KEGG ENZYME: 2.8.2.16

ENZYME: 2.8.2.16

Entry

EC 2.8.2.16                 Enzyme

Name

thiol sulfotransferase;
phosphoadenylylsulfate-thiol sulfotransferase;
PAPS sulfotransferase;
adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase;
3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase

Class

Transferases;
Transferring sulfur-containing groups;
Sulfotransferases

Sysname

3'-phosphoadenylyl-sulfate:thiol S-sulfonotransferase

Reaction(IUBMB)

3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate [RN:R01236]

Reaction(KEGG)

R01236

Substrate

3'-phosphoadenylyl sulfate [CPD:C00053];
thiol [CPD:C00145]

Product

adenosine 3',5'-bisphosphate [CPD:C00054];
S-alkyl thiosulfate [CPD:C02885]

Comment

Also acts on dithiols; substrates include glutathione, dithioerythritol and 2,3-bis(sulfanyl)propan-1-ol.

History

EC 2.8.2.16 created 1984

Reference

1 [PMID:24424637]

Authors

Schmidt A

Title

The adenosine-5'-phosphosulfate sulfotransferase from spinach (Spinacea oleracea L.). Stabilization, partial purification, and properties.

Journal

Planta 130:257-63 (1976)
DOI:10.1007/BF00387830

Reference

Authors

Schmidt, A. and Christen, U.

Title

A PAPS-dependent sulfotransferase in Cyanophora paradoxa inhibited by 5'-AMP, 5'-ADP and APS.

Journal

Z Naturforsch C: Biosci 34:222-228 (1979)

Reference

Authors

Tsang, M.

Title

L.-S. and Schiff, J.A. Studies of sulfate utilization by algae. 17. Reactions of the adenosine 5'-phosphosulfate (APS) sulfotransferase from Chlorella and studies of model reactions which explain the diversity of side products with thiols.

Journal

Plant Cell Physiol 17:1209-1220 (1976)

Other DBs

ExplorEnz - The Enzyme Database:

2.8.2.16

IUBMB Enzyme Nomenclature:

2.8.2.16

ExPASy - ENZYME nomenclature database:

2.8.2.16

BRENDA, the Enzyme Database:

2.8.2.16

CAS:	70356-45-5

All links

Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
All databases (7)   

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