Entry |
|
Name |
ADP-dependent medium-chain-acyl-CoA hydrolase;
medium-chain acyl coenzyme A hydrolase;
medium-chain acyl-CoA hydrolase;
medium-chain acyl-thioester hydrolase;
medium-chain hydrolase;
myristoyl-CoA thioesterase
|
Class |
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
|
Sysname |
ADP-dependent-medium-chain-acyl-CoA hydrolase
|
Reaction(IUBMB) |
acyl-CoA + H2O = CoA + a carboxylate [RN: R00383]
|
Reaction(KEGG) |
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Substrate |
|
Product |
|
Comment |
Requires ADP; inhibited by NADH. Maximum activity is shown with nonanoyl-CoA.
|
History |
EC 3.1.2.19 created 1992
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Reference |
|
Authors |
Alexson SE, Nedergaard J. |
Title |
A novel type of short- and medium-chain acyl-CoA hydrolases in brown adipose tissue mitochondria. |
Journal |
J Biol Chem 263:13564-71 (1988) |
Other DBs |
ExplorEnz - The Enzyme Database: | 3.1.2.19 |
ExPASy - ENZYME nomenclature database: | 3.1.2.19 |
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