KEGG   ENZYME: 3.1.3.47
Entry
EC 3.1.3.47                 Enzyme                                 
Name
[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase;
reductase phosphatase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphate phosphohydrolase
Reaction(IUBMB)
[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O = [hydroxymethylglutaryl-CoA reductase (NADPH)] + phosphate [RN:R04542]
Reaction(KEGG)
R04542
Substrate
[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate [CPD:C04768];
H2O [CPD:C00001]
Product
[hydroxymethylglutaryl-CoA reductase (NADPH)] [CPD:C04632];
phosphate [CPD:C00009]
Comment
Acts on the product of the reaction catalysed by EC 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase, simultaneously dephosphorylating and activating EC 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH).
History
EC 3.1.3.47 created 1984
Reference
1  [PMID:6282220]
  Authors
Gil G, Hegardt FG.
  Title
Some properties of purified 3-hydroxy-3-methylglutaryl coenzyme A reductase phosphatases from rat liver.
  Journal
Arch Biochem Biophys 214:192-8 (1982)
DOI:10.1016/0003-9861(82)90022-4
Reference
2  [PMID:6260210]
  Authors
Gil G, Sitges M, Hegardt FG.
  Title
Purification and properties of rat liver hydroxymethylglutaryl coenzyme A reductase phosphatases.
  Journal
Biochim Biophys Acta 663:211-21 (1981)
DOI:10.1016/0005-2760(81)90207-1
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.47
IUBMB Enzyme Nomenclature: 3.1.3.47
ExPASy - ENZYME nomenclature database: 3.1.3.47
BRENDA, the Enzyme Database: 3.1.3.47
CAS: 73507-97-8

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
All databases (6)   

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