Thiobacillus thioparus.
Journal
J Biol Chem 237:190-7 (1962)
Reference
2
Authors
Sido, B. and Koj, A.
Title
Separation of rhodanese and thiosulfate reductase activities in carp liver extracts.
Journal
Acta Biol Cracow Ser Zoo 15:97-103 (1972)
Reference
Authors
Uhteg LC, Westley J.
Title
Purification and steady-state kinetic analysis of yeast thiosulfate reductase.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 2.8.1.3
ExPASy - ENZYME nomenclature database: 2.8.1.3
BRENDA, the Enzyme Database: 2.8.1.3